Advanced Engineering Materials,
Journal Year:
2021,
Volume and Issue:
23(10)
Published: Sept. 20, 2021
Increasing
demand
for
customized
implants
and
tissue
scaffolds
requires
advanced
biomaterials
fabricating
processes
three‐dimensional
(3D)
structures
that
resemble
the
complexity
of
extracellular
matrix
(ECM).
Lately,
biofabrication
approaches
such
as
cell‐laden
(soft)
hydrogel
3D
printing
(3DP)
have
been
increasing
interest
in
development
functional
environments
similar
to
natural
tissues
organs.
Hydrogels
biological
ECMs
can
provide
mechanical
support
signaling
cues
cells
control
their
behavior.
Although
capability
hydrogels
produce
artificial
regulate
cellular
behavior,
one
major
drawbacks
working
with
is
inferior
properties.
Therefore,
keeping
enhancing
integrity
fabricated
has
become
an
essential
matter
structures.
Herein,
3D‐printed
hydrogel‐based
nanocomposites
(NCs)
are
evaluated
systematically
terms
introducing
novel
techniques
3DP
materials,
properties,
biomedical
applications.
Gels,
Journal Year:
2022,
Volume and Issue:
8(3), P. 179 - 179
Published: March 14, 2022
Three-dimensional
(3D)
printing
is
well
acknowledged
to
constitute
an
important
technology
in
tissue
engineering,
largely
due
the
increasing
global
demand
for
organ
replacement
and
regeneration.
In
3D
bioprinting,
which
a
step
ahead
of
biomaterial
printing,
ink
employed
impregnated
with
cells,
without
compromising
printability.
This
allows
immediate
scaffold
cellularization
generation
complex
structures.
The
use
cell-laden
inks
or
bio-inks
provides
opportunity
enhanced
cell
differentiation
fabrication
Recognizing
importance
such
bio-inks,
current
study
comprehensively
explores
state
art
utilization
based
on
natural
polymers
(biopolymers),
as
cellulose,
agarose,
alginate,
decellularized
matrix,
bioprinting.
Discussions
regarding
progress
techniques
approaches
bioprinting
polymers,
limitations
prospects
concerning
future
trends
human-scale
are
also
presented.
Asian Journal of Pharmaceutical Sciences,
Journal Year:
2023,
Volume and Issue:
18(3), P. 100812 - 100812
Published: April 27, 2023
Biopolymers
are
promising
environmentally
benign
materials
applicable
in
multifarious
applications.
They
especially
favorable
implantable
biomedical
devices
thanks
to
their
excellent
unique
properties,
including
bioactivity,
renewability,
bioresorbability,
biocompatibility,
biodegradability
and
hydrophilicity.
Additive
manufacturing
(AM)
is
a
flexible
intricate
technology,
which
widely
used
fabricate
biopolymer-based
customized
products
structures
for
advanced
healthcare
systems.
Three-dimensional
(3D)
printing
of
these
sustainable
applied
functional
clinical
settings
wound
dressing,
drug
delivery
systems,
medical
implants
tissue
engineering.
The
present
review
highlights
recent
advancements
different
types
biopolymers,
such
as
proteins
polysaccharides,
employed
develop
by
using
extrusion,
vat
polymerization,
laser
inkjet
3D
techniques
addition
normal
bioprinting
four-dimensional
(4D)
techniques.
This
also
incorporates
the
influence
nanoparticles
on
biological
mechanical
performances
3D-printed
scaffolds.
work
addresses
current
challenges
well
future
developments
friendly
polymeric
manufactured
through
AM
Ideally,
there
need
more
focused
research
adequate
blending
biodegradable
biopolymers
achieving
useful
results
targeted
areas.
We
envision
that
composites
have
potential
revolutionize
sector
near
future.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(3), P. 807 - 807
Published: March 1, 2023
Chitosan
is
a
chitin-derived
biopolymer
that
has
shown
great
potential
for
tissue
regeneration
and
controlled
drug
delivery.
It
numerous
qualities
make
it
attractive
biomedical
applications
such
as
biocompatibility,
low
toxicity,
broad-spectrum
antimicrobial
activity,
many
others.
Importantly,
chitosan
can
be
fabricated
into
variety
of
structures
including
nanoparticles,
scaffolds,
hydrogels,
membranes,
which
tailored
to
deliver
desirable
outcome.
Composite
chitosan-based
biomaterials
have
been
demonstrated
stimulate
in
vivo
the
repair
various
tissues
organs,
but
not
limited
to,
bone,
cartilage,
dental,
skin,
nerve,
cardiac,
other
tissues.
Specifically,
de
novo
formation,
resident
stem
cell
differentiation,
extracellular
matrix
reconstruction
were
observed
multiple
preclinical
models
different
injuries
upon
treatment
with
formulations.
Moreover,
proven
efficient
carriers
medications,
genes,
bioactive
compounds
since
they
maintain
sustained
release
these
therapeutics.
