Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 423 - 443
Published: Jan. 1, 2024
Language: Английский
Nanomaterials, Journal Year: 2023, Volume and Issue: 13(3), P. 424 - 424
Published: Jan. 19, 2023
Selenium is an important dietary supplement and essential trace element incorporated into selenoproteins with growth-modulating properties cytotoxic mechanisms of action. However, different compounds selenium usually possess a narrow nutritional or therapeutic window low degree absorption delicate safety margins, depending on the dose chemical form in which they are provided to organism. Hence, nanoparticles (SeNPs) emerging as novel diagnostic platform decreased toxicity capacity enhance biological Se-based compounds. Consistent exciting possibilities offered by nanotechnology diagnosis, treatment, prevention diseases, SeNPs useful tools current biomedical research exceptional benefits potential therapeutics, enhanced bioavailability, improved targeting, effectiveness against oxidative stress inflammation-mediated disorders. In view need for developing eco-friendly, inexpensive, simple, high-throughput agents that can also ally theranostic purposes exhibit negligible side effects, biogenic receiving special attention. The present manuscript aims be reference its kind providing readership thorough comprehensive review emphasizes current, yet expanding, field promise hold among selenium-derived products to, eventually, elicit future developments. First, recalls physiological importance oligo-element introduces unique biological, physicochemical, optoelectronic, catalytic Se nanomaterials. Then, it addresses significance nanosizing pharmacological activity (pharmacokinetics pharmacodynamics) cellular interactions SeNPs. Importantly, discusses detail role biosynthesized innovative personalized nanomedicine-based therapies. Finally, this explores ongoing context SARS-CoV-2 pandemic presents key prospects translational nanomedicine.
Language: Английский
Citations
66
Materials, Journal Year: 2023, Volume and Issue: 16(15), P. 5363 - 5363
Published: July 30, 2023
The resistance of microorganisms to antimicrobial drugs is an important problem worldwide. To solve this problem, active searches for components, approaches and therapies are being carried out. Selenium nanoparticles have high potential activity. relevance their application indisputable, which can be noted due the significant increase in publications on topic over past decade. This review research aims provide reader with up-to-date information properties selenium nanoparticles, including susceptible microorganisms, mechanisms action bacteria effect nanoparticle describes most complete antiviral, antibacterial antifungal effects nanoparticles.
Language: Английский
Citations
54
Molecules, Journal Year: 2023, Volume and Issue: 28(24), P. 8125 - 8125
Published: Dec. 15, 2023
Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. "Green" synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers biosynthesis mechanism of bacteria, fungi, algae, plants, including role various biological substances processes reducing selenium compounds SeNPs their further packaging. Modern information approaches possible biomedical use presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, other properties, as well mechanisms these processes, that have important potential therapeutic value.
Language: Английский
Citations
44
Nanoscale Advances, Journal Year: 2024, Volume and Issue: 6(7), P. 1800 - 1821
Published: Jan. 1, 2024
Here, we explored the recent development of MOF-based nanomaterials for biomedical applications. not only show excellent bio-imaging and biosensing performance but also can be well designed as bio-carriers in drug delivery.
Language: Английский
Citations
37
Resources, Journal Year: 2024, Volume and Issue: 13(6), P. 70 - 70
Published: May 26, 2024
The synthesis of inorganic nanoparticles for diverse applications is an active research area that involves physical and chemical methods, which typically are expensive, involve hazardous reagents, use complex equipment conditions, consume large amounts time energy. Thus, green methods have emerged as eco-friendly easy alternatives nanoparticle synthesis, particularly the plant-based extracts from fruit juice, leaves, seeds, peel, stem, barks, roots, act reducing, capping, stabilizing agents, contributing to Sustainable Development Goals circular economy principles. Therefore, been synthesized using extracts, including gold, silver, titanium dioxide, zinc, copper, platinum, zirconium, iron, selenium, magnesium, nickel, sulfur, cobalt, palladium, indium nanoparticles, exhibit different biological activities such antioxidant, antimicrobial, dye degradation, cytotoxic, analgesic, sedative, wound-healing, skin protection, sensor development, plant-growth-promoting effects. this review summarizes advantages limitations agents synthesis.
