Journal of Fungi,
Journal Year:
2023,
Volume and Issue:
9(12), P. 1161 - 1161
Published: Dec. 3, 2023
Propolis
is
a
resinous
mixture
produced
by
honeybees,
mainly
from
plant
exudates.
With
rich
chemical
composition
including
many
phenolic
compounds,
mostly
responsible
for
its
biological
properties,
namely
antimicrobial
ones,
propolis
may
be
promising
alternative
to
synthetic
pesticides.
The
study
of
the
south
Portugal
and
potential
against
phytopathogenic
agents
are
still
very
recent
different
methodological
approaches
hinder
comparison
efficacies.
In
this
context,
we
aimed
test
value
mathematical
model
multiparametric
characterization
propolis’
antifungal
action
on
solid
medium
assays.
An
ethanol
extract
(EE)
sample
harvested
in
2016
Alves
(A16)
was
characterized
terms
five
species.
A16.EE
(500–2000
µg/mL)
inhibited
mycelial
growth
all
species,
with
Phytophthora
cinnamomi
Biscogniauxia
mediterranea
being
most
susceptible
Colletotrichum
acutatum
least
affected.
Gompertz
proved
suitable
tool
quantitatively
describing
profiles
fungi
oomycetes,
parameters
exhibit
high
level
discrimination.
Our
results
reveal
that
extracts
have
applications
beyond
traditional
uses,
particularly
within
agri-food
sector,
allowing
beekeepers
make
their
businesses
more
profitable
diversified.
Journal of Fungi,
Journal Year:
2025,
Volume and Issue:
11(2), P. 93 - 93
Published: Jan. 24, 2025
Metabolomics
has
emerged
as
a
transformative
tool
in
the
study
of
microbes,
including
pathogenic
fungi,
facilitating
identification
unique
metabolic
profiles
that
elucidate
their
mechanisms,
host
interactions,
and
treatment
resistance.
This
review
highlights
key
applications
metabolomics
understanding
fungal
metabolites
essential
for
human
virulence,
such
mycotoxins
produced
by
various
species,
Aspergillus
fumigatus
(gliotoxin,
fumagillins)
Candida
species
(phenylethyl
alcohol,
TCA
cycle
metabolites),
secondary
contribute
to
pathogenicity.
It
also
explores
adaptations
fungi
relation
drug
resistance
biofilm
formation,
revealing
alterations
pathways
during
infection,
seen
C.
albicans
auris.
Furthermore,
aids
deciphering
host–pathogen
showcasing
how
like
Cryptococcus
neoformans
modify
metabolism
promote
survival
evade
immune
responses.
The
antifungal
mechanisms
benefited
from
metabolomic
approaches,
identifying
specific
metabolite
patterns
signify
resistance,
Candidozyma
(Candida)
auris,
informing
new
therapeutic
strategies.
integration
with
other
omics
technologies
is
paving
way
comprehensive
biology
pathogenesis.
Such
multi-omics
approaches
are
crucial
discovering
targets
developing
innovative
treatments.
Thus,
purpose
this
provide
an
overview
revolutionizing
our
pathogenesis,
highlight
its
potential
improving
Microbial Biotechnology,
Journal Year:
2024,
Volume and Issue:
17(8)
Published: July 29, 2024
Abstract
We
here
explore
the
potential
of
fungal
genus
Aureobasidium
as
a
prototype
for
microbial
chassis
industrial
biotechnology
in
context
developing
circular
bioeconomy.
The
study
emphasizes
physiological
advantages
,
including
its
polyextremotolerance,
broad
substrate
spectrum,
and
diverse
product
range,
making
it
promising
candidate
cost‐effective
sustainable
processes.
In
second
part,
recent
advances
genetic
tool
development,
well
approaches
up‐scaled
fermentation,
are
described.
This
review
adds
to
growing
body
scientific
literature
on
this
remarkable
fungus
reveals
future
use
biotechnological
industry.
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
72(44), P. 24158 - 24169
Published: Oct. 22, 2024
Laccase,
a
multipurpose
biocatalyst,
is
widely
distributed
across
all
kingdoms
of
life
and
plays
key
role
in
essential
biological
processes
such
as
lignin
synthesis,
degradation,
pigment
formation.
These
functions
are
critical
for
fungal
growth,
plant-pathogen
interactions,
maintenance
soil
health.
Due
to
its
broad
substrate
specificity,
multifunctional
nature,
environmentally
friendly
characteristics,
laccase
employed
catalyst
various
green
chemistry
initiatives.
With
ability
oxidize
diverse
range
phenolic
nonphenolic
compounds,
has
also
been
found
be
useful
food
additive
assessing
quality
parameters.
Ongoing
advancements
research
technology
continually
expanding
the
recognition
laccase's
potential
address
global
environmental,
health,
energy
challenges.
This
review
aims
provide
insights
into
applications
laccases
biotechnology
industry.
BMC Biotechnology,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Jan. 11, 2025
Abstract
Background
This
study
employed
melanin
synthesized
by
Aspergillus
flavus
and
carbonarius
to
inhibit
the
production
of
mycotoxins
bioremediation
heavy
metals
(HMs).
Methods
First,
twenty
fungal
isolates
were
obtained
from
soil
samples,
evaluated
produce
melanin.
