Applied Materials Today, Journal Year: 2024, Volume and Issue: 40, P. 102335 - 102335
Published: July 27, 2024
Language: Английский
Materials, Journal Year: 2023, Volume and Issue: 16(15), P. 5363 - 5363
Published: July 30, 2023
The resistance of microorganisms to antimicrobial drugs is an important problem worldwide. To solve this problem, active searches for components, approaches and therapies are being carried out. Selenium nanoparticles have high potential activity. relevance their application indisputable, which can be noted due the significant increase in publications on topic over past decade. This review research aims provide reader with up-to-date information properties selenium nanoparticles, including susceptible microorganisms, mechanisms action bacteria effect nanoparticle describes most complete antiviral, antibacterial antifungal effects nanoparticles.
Language: Английский
Citations
54
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(5), P. 2600 - 2600
Published: Feb. 23, 2024
Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance between oxygen and nitrogen species in the body its ability to neutralize them. These generated by both internal external factors can damage cellular lipids, proteins, DNA. Antioxidants prevent or slow down oxidation process interrupting transfer of electrons substances agents. This is particularly important at level because reactions lead formation FR contribute various diseases. As we age, RS accumulates leads organ dysfunction age-related disorders. Polyphenols; vitamins A, C, E; selenoproteins possess antioxidant properties may have a role preventing treating certain human diseases associated with RS. In this review, explore current evidence on potential benefits dietary supplementation investigate intricate connection SIRT1, crucial regulator aging longevity; transcription factor NRF2; polyphenols, vitamins, selenium. Finally, discuss positive effects molecules, such as reducing RS, their slowing several
Language: Английский
Citations
37
Next Nanotechnology, Journal Year: 2024, Volume and Issue: 7, P. 100102 - 100102
Published: Sept. 11, 2024
Language: Английский
Citations
21
Frontiers in Chemistry, Journal Year: 2023, Volume and Issue: 11
Published: Sept. 22, 2023
Biogenic nanoparticle production is in demand as it secure, has great promise, and environmental friendly. This study aimed at green synthesis, characterization, evaluation of Terminalia arjuna selenium nanoparticles (TA-SeNPs) for their antioxidant, antibacterial, anticancer activities, incorporation gel biomedical applications. The bio-reduction attributes the T. (TA) bark extract were utilized to fabricate nanoparticles. TA abundant phenolics (193.63 ± 1.61 mg gallic acid equivalents/g), flavonoids (88.23 0.39 quercetin tannins (109.46 1.16 catechin which perform effective capping stabilizing agents, thus enabling fabrication stable SeNPs. TA-SeNPs was corroborated by UV-visible spectra, exhibited surface plasmon resonance 291 nm. Transmission electron microscopy (TEM) scanning (SEM) demonstrated nano-sized spherical with an average diameter ranging from 100 150 Zeta potential analysis revealed that negatively charged (-26.1 mV). X-ray diffraction presented amorphous a quantification 82.36 10.2 μg/mL resulting ICP-AES. IC50 45.18 0.11 DPPH assay 66.51% reducing power capacity values indicated possessed excellent radical scavenging efficacy. Moreover, broad spectrum antimicrobial activity against pathogens. Additionally, dose-dependent cytotoxic effect on MCF-7 breast cancer cell line, 23.41 μg/mL. Furthermore, TA-SeNP-incorporated showed spreadability, extrudability, consistency retention properties hydrophilic contact angle. As outcome, offer possibility formulation growth sustainably designed SeNPs can be produced, conserved, marketed securely across globe.
Language: Английский
Citations
30
International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 662, P. 124535 - 124535
Published: Aug. 1, 2024
The advancements in nanotechnology, pharmaceutical sciences, and healthcare are propelling the field of theranostics, which combines therapy diagnostics, to new heights; emphasizing emergence selenium nanoparticles (SeNPs) as versatile theranostic agents. This comprehensive update offers a holistic perspective on recent developments synthesis applications SeNPs, underscoring their growing importance nanotechnology healthcare. SeNPs have shown significant potential multiple domains, including antioxidant, anti-inflammatory, anticancer, antimicrobial, antidiabetic, wound healing, cytoprotective therapies. review highlights adaptability biocompatibility crucial for advanced disease detection, monitoring, personalized treatment. Special emphasis is placed green techniques, eco-friendly cost-effective benefits biosensing, imaging therapeutic applications. Additionally, appraisal scrutinizes progressive trends smart stimuli-responsive conferring role innovative solutions management diagnostics. Despite promising prophylactic potential, also present several challenges, particularly regarding toxicity concerns. These challenges implications clinical translation thoroughly explored, providing balanced view current state prospects
Language: Английский
Citations
15
Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 472, P. 134491 - 134491
Published: May 1, 2024
Language: Английский
Citations
14
Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 51(1)
Published: May 25, 2024
Abstract Selenium nanoparticles (SeNPs) are an appealing carrier for the targeted delivery. The selenium gaining global attention because of potential therapeutic applications in several diseases e.g., rheumatoid arthritis (RA), inflammatory bowel disease (IBD), asthma, liver, and various autoimmune disorders like psoriasis, cancer, diabetes, a variety infectious diseases. Despite fact still there is no recent literature that summarises SeNPs. There some challenges need to be addressed finding targets SeNPs diseases, functionalization techniques utilized increase SeNP’s stability while facilitating wide drug-loaded SeNP distribution tumor areas preventing off-target impacts focus on understanding more about aspects better science behind it. Keeping mind we have focused this gap try summarize all key therapies cancer treatment numerous strategies. We also advancements methodologies mechanisms biomedical applications, particularly anticancer, anti-inflammatory, anti-infection therapeutics. Based our observation found could potentially useful suppressing viral epidemics, ongoing COVID-19 pandemic, complement their antibacterial antiparasitic uses. significant nanoplatforms with desirable properties clinical translation. Graphical
Language: Английский
Citations
14
Materials Advances, Journal Year: 2024, Volume and Issue: 5(9), P. 3602 - 3628
Published: Jan. 1, 2024
Selenium (Se) is a paramount micronutrient, indispensable for the holistic health of humans, animals, and microorganisms.
Language: Английский
Citations
13
Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 468, P. 133850 - 133850
Published: Feb. 20, 2024
Language: Английский
Citations
10
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 265, P. 130747 - 130747
Published: March 12, 2024
Language: Английский
Citations
10