Marine Macroalgae: Sustainable Practices and Environmental Impact DOI
Nour Sh. El‐Gendy, Hussein N. Nassar

Royal Society of Chemistry eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 183 - 219

Published: Nov. 29, 2024

The blue bioeconomy represents a sustainable pathway to utilizing marine resources for economic growth and environmental stewardship. Within the framework, this chapter aims provide insights into leveraging macroalgae development innovation in bioeconomy. It gives brief overview of types diversity (seaweeds) besides their ecological importance. explores wide range bioactive compounds that produce, including metabolites, polysaccharides, lipids, pigments. delves potential as cradles value-added products biofuels. Additionally, examines importance practices, considerations, challenges associated with commercialization.

Language: Английский

Bioactivity and Bioavailability of Carotenoids Applied in Human Health: Technological Advances and Innovation DOI Open Access
Tomás Gabriel Bas

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7603 - 7603

Published: July 11, 2024

This article presents a groundbreaking perspective on carotenoids, focusing their innovative applications and transformative potential in human health medicine. Research jointly delves deeper into the bioactivity bioavailability of revealing therapeutic uses technological advances that have to revolutionize medical treatments. We explore pioneering which carotenoids are used treat chronic diseases such as cancer, cardiovascular disease, age-related macular degeneration, offering novel protective mechanisms benefits. Our study also shows cutting-edge innovations carotenoid extraction bioavailability, including development supramolecular carriers advanced nanotechnology, dramatically improve absorption efficacy these compounds. These not only ensure consistent quality but tailor therapies each patient's needs, paving way for personalized By integrating latest scientific discoveries techniques, this research provides prospective clinical establishing new benchmark future studies field. findings underscore importance optimizing extraction, administration, bioactivity, methods develop more effective, targeted, treatments, thus visionary insight modern practices.

Language: Английский

Citations

12

Algae Food Products as a Healthcare Solution DOI Creative Commons
Joana O. Tavares, João Cotas, Ana Valado

et al.

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(11), P. 578 - 578

Published: Nov. 5, 2023

Diseases such as obesity; cardiovascular diseases high blood pressure, myocardial infarction and stroke; digestive celiac disease; certain types of cancer osteoporosis are related to food. On the other hand, world’s population increases, ability current food production system produce consistently is at risk. As a result, intensive agriculture has contributed climate change major environmental impact. Research is, therefore, needed find new sustainable sources. One most promising sources raw materials macroalgae. Algae crucial solving this nutritional deficiency because they abundant in bioactive substances that have been shown combat hyperglycemia, diabetes, obesity, metabolic disorders, neurodegenerative diseases. Examples these include polysaccharides alginate, fucoidan, agar carrageenan; proteins phycobiliproteins; carotenoids β-carotene fucoxanthin; phenolic compounds; vitamins minerals. Seaweed already considered nutraceutical since it higher protein values than legumes soy becoming increasingly common. compounds extracted from seaweed used industry thickening agents stabilizers improve quality final product extend its shelf life; also demonstrated antidiabetic effects. Among present macroalgae, compounds, pigments, fatty acids stand out due their different properties, antidiabetics, antimicrobials antioxidants, which important treatment or control cholesterol, hyperglycemia That said, there some studies macroalgae (red, green brown) incorporated into foods, but on gluten-free products still scarce, only potential use for type considered. Considering aforementioned issues, review aims analyze how can be foods supplement, well describe contain, beneficial properties human health. In way, macroalgae-based eminent diseases, disease, more common diabetes cholesterol complications, seen.

Language: Английский

Citations

19

Gut–Liver–Pancreas Axis Crosstalk in Health and Disease: From the Role of Microbial Metabolites to Innovative Microbiota Manipulating Strategies DOI Creative Commons
Giada Marroncini,

Laura Naldi,

Serena Martinelli

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(7), P. 1398 - 1398

Published: June 24, 2024

The functions of the gut are closely related to those many other organs in human body. Indeed, microbiota (GM) metabolize several nutrients and compounds that, once released bloodstream, can reach distant organs, thus influencing metabolic inflammatory tone host. main microbiota-derived metabolites responsible for modulation endocrine responses short-chain fatty acids (SCFAs), bile glucagon-like peptide 1 (GLP-1). These molecules (i) regulate pancreatic hormones (insulin glucagon), (ii) increase glycogen synthesis liver, (iii) boost energy expenditure, especially skeletal muscles brown adipose tissue. In words, they critical maintaining glucose lipid homeostasis. GM dysbiosis, imbalance microbiota-related products affect proper functions, including gut–liver–pancreas axis (GLPA). addition, dysbiosis contribute onset some diseases such as non-alcoholic steatohepatitis (NASH)/non-alcoholic liver disease (NAFLD), hepatocellular carcinoma (HCC), type 2 diabetes (T2D). this review, we explored roles their involvement progression these diseases. detailed microbiota-modulating strategies that could improve diseases’ development by restoring healthy balance GLPA.

