Polymers,
Journal Year:
2024,
Volume and Issue:
16(24), P. 3584 - 3584
Published: Dec. 21, 2024
Photocurable
materials
offer
a
rapid
transition
from
liquid
to
solid
state,
and
have
recently
received
great
interest
in
the
medical
field.
However,
while
dental
resins
are
very
popular,
only
few
been
developed
for
soft
tissue
repair.
This
study
aims
synthesize
difunctional
methacrylate
monomer
using
dibutyltin
dilaurate
which
is
suitable
photocuring
of
materials.
These
were
compared
with
PhotoBioCure®
(Szczecin,
Poland)
material
similar
molecular
weight,
Mn
~7000
g/mol
on
average.
Infrared
spectroscopy
was
used
monitor
two-step
synthesis
catalyzed
dilaurate,
spectroscopic
chromatographic
methods
determine
chemical
structure
weight
monomers.
Photopolymerization
kinetics
under
varying
light
intensities
explored
nitrogen
atmosphere
representative
The
mechanical
testing
resulting
elastomeric
films
confirmed
tensile
strength
modulus
values
consistent
parameters
range
3–4
MPa.
3D
printability
macromonomers
also
assessed.
Additionally,
cytotoxicity
assessments
cultured
cells
showed
high
cell
viability
(97%)
all
new
Overall,
we
demonstrate
that
monomers
converted
flexible
solids
during
photopolymerization
show
potential
biomedical
applications.
ACS Biomaterials Science & Engineering,
Journal Year