Language: Английский
Citations
32
Polymers, Journal Year: 2022, Volume and Issue: 14(15), P. 2994 - 2994
Published: July 24, 2022
The medicinal administration of Aloe vera gel has become promising in pharmaceutical and cosmetic applications particularly with the development nanotechnology concept. Nowadays, effective H. pylori treatment is a global problem; therefore, natural products nanopolymers such as chitosan nanoparticles (CSNPs) could represent novel strategy for gastric infection pylori. HPLC analysis A. indicated presence chlorogenic acid main constituent (1637.09 µg/mL) other compounds pyrocatechol µg/mL), catechin (1552.92 naringenin (528.78 rutin (194.39 quercetin (295.25 cinnamic (37.50 µg/mL). CSNPs incorporated were examined via TEM, indicating mean sizes 83.46 nm 36.54 nm, respectively. FTIR spectra showed various different functional groups CSNPs, gel, CSNPs. Two strains inhibited using inhibition zones 16 16.5 mm, while exhibited highest 28 30 resistant sensitive strains, minimal inhibitory concentration (MIC) was 15.62 3.9 µg/mL, bactericidal (MBC) 15.60 7.8 µg/mL MBC/MIC 1 2 indexes respectively, against resistance strain. DPPH Scavenging (%) antioxidant activity an IC50 138.82 μg/mL A.vera extract, 81.7 when enhanced hemolysis compared to alone. Molecular docking studies through interaction components crystal structure (4HI0) protein supported results anti-H. activity.
Language: Английский
Citations
65
RSC Advances, Journal Year: 2022, Volume and Issue: 12(41), P. 26603 - 26619
Published: Jan. 1, 2022
In this research, we reported for the first time simple incorporation of antibiotic cefotaxime (CFM) with Ag NPs, Se and bimetallic Ag–Se NPs by gamma rays; as a promising cost-effective, eco-friendly method.
Language: Английский
Citations
64
Biomass Conversion and Biorefinery, Journal Year: 2022, Volume and Issue: 14(22), P. 28253 - 28270
Published: Nov. 11, 2022
Abstract The goal of the current work was to investigate antibacterial, antibiofilm, anticancer, and antioxidant opportunities silver gold nanoparticles (AgNPs AuNPs) synthesized utilizing a new fungus strain called Fusarium pseudonygamai TB-13c. With aid UV, HR-TEM, FTIR, SEM, XRD, NPs’ creation examined. For AgNPs AuNPs, mycosynthesized highest peak plasmon band seen at around 420 540 nm, respectively. ranged in size from 5 20 whereas AuNPs 8 60 nm. were spherical form. AgNPs, angles 38.42°, 44.56°, 64.66°, 77.75°; for 38.56°, 44.74°, 64.87°, 77.85°. antibacterial efficiency evaluated against Klebsiella pneumoniae , Pseudomonas aeruginosa methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant (MRSA). In particular, outperformed their ability combat pathogenic microorganisms. Furthermore, antibiofilm study that shown had activity more than AgNPs. Interestingly, applying DPPH procedure these noble metallic NPs activity, which IC 50 38.2 μg/ mL 180 AuNPs. modification cells evident cytotoxicity evaluation findings as change usual shape, partially or completely loss monolayer, granulation, shrinkage, cell rounding with normal vero 695.34 μg/mL 631.66 respectively, whilst cancer (Mcf7) 204.07 206.95 combined results show there is clear flexible biological use less toxic chemotherapeutic agents.
Language: Английский
Citations
64
Life, Journal Year: 2022, Volume and Issue: 12(9), P. 1331 - 1331
Published: Aug. 28, 2022
The toxicity of the ecosystem has increased recently as a result industrial wastewater loaded with organic contaminants, including methylene blue (MB), which exerts serious damage to environment. Thus, present work aims green synthesis silver nanoparticles (Ag-NPs) and evaluate their degradability notorious MB dye, well antimicrobial activities. Ag-NPs were synthesized by Cytobacillus firmus extract fully characterized UV-vis, TEM, DLS, XRD, FTIR. showed good antibacterial antifungal activities against Escherichia coli ATCC 25922, Enterococcus feacalis 29212, Pseudomonas aeruginosa 27853, Staphylococcus aureus 25923, Candida albicans 90028. Moreover, exhibited high biodegradability level (98%) dye after 8 h co-incubation in presence sunlight. Additionally, phytotoxicity treated dye-contaminated water sample germination Vicia faba compared non-treated solution. In conclusion, herein biosynthesized demonstrated its feasibility purification contaminated from microbes probability reusing purified for agricultural purposes.
Language: Английский
Citations
52
Applied Biochemistry and Biotechnology, Journal Year: 2023, Volume and Issue: 195(10), P. 5753 - 5776
Published: Jan. 27, 2023
Language: Английский
Citations
38