Comparative Analysis of Bacterial Cellulose Membranes Synthesized by Chosen Komagataeibacter Strains and Their Application Potential DOI Open Access
Monika Kaczmarek, Marzena Jędrzejczak‐Krzepkowska, Karolina Ludwicka

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(6), P. 3391 - 3391

Published: March 21, 2022

This article presents a comparative analysis of bacterial cellulose membranes synthesized by several strains the Komagataeibacter genus in terms their specific physical, physico-chemical, and mechanical properties. Herein, aim was to choose most suitable microorganisms producing cellulosic materials with greatest potential for fabrication bio-inspired nanocomposites. The selection based on three main steps, starting from evaluation BNC biosynthetic efficiency without addition ethanol, followed assessment breaking strength, physical parameters (compactness, structural integrity, appearance, thickness) obtained biological materials. Ultimately, performed screening procedure, efficiently growing (K. hansenii H3 (6Et), K. rhaeticus K4 (8Et), sp. isolated balsamic vinegar (12Et)) were chosen further modifications, enabling additional functionalization. Here, supplementation growth medium five representative polymeric compounds (citrus/apple pectin, wheat starch, polyvinyl alcohol, polyethylene glycol) led significant changes properties, especially dye loading abilities, water adsorption/retention capacities. resulting nanocomposites can be potentially useful various fields medicine industry, future, they may become practical cost-effective competitor against commercial biomaterials currently available market.

Language: Английский

Bacterial Cellulose and Its Applications DOI Open Access
Soon Mo Choi,

Kummara Madhusudana Rao,

Sun Mi Zo

et al.

Polymers, Journal Year: 2022, Volume and Issue: 14(6), P. 1080 - 1080

Published: March 8, 2022

The sharp increase in the use of cellulose seems to be increasing demand wood; much more research related sustainable or alternative materials is necessary as a lot arable land and natural resources unsustainable. In accordance, attention has focused on bacterial new functional material. It possesses three-dimensional, gelatinous structure consisting with mechanical thermal properties. Moreover, while plant-originated composed cellulose, hemi-cellulose, lignin, attributable composition pure nanofiber mesh spun not elimination other components. due its hydrophilic nature caused by binding water, consequently being hydrogel well biocompatibility, it only used medical fields including artificial skin, cartilage, vessel, wound dressing, but also delivery; some products have even been commercialized. addition, widely various technologies food, paper, textile, electronic electrical applications, considered highly versatile green material tremendous potential. However, many efforts conducted for evolution novel sophisticated environmental affinity, which accompany empowerment enhancement specific this review article, we summarized industry status regarding BC contemplated potential BC.

Language: Английский

Citations

154

Natural polysaccharides: Chemical properties and application in pharmaceutical formulations DOI
Mousumi Tudu, Amalesh Samanta

European Polymer Journal, Journal Year: 2022, Volume and Issue: 184, P. 111801 - 111801

Published: Dec. 30, 2022

Language: Английский

Citations

84

Exopolysaccharides Producing Bacteria: A Review DOI Creative Commons
А. И. Нетрусов, Elena V. Liyaskina,

Irina V. Kurgaeva

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(6), P. 1541 - 1541

Published: June 9, 2023

Bacterial exopolysaccharides (EPS) are essential natural biopolymers used in different areas including biomedicine, food, cosmetic, petroleum, and pharmaceuticals also environmental remediation. The interest them is primarily due to their unique structure properties such as biocompatibility, biodegradability, higher purity, hydrophilic nature, anti-inflammatory, antioxidant, anti-cancer, antibacterial, immune-modulating prebiotic activities. present review summarizes the current research progress on bacterial EPSs properties, biological functions, promising applications various fields of science, industry, medicine, technology, well characteristics isolation sources EPSs-producing strains. This provides an overview latest advances study important industrial xanthan, cellulose, levan. Finally, limitations future directions discussed.

Language: Английский

Citations

62

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential DOI Creative Commons
Mariana Ribeiro, Marco Simões, Carla Vitorino

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(3), P. 188 - 188

Published: March 8, 2024

Hydrogels are polymeric materials that possess a set of characteristics meeting various requirements an ideal wound dressing, making them promising for care. These features include, among others, the ability to absorb and retain large amounts water capacity closely mimic native structures, such as extracellular matrix, facilitating cellular processes like proliferation differentiation. The polymers used in hydrogel formulations exhibit broad spectrum properties, allowing be classified into two main categories: natural collagen chitosan, synthetic polyurethane polyethylene glycol. This review offers comprehensive overview critical analysis key can constitute hydrogels, beginning with brief contextualization polymers. It delves their function, origin, chemical structure, highlighting sources extraction obtaining. Additionally, this encompasses intrinsic properties these roles healing process, accompanied, whenever available, by explanations underlying mechanisms action. also addresses limitations describes some studies on effectiveness isolated promoting skin regeneration healing. Subsequently, we briefly discuss application strategies hydrogels derived from potential promote process. achieved due role stimulation angiogenesis, example, or through incorporation substances growth factors drugs, antimicrobials, imparting new hydrogels. In addition substance incorporation, is related serve three-dimensional matrix cell culture, whether it involves loading cells recruiting site, where they proliferate scaffold form tissue. latter strategy presupposes biosensors real-time monitoring conditions, temperature pH. Future prospects then ultimately addressed. As far aware, manuscript represents first approach brings together critically analyzes fundamental aspects both constituting context cutaneous will foundational point future studies, aiming contribute development effective environmentally friendly dressing wounds.