The
most
potent
producers
has
undergone
several
confirmatory
experiments,
including,
Dihydroxyphenylalanine
(DOPA)-inhibitor-kojic
acid
pathway
detection,
High-performance
liquid
chromatography
(HPLC),
Fourier-transform
infrared
(FTIR)
Nuclear
magnetic
resonance
(NMR).
Additionally,
culture
conditions
optimized.
antioxidant
activity
was
detected
with
1,1-Diphenyl-2-picrylhydrazyl
(DPPH).
HPLC
used
measure
produced
in
media
supplemented
Molecular
docking
investigated
molecular
interactions
between
through
silico
approaches.
FTIR
Energy-dispersive
X-ray
spectroscopy
(EDX)
utilized
determine
percentage
melanin-chelated
HMs,
an
atomic
absorption
spectrophotometer
(AAS)
detect
HMs
removal
efficiency.
Results
melanin-enriched
medium
(0.3%
0.4%)
exhibited
complete
inhibition
aflatoxin
B1
(AF-B1)
A.
ochratoxin
A
(OTA)
,
respectively.
Furthermore,
showed
effective
HM
efficiency,
increasing
concentration.
efficiency
Cd
+2
Cr
+6
1
mg/mL
49%
63%,
When
concentration
increased
15
mg/mL,
60%
77%,
Conclusion
a
natural
approach
for
production,
using
as
metal-chelating
agent
capability
Further,
provides
significant
evidence
regarding
pipeline,
biotechnological
processes
filamentous
fungi.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(9), P. 1185 - 1185
Published: April 26, 2025
Chitin
and
chitosan
are
valuable
biopolymers
with
various
applications,
ranging
from
food
to
pharmaceuticals.
Traditionally
sourced
crustaceans,
the
rising
demand
for
chitin/chitosan,
paired
development
of
insect
sector,
has
led
exploration
biomass
its
byproducts
as
a
potential
source.
Conventional
processes
rely
on
hazardous
chemicals,
raising
environmental
concerns.
This
critical
review
evaluates
emerging
“greener”
approaches,
including
biological
methods,
green
solvents,
advanced
processing
techniques,
chitin/chitosan
production
insect-derived
materials
such
exuviae
cocoons.
Two
systematic
evaluations
included:
(1)
cross-comparison
chitin
yields
across
life
stages
(e.g.,
up
35.7%
black
soldier
fly
(BSF)
larval
exoskeletons
can
be
obtained)
(2)
stepwise
sustainability
assessment
over
30
extraction
workflows
reported
16
studies.
While
many
labeled
green,
only
few,
bromelain,
lactic
acid
fermentations,
or
NADES-based
processes,
demonstrated
fully
stage.
No
study
achieved
conversion
chitosan,
typically
required
low
fat
content
minimal
pretreatment.
These
findings
will
useful
identify
opportunities
underscore
need
refine
greener
improve
yields,
reduce
impurities,
enable
industrial-scale
production,
while
data
generated.
Frontiers in Fungal Biology,
Journal Year:
2024,
Volume and Issue:
5
Published: Sept. 6, 2024
Carotenoids
produced
by
bacteria,
yeasts,
algae
and
plants
inactivate
Free
Radicals
(FR).
However,
FR
may
carotenoids
even
turn
them
into
free
radicals.
Oxidative
metabolism
is
a
source
of
the
highly
motile
Reactive
Oxygen
Species
(ROS).
To
evaluate
carotenoid
interactions
with
ROS,
yeast
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 30, 2024
Abstract
Temperature
poses
a
unique
challenge
to
ectothermic
species,
as
it
affects
all
biochemical
reactions
in
the
cell
and
causes
physiological
stress.
The
effect
of
temperature
on
an
organism
can
be
described
by
thermal
performance
curve
(TPC),
which
displays
organismal
performance,
such
growth
rate,
function
temperature.
Previous
studies
have
revealed
different
amounts
genetic
variation
trade-offs
TPC
shape
position
within
species
populations.
However,
very
little
is
known
about
architecture
TPCs
level
individual
loci
alleles.
We
asked
what
identity
contributing
TPCs,
do
alleles
exhibit
or
thermodynamic
scaling
across
range?
used
genome-wide
association
mapping
find
influencing
rate
at
temperatures
traits
filamentous
fungus
Neurospora
crassa
.
also
evaluated
directions
magnitudes
allelic
effects
investigate
possible
trade-offs.
observed
both
associations
specific
temperatures,
some
affected
only
low,
intermediate,
high
that
were
shared
multiple
temperatures.
weak
evidence
was
detected,
indicating
evolution
N.
not
constrained
opposite
hot
cold
Our
findings
indicate
contribute
TPCs.
Natural Product Reports,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 18, 2024
Covering:
up
to
2024.For
many
years,
the
value
of
complex
polyketides
lay
in
their
medical
properties,
including
antibiotic
and
antifungal
activities,
with
little
consideration
paid
native
functions.
However,
more
recent
evidence
gathered
from
study
inter-organismal
interactions
has
revealed
influence
these
metabolites
upon
ecological
adaptation
distribution
hosts,
as
well
modes
communication.
The
increasing
number
sequenced
genomes
associated
transcriptomes
also
unveiled
widespread
occurrence
underlying
biosynthetic
enzymes
across
all
kingdoms
life,
important
contributions
they
make
physiological
events
specific
each
organism.
This
review
depicts
diversity
roles
fulfilled
by
type
I
polyketides,
particularly
light
studies
carried
out
during
last
decade,
providing
an
initial
overall
picture
diverse
