Silk fibroin-based scaffolds for wound healing applications with metal oxide nanoparticles

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105689 - 105689

Published: April 21, 2024

In the last few years, wound healing and development of "ideal" biomaterials that provide quick recovery minimize scarring have represented one most important priorities researchers. this direction, silk fibroin (SF) scaffolds gained substantial awareness, as a promising polymer owing to their increased biocompatibility, outstanding mechanical properties, biodegradability, especially tensile strength. Furthermore, SF is acknowledged accelerate process by encouraging cell growth proliferation, also migration different types cells are included in stages process. Therefore, metal oxide nanoparticles (NPs), such iron (FeO), copper (CuO), zinc (ZnO), or magnesium (MgO) NPs, been extensively researched for antimicrobial properties ability enhance tissue regeneration addition SF. When introduced within scaffolds, these NPs impart enhanced including improved scaffold stability durability. Moreover, presence could increase biocompatibility facilitating adhesion, migration, ultimately promoting processes. The incorporation other natural polymers into has thus emerged favorable method therapeutic potential developed biomaterial. This review aims an overview advancements containing applications.

Language: Английский

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Switchable biomaterials for wastewater treatment: From material innovations to technological advancements

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160928 - 160928

Published: Feb. 1, 2025

Language: Английский

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Silk fibroin-derived electrospun materials for biomedical applications: A review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 254, P. 127641 - 127641

Published: Oct. 31, 2023

Language: Английский

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Therapeutic functions of medical implants from various material categories with integrated biomacromolecular systems

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 10, 2025

Medical implants are designed to replace missing parts or improve body functions and must be capable of providing structural support therapeutic intervention for a medical condition. Advances in materials science have enabled the development devices made from metals, polymers, bioceramics, composites, each with its specific advantages limitations. This review analyzes incorporation biopolymers, proteins, other biomacromolecules into implants, focusing on their role biological integration functions. It synthesizes advancements surface modification, discusses as carriers controlled drug release, explores application nanoceramics composites osseointegration tissue regeneration. Biomacromolecule systems interacting device components agents - such growth factors (GFs), antibiotics, allowing control over substance release. Incorporating these enables localized treatments regeneration, osseointegration, post-surgery infection control, disease pre-existing conditions. The highlights materials' customization opportunities, by covering mechanical perspectives. Developing hybrid delivery align recent efforts interdisciplinary personalized medicine implant innovations. For instance, trend was observed integrating inorganic (especially nanoceramics, e.g., hydroxyapatite) organic phases better interaction tissues faster recovery. article supports understanding how can create more personalized, functional, durable, biocompatible devices.

Language: Английский

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Review on titanium oxide (TiO2) nanomaterials in multidomain investigations

Nano-Structures & Nano-Objects, Journal Year: 2025, Volume and Issue: 41, P. 101455 - 101455

Published: Feb. 1, 2025

Language: Английский

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Antimicrobial hybrid coatings: A review on applications of nano ZnO based materials for biomedical applications

Biomaterials Advances, Journal Year: 2025, Volume and Issue: 172, P. 214246 - 214246

Published: Feb. 27, 2025

Language: Английский

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Antibacterial Ceramics for Dental Applications

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(8), P. 4553 - 4553

Published: April 21, 2025

Background: The aim of this review was to evaluate the antibacterial properties functionalized bioceramics for dental applications. Methods: electronic databases PubMed, Medline, ProQuest, and Google Scholar were used search peer-reviewed scientific publications published between 2020 2025 that provide insights answer research questions related role antibacterial-functionalized in combating pathogens dentistry without triggering immune reactions inflammation, as well on their efficacy against various whether understanding mechanism can promote development glass-ceramic bioceramic with long-term activity. keywords were: bioglass, bioceramic, biocompatible, antibacterial, osseointegration, implant, bioactive materials. Results: Bacterial infections play a key longevity medical devices. A crucial problem is drug-resistant bacteria. Antibacterial ceramics have received great attention recently because activity, good mechanical properties, biocompatibility, bioactivity. This provides detailed examination complex interactions bacteria, cells, from clinical perspective. focus researchers developing new-generation multifunctionality, particular are independent conventional antibiotics. highlight exploration dual functions such promoting bone regeneration which potential revolutionize implant technology. Another modifying surface hydrophilic hydrophobic order increase activity bioceramics. Conclusions: help understand current state-of-the-art activities bioceramics, could application.

Language: Английский

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Applications and interventions of polymers and nanomaterials in alveolar bone regeneration and tooth dentistry

RSC Advances, Journal Year: 2024, Volume and Issue: 14(49), P. 36226 - 36245

Published: Jan. 1, 2024

Inflammatory diseases exert a significant influence on the periodontium, serving as primary contributor to development of periodontitis and alveolar bone loss.

Language: Английский

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Y-Branched Titanium Dioxide Nanotubes as a Potential Antimicrobial Coating for Implants

Crystals, Journal Year: 2023, Volume and Issue: 13(12), P. 1695 - 1695

Published: Dec. 17, 2023

The early loss of dental implants can be avoided with systemic antibiotics, however there are potentially significant side effects. Consequently, the use local drug administration techniques is necessary to make implant therapy more practical. In this study, Y-branched nanotubes were prepared by non-expensive and simple anodization in two steps. Tests performed highlight their potential for antibiotic administration. able incorporate a dose Tetracycline ensure its electrochemical stability. presence tetracycline significantly enhanced antibacterial efficacy, resulting an increase up 55% Escherichia coli Pseudomonas aeruginosa 50% Staphylococcus aureus. comparable effects nanostructured surfaces promoting antimicrobial action. Moreover, addition does not influence structural, morphological stability properties deposited TiO2 films.

Language: Английский

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Reduced TiO₂ Nanotubes/Silk Fibroin/ZnO as a Promising Hybrid Antibacterial Coating

ChemPlusChem, Journal Year: 2023, Volume and Issue: 89(3)

Published: Oct. 27, 2023

The current research aims to elucidate the influence of reduction process TiO

Language: Английский

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