Language: Английский

Citations

7

Seaweeds as Nutraceutical Elements and Drugs for Diabetes Mellitus: Future Perspectives DOI Creative Commons
João Cotas, Silvia Lomartire, Leonel Pereira

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(4), P. 168 - 168

Published: April 10, 2024

Diabetes mellitus is a chronic metabolic condition marked by high blood glucose levels caused inadequate insulin synthesis or poor use. This affects millions of individuals worldwide and linked to variety consequences, including cardiovascular disease, neuropathy, nephropathy, retinopathy. therapy now focuses on controlling through lifestyle changes, oral medicines, injections. However, these therapies have limits may not successfully prevent treat diabetic problems. Several marine-derived chemicals previously demonstrated promising findings as possible antidiabetic medicines in preclinical investigations. Peptides, polyphenols, polysaccharides extracted from seaweeds, sponges, other marine species are among them. As result, natural products the potential be rich source innovative multitargeted medications for diabetes prevention treatment, well associated complications. Future research should focus chemical creatures mechanisms action order find new maximize their therapeutic potential. Based investigations, this review next step seaweed applications diabetes, highlighting bioactivities seaweeds treatment illness.

Language: Английский

Citations

6

Exploring algal diversity for enhanced nutrition: Implications for human health and sustainability DOI

M. Maghimaa,

Suresh Sagadevan, Is Fatimah

et al.

Algal Research, Journal Year: 2025, Volume and Issue: 86, P. 103907 - 103907

Published: Jan. 10, 2025

Language: Английский

Citations

0

The assessment of the safety and toxicity of the functional foods and nutraceuticals DOI
Elahesadat Hosseini, Rafael Audino Zambelli,

Pantea Ghalambor

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 315 - 335

Published: Jan. 1, 2025

Language: Английский

Citations

0

Metabolic profiling and antidiabetic potential of Oedogonium angustistomum, Ulothrix variabilis, and Mougeotia pulchella and their peptides targeting α-amylase and α-glucosidase: In vitro and in silico approaches DOI
Sruthy Elsa Shibu,

Edathiruthi Kottukkal Chandran Baiju,

Singamoorthy Amalraj

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140877 - 140877

Published: Feb. 1, 2025

Language: Английский

Citations

0

Plant genetic transformation: achievements, current status and future prospects DOI Creative Commons
Peilin Wang, Huan Si, Chen‐Hui Li

et al.

Plant Biotechnology Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Regeneration represents a fundamental biological process wherein an organism's tissues or organs repair and replace themselves following damage environmental stress. In plant systems, injured tree branches can regenerate adventitious buds develop new crowns through propagation techniques like cuttings canopy pruning, while transgenic plants emerge via tissue culture in genetic engineering processes intimately connected to regeneration mechanisms. The advancement of technology is critical for addressing complex dynamic climate challenges, ultimately ensuring global agricultural sustainability. This review comprehensively synthesizes the latest transformation technologies, including systems across woody, herbaceous algal species, organellar modifications, crucial factors facilitating Agrobacterium-mediated transformations, intricate hormonal networks regulating regeneration, comparative analyses transient approaches marker gene dynamics throughout processes. Ultimately, offers novel perspectives on current bottlenecks proposes future research trajectories.

Language: Английский

Citations

0

In vitro and in silico pharmaco-nutritional assessments of some lesser-known Nigerian nuts: Persea americana, Tetracarpidium conophorum, and Terminalia catappa DOI Creative Commons

E. Eyong,

Iwara Arikpo Iwara, Eyuwa Ignatius Agwupuye

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(4), P. e0319756 - e0319756

Published: April 9, 2025

Together with their nutritional qualities, the biosafety, antidiabetic, antioxidant, and anti-inflammatory effects of Tetracarpidium conophorum nuts, Persea americana seeds, Terminalia cattapa kernels were evaluated in vitro silico. RBC membrane stabilisation for characteristics, antioxidant activities by ABTS, DPPH, H2O2, nitric oxide scavenging assays, α-glucosidase α-amylase inhibitory assays conducted used to evaluate anti-diabetic activity. With an IC50 value 208 μg/mL , P. showed maximum amount inhibition, according results, while T. catappa a somewhat lower degree inhibition at 236 . exhibited highest 312 µg/mL. strongest DPPH radical activity, ABTS effectiveness neutralising hydrogen peroxide. In tests using human red blood cells, hemolysis. While higher concentrations copper, manganese, potassium, calcium, magnesium concentrations. had considerably levels ash, proteins, lipids, carbohydrates than which quantity crude fibre, proximate analysis. Molecular docking experiments have revealed that plant extracts from americana, substantial binding affinities towards amylase. Pseudococaine, M-(1-methylbutyl) phenylmethylcarbamate, o-xylene, 1-deoxynojirimycin four compounds those acarbose. Acarbose nitrate not as compatible scores compared dimethyl phthalate, pseudococaine, M-(1-Methylbutyl)phenyl methylcarbamate, 2-chloro-3-oxohexanedioic acid, methyl 2-chloro-5-nitrobenzoate. These results suggest these hold great potential creation therapeutic medications specifically target oxidative stress-related diseases like diabetes.

Language: Английский

Citations

0

Efficacy of the marine red alga Laurencia papillosa extract on alloxan stimulated hyperglycemic activity in male wistar albino rats DOI
Mostafa M. El‐Sheekh,

Naglaa Kasem,

Hesham M. Alsoghier

et al.

Bioactive Carbohydrates and Dietary Fibre, Journal Year: 2024, Volume and Issue: 31, P. 100403 - 100403

Published: Jan. 21, 2024

Language: Английский

Citations

2