Cited by Icariin inhibits cisplatin-induced ovarian toxicity via modulating NF-κB and PTEN/AKT/mTOR/AMPK axis

Current Research in Drug-Free Cancer Therapies DOI

Akshaya Andavar,

Varsha Rajesh Bhagavathi,

J Cousin

et al.

Bioengineering, Journal Year: 2025, Volume and Issue: 12(4), P. 341 - 341

Published: March 26, 2025

Cancer treatment has historically depended on conventional methods like chemotherapy, radiation, and surgery; however, these strategies frequently present considerable limitations, including toxicity, resistance, negative impacts healthy tissues. In addressing challenges, drug-free cancer therapies have developed as viable alternatives, utilizing advanced physical biological to specifically target tumor cells while reducing damage normal This review examines several strategies, such high-intensity focused energy beams, nanosecond pulsed electric fields, photothermal therapy well the use of inorganic nanoparticles promote selective apoptosis. We also investigate significance targeting microenvironment, precision medicine, immunotherapy in progression personalized therapies. Although approaches demonstrate significant promise, challenges scalability, safety, regulatory obstacles must be resolved for clinical application. paper presents an overview current research therapies, emphasizing recent advancements, underlying scientific principles, steps required implementation.

Language: Английский

Citations

Preparation and Characterization of Chitosan-Coated Nanostructured Lipid Carriers (CS-NLC) Containing (6)-Gingerol and Investigating their Toxicity Against MCF-7 Breast Cancer Cell Line DOI

Raed Karim Malek Al-Ziyadi,

Nasim Hayati,

Mohammad Reza Rezaei

et al.

BioNanoScience, Journal Year: 2023, Volume and Issue: 14(1), P. 153 - 163

Published: Dec. 14, 2023

Language: Английский

Citations

Facile fabrication and characterization of silver nanoparticles by sunn pest (Eurygaster integriceps puton) damaged wheat and evaluation of its antibacterial and cellular toxicity toward liver cancer cell lines DOI

Mohammad Nateq Golestan, Mohammad Reza Abbasi,

Hasan Rakhshandeh

et al.

Studies in Medical Sciences, Journal Year: 2023, Volume and Issue: 34(10), P. 586 - 597

Published: Dec. 1, 2023

Facile fabrication and characterization of silver nanoparticles by sunn pest (Eurygaster integriceps puton) damaged wheat evaluation its antibacterial cellular toxicity toward liver cancer cell lines

Language: Английский

Citations

Silver‐coated copper nanocomposites synthesis using the essence of Foeniculum vulgare mill and estimation of its antibacterial and cytotoxicity effects DOI

Mohammad Sharifalhoseini,

Gholamhassan Vaezi, Ali Es‐haghi

et al.

Micro & Nano Letters, Journal Year: 2024, Volume and Issue: 19(3)

Published: April 4, 2024

Abstract The Cu 3.96 Ag 0.04 nanoparticles were synthesized using the essence of Foeniculum vulgare Mill for first time. particles fully analysed by conventional characterization methods such as powder X‐ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS). results have shown crystal structure silver copper and crystallite size obtained Scherer equation was 23.2 nm. TEM images interestingly displayed formation nanorods in solid phase with nearly 5 nm widths different lengths up to 100 hydrodynamic is also compatible sizes. Biologically, tested against infective gram negative positive bacteria. synthetic NPs show strong antibacterial properties Also, had an inhibitory effect on growth cancer cells, which dose‐ time‐dependent.

Language: Английский

Citations

Icariin inhibits cisplatin-induced ovarian toxicity via modulating NF-κB and PTEN/AKT/mTOR/AMPK axis DOI

Basma G. Eid, Lenah S. Binmahfouz, Rasheed A. Shaik

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 30, 2024

Language: Английский

Citations