Language: Английский

Citations

32

Recent advances in protein-polysaccharide based biocomposites and their potential applications in food packaging: A review DOI

Perumal Thivya,

P. Gururaj,

Nalla Bhanu Prakash Reddy

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131757 - 131757

Published: April 22, 2024

Language: Английский

Citations

20

The orchestration of sustained drug delivery by bacterial cellulose/gelatin nanocomposites reinforced with carboxylic carbon nanotubes DOI
Bahareh Behrouznejad,

Sayedeh Boshra Sadat,

Elahe Masaeli

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 333, P. 121917 - 121917

Published: Feb. 9, 2024

Language: Английский

Citations

17

Cellulose Based Nano-Scaffolds for Targeted Cancer Therapies: Current Status and Future Perspective DOI Creative Commons
Yanwei Li, Wei Liu, Yuanyuan Wang

et al.

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 199 - 213

Published: Jan. 1, 2025

Abstract: In the last few years, cellulose has garnered much interest for its application in drug delivery, especially cancer therapy. It special properties like biocompatibility, biodegradability, high porosity, and water permeability render it a good candidate developing efficient carriers anticancer agents. Cellulose based nanomaterials nanofibers, bacterial cellulose, nanocrystals microcrystalline as delivery vehicles targeted to cells are reviewed. This review elaborates on synthesis, functionalization, strategies of these nanocarriers, shows how they facilitate improve stability, bioavailability tumor sites. Their possibilities tool overcome limitations conventional therapeutics also discussed. We explore future directions improving efficacy Keywords: – scaffold, therapy, biomedical applications

Language: Английский

Citations

3

Bacterial Cellulose as a Versatile Biomaterial for Wound Dressing Application DOI Creative Commons
Júlia Didier Pedrosa de Amorim, Cláudio José Galdino da Silva,

Alexandre D’Lamare Maia de Medeiros

et al.

Molecules, Journal Year: 2022, Volume and Issue: 27(17), P. 5580 - 5580

Published: Aug. 30, 2022

Chronic ulcers are among the main causes of morbidity and mortality due to high probability infection sepsis therefore exert a significant impact on public health resources. Numerous types dressings used for treatment skin ulcers-each with different advantages disadvantages. Bacterial cellulose (BC) has received enormous interest in cosmetic, pharmaceutical, medical fields its biological, physical, mechanical characteristics, which enable creation polymer composites blends broad applications. In field, BC was at first wound dressings, tissue regeneration, artificial blood vessels. This material is suitable treating various diseases considerable fluid retention medication loading properties. membranes as temporary dressing treatments their excellent fit body, reduction pain, acceleration epithelial regeneration. BC-based have been evaluated synthesized both vitro vivo create an ideal microenvironment healing. review describes methods producing handling use field highlights qualities detail emphasis biomedical reports that demonstrate utility. Moreover, it gives account applications, especially engineering materials reported until date. also includes patents applied material.

Language: Английский

Citations

66

Bacterial Cellulose-Based Polymer Nanocomposites: A Review DOI Open Access
В. В. Ревин, Elena V. Liyaskina, Marina V. Parchaykina

et al.

Polymers, Journal Year: 2022, Volume and Issue: 14(21), P. 4670 - 4670

Published: Nov. 2, 2022

Bacterial cellulose (BC) is currently one of the most popular environmentally friendly materials with unique structural and physicochemical properties for obtaining various functional a wide range applications. In this regard, literature reporting on bacterial nanocellulose has increased exponentially in past decade. Currently, extensive investigations aim at promoting manufacturing BC-based nanocomposites other components such as nanoparticles, polymers, biomolecules, that will enable to develop advanced novel functionalities. However, commercial production limited by high cost low yield BC, lack highly efficient industrial technologies well. Therefore, present review aimed studying current data field BC purpose its further usage obtain polymer nanocomposites. The highlights progress synthesizing their applications biomedical fields, wound healing, drug delivery, tissue engineering. nanocellulose-based biosensors adsorbents were introduced herein.

Language: Английский

Citations

42

A role of biomaterials in tissue engineering and drug encapsulation DOI
Reeya Agrawal, Sangeeta Singh, Kuldeep K. Saxena

et al.

Proceedings of the Institution of Mechanical Engineers Part E Journal of Process Mechanical Engineering, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 19, 2023

The paper provides an introduction to biomaterials covered and their available types, such as metal, ceramic, polymer, composites. Biomaterials are structures, devices, or materials that may repair implant tissue. biocompatible have high mechanical strength, need a long time break down. A biomaterial is any natural synthetic material regularly touches the human body utilized replace restore biological tissue—metallic systems in numerous ceramic polymeric systems. Polymers had significant impact on medical technology development. Furthermore, features of mechanical, physical, chemical qualities been detailed assist users selecting best for needs based these properties. While do not tissues’ function, they good physical allow them be used tissue substitutes. Apart from this, applied various fields, including medicine pharmacy. Biodegradable biomaterials, particular, offer advantage being able broken down removed once purpose completed. most common engineering, delivery systems, orthopedic, orthodontic, wound healing, cardiovascular applications. conclusion summarizes advantageous science. Biomaterial cellular biology researchers working make biomanufacturing technologies more broadly time. main area focus medicine, where critical studying preventing uncommon diseases.

Language: Английский

Citations

32