Biopolymer: A Sustainable Material for Food and Medical Applications

Polymers, Journal Year: 2022, Volume and Issue: 14(5), P. 983 - 983

Published: Feb. 28, 2022

Biopolymers are a leading class of functional material suitable for high-value applications and great interest to researchers professionals across various disciplines. Interdisciplinary research is important understand the basic applied aspects biopolymers address several complex problems associated with good health well-being. To reduce environmental impact dependence on fossil fuels, lot effort has gone into replacing synthetic polymers biodegradable materials, especially those derived from natural resources. In this regard, many types or have been developed meet needs ever-expanding applications. These currently used in food expanding their use pharmaceutical medical industries due unique properties. This review focuses uses industry provides future outlook biopolymer industry.

Language: Английский

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3D printed hydrogel for articular cartilage regeneration

Composites Part B Engineering, Journal Year: 2022, Volume and Issue: 237, P. 109863 - 109863

Published: April 1, 2022

Language: Английский

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Use of Bombyx mori silk fibroin in tissue engineering: From cocoons to medical devices, challenges, and future perspectives

Biomaterials Advances, Journal Year: 2022, Volume and Issue: 139, P. 212982 - 212982

Published: June 11, 2022

Language: Английский

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Hydrogels for Wound Dressings: Applications in Burn Treatment and Chronic Wound Care

Journal of Composites Science, Journal Year: 2025, Volume and Issue: 9(3), P. 133 - 133

Published: March 13, 2025

Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.

Language: Английский

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Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering

Nanomaterials, Journal Year: 2021, Volume and Issue: 11(9), P. 2337 - 2337

Published: Sept. 8, 2021

In recent years, many promising nanotechnological approaches to biomedical research have been developed in order increase implementation of regenerative medicine and tissue engineering clinical practice. the meantime, use nanomaterials for regeneration diseased or injured tissues is considered advantageous most areas medicine. particular, treatment cardiovascular, osteochondral neurological defects, but also recovery functions other organs such as kidney, liver, pancreas, bladder, urethra wound healing, are increasingly being that serve scaffolds, mimic extracellular matrix promote adhesion differentiation cells. This review focuses on latest developments medicine, which iron oxide nanoparticles (IONPs) play a crucial role cell therapy. IONPs not only enabling non-invasive observation methods monitor therapy, can accelerate enhance regeneration, either thanks their inherent magnetic properties by functionalization with bioactive therapeutic compounds, drugs, enzymes growth factors. addition, presence fields direct IONP-labeled cells specifically site action induce into specific type through mechanotransduction.

Language: Английский

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Silk Fibroin-Based Therapeutics for Impaired Wound Healing

Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(3), P. 651 - 651

Published: March 16, 2022

Impaired wound healing can lead to local hypoxia or tissue necrosis and ultimately result in amputation even death. Various factors influence the environment, including bacterial fungal infections, different disease states, desiccation, edema, systemic viral infections such as COVID-19. Silk fibroin, fibrous structural-protein component silk, has emerged a promising treatment for these impaired processes by promoting functional regeneration. fibroin's dynamic properties allow customizable nanoarchitectures, which be tailored effectively treating several impairments. Different forms of silk fibroin include nanoparticles, biosensors, scaffolds, dressings, novel drug-delivery systems. combined with other biomaterials, chitosan microRNA-bound cerium oxide nanoparticles (CNP), have synergistic effect on improving healing. This review focuses applications silk-fibroin-based nanotechnology process; here we discuss scaffold, topical solution, biosensor, nanoparticle.

Language: Английский

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Chitosan/Silk Fibroin Materials for Biomedical Applications—A Review

Polymers, Journal Year: 2022, Volume and Issue: 14(7), P. 1343 - 1343

Published: March 26, 2022

This review provides a report on recent advances in the field of chitosan (CTS) and silk fibroin (SF) biopolymer blends as new biomaterials. Chitosan are widely used to obtain However, materials based these two biopolymers have not been summarized paper yet. As can attract both academic industrial attention, we propose this showcase latest achievements area. In review, literature regarding preparation properties their has reviewed.

Language: Английский

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Ancient fibrous biomaterials from silkworm protein fibroin and spider silk blends: Biomechanical patterns

Acta Biomaterialia, Journal Year: 2022, Volume and Issue: 153, P. 38 - 67

Published: Sept. 17, 2022

Silkworm silk protein fibroin and spider spidroin are known biocompatible natural biodegradable polymers in biomedical applications. The presence of β-sheets conformation improves their mechanical properties. strength toughness pure recombinant silkworm relatively low due to reduced molecular weight. Hence, blending is the foremost approach recent studies optimize spidroin's As summarised present review, numerous research investigations evaluate synthetic polymers. effects with on properties discussed this review article. Indeed, combining changes structure, fine-tuning blends' STATEMENT OF SIGNIFICANCE: proteins (silk spidroin) having different types Their biological may be tuned through various strategies such as blending, conjugating cross-linking. Blending most common method modify demand. This article aims categorize Increased polarity hydrophilicity end hydrogen bonding triggered conformational change blends. effect compound has been relation structural biomaterials. These have categorized combinatorial, synergistic indirect impact outlook guides us choose compounds mindfully mixing affects biochemical biophysical characteristics

Language: Английский

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A Comprehensive Review on Silk Fibroin as a Persuasive Biomaterial for Bone Tissue Engineering

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(3), P. 2660 - 2660

Published: Jan. 31, 2023

Bone tissue engineering (BTE) utilizes a special mix of scaffolds, cells, and bioactive factors to regulate the microenvironment bone regeneration form three-dimensional simulation structure regenerate tissue. Silk fibroin (SF) is perhaps most encouraging material for BTE given its tunable mechanical properties, controllable biodegradability, excellent biocompatibility. Numerous studies have confirmed significance SF stimulating formation. In this review, we start by introducing characteristics SF. After that, immunological mechanism osteogenesis summarized, various forms biomaterials latest development prospects in are emphatically introduced. Biomaterials based on great potential engineering, review will serve as resource future design research.

Language: Английский

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Piezoelectric materials for neuroregeneration: a review

Biomaterials Science, Journal Year: 2023, Volume and Issue: 11(22), P. 7296 - 7310

Published: Jan. 1, 2023

The purpose of nerve regeneration via tissue engineering strategies is to create a microenvironment that mimics natural growth for achieving functional recovery. Biomaterial scaffolds offer promising option the clinical treatment large gaps due rapid advancement materials science and regenerative medicine. design biomimetic should take into account inherent properties its environment, such as stiffness, topography, adhesion, conductivity, chemical functionality. Various advanced techniques have been employed develop suitable repair. Since neuronal cells electrical activity, transmission bioelectrical signals crucial recovery nerves. Therefore, an ideal peripheral scaffold activity similar those nerves, in addition delicate structure. Piezoelectric can convert stress changes activate different intracellular signaling pathways critical cell function, which makes them potentially useful regeneration. However, comprehensive review piezoelectric neuroregeneration still lacking. Thus, this systematically summarizes development their application field First, piezoelectricity phenomenon various organisms are briefly introduced. Second, most commonly used neural engineering, including biocompatible polymers, inorganic materials, classified discussed. Finally, challenges future research directions proposed.

Language: Английский

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