In
this
review,
we
discuss
most
recently
published
organ
well
delivery
Advanced Engineering Materials,
Journal Year:
2023,
Volume and Issue:
25(21)
Published: Aug. 29, 2023
Stimuli‐responsive
polymers
(SRPs)
are
special
types
of
soft
materials,
which
have
been
extensively
used
for
developing
flexible
actuators,
robots,
wearable
devices,
sensors,
self‐expanding
structures,
and
biomedical
thanks
to
their
ability
change
shapes
functional
properties
in
response
external
stimuli
including
light,
humidity,
heat,
pH,
electric
field,
solvent,
magnetic
field
or
combinations
two
more
these
stimuli.
In
recent
years,
additive
manufacturing
(AM)
aka
3D
printing
technology
SRPs,
also
known
as
4D
printing,
has
gained
phenomenal
attention
different
engineering
fields,
its
unique
develop
complex,
personalized,
innovative
undergo
twisting,
elongating,
swelling,
rolling,
shrinking,
bending,
spiraling,
other
complex
morphological
transformations.
Herein,
an
effort
made
provide
insightful
information
about
the
AM
techniques,
type
applications
including,
but
not
limited
tissue
engineering,
bionics,
construction,
smart
textiles.
This
article
incorporates
current
challenges
prospects,
hoping
basis
utilization
this
fields.
It
is
expected
that
amalgamation
with
SRPs
would
unparalleled
advantages
arenas.
ACS Biomaterials Science & Engineering,
Journal Year:
2023,
Volume and Issue:
9(5), P. 2181 - 2202
Published: April 10, 2023
Over
the
past
few
decades,
chitosan
(CS)
has
gained
attention
of
researchers
investigating
newer
biomaterial-based
carriers
for
drugs
in
pharmaceutical
and
biomedical
research.
Combined
with
its
nontoxic
behavior,
biodegradability,
biocompatibility,
found
widespread
applications
fields
drug
delivery,
tissue
engineering,
cosmetics.
As
a
novel
carrier,
is
regarded
as
one
promising
biomaterials
industry.
The
extensive
use
this
cationic
biopolysaccharide
delivery
therapeutic
agents
brought
limitations
into
limelight.
Various
chemical
modifications
can
minimize
these
improve
efficacy
carrier.
effectiveness
several
chemically
modified
derivatives,
including
trimethyl
chitosan,
thiolated
PEGylated
other
been
investigated
by
many
controlled
target
specific
therapeutics.
derivatives
exhibited
greater
importance
current
scenario
on
due
to
their
solubility
wide
range
media
along
interaction
pharmaceutically
active
ingredients.
Chitosan
have
also
attracted
fields,
wound
healing,
hyperthermia
therapy,
bioadhesives.
present
review
narrates
sources
common
physicochemical
properties
important
synthetic
obtain
chitosans
target-specific
applications.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(1), P. 145 - 145
Published: Jan. 7, 2022
3D
printing,
or
additive
manufacturing,
has
gained
considerable
interest
due
to
its
versatility
regarding
design
as
well
in
the
large
choice
of
materials.
It
is
a
powerful
tool
field
personalized
pharmaceutical
treatment,
particularly
crucial
for
pediatric
and
geriatric
patients.
Polysaccharides
are
abundant
inexpensive
natural
polymers,
that
already
widely
used
food
industry
excipients
cosmetic
formulations.
Due
their
intrinsic
properties,
such
biocompatibility,
biodegradability,
non-immunogenicity,
etc.,
polysaccharides
largely
investigated
matrices
drug
delivery.
Although
an
increasing
number
interesting
reviews
on
manufacturing
delivery
being
published,
there
gap
concerning
printing
polysaccharides.
In
this
article,
we
will
review
recent
advances
focused
applications.
Among
family
polysaccharides,
present
focus
cellulose
derivatives,
chitosan
sodium
alginate,
printed
by
fused
deposition
modeling
extrusion-based
printing.
Giant,
Journal Year:
2023,
Volume and Issue:
17, P. 100209 - 100209
Published: Nov. 15, 2023
Additive
manufacturing
(AM)
aka
three-dimensional
(3D)
printing
has
been
a
well-established
and
unparalleled
technology,
which
is
expanding
the
boundaries
of
materials
science
exhibiting
an
enormous
potential
to
fabricate
intricate
geometries
for
healthcare,
electronics,
construction
sectors.
In
contemporary
era,
combination
AM
technology
stimuli-responsive
hydrogels
(SRHs)
helps
create
dynamic
functional
structures
with
extreme
accuracy,
are
capable
changing
their
shape,
functional,
or
mechanical
properties
in
response
environmental
cues
such
as
humidity,
heat,
light,
pH,
magnetic
field,
electric
etc.
3D
SRHs
permits
creation
on-demand
dynamically
controllable
shapes
excellent
control
over
various
self-repair,
self-assembly,
multi-functionality,
These
accelerate
researchers
think
unthinkable
applications.
Additively
manufactured
objects
have
shown
applications
like
tissue
engineering,
drug
delivery,
soft
robots,
sensors,
other
biomedical
devices.
The
current
review
provides
recent
progress
SRHs,
more
focus
on
techniques,
stimuli
mechanisms,
shape
morphing
behaviors,
Finally,
trends
future
roadmap
additively
smart
different
also
presented,
will
be
helpful
research.
This
holds
great
promise
providing
fundamental
knowledge
about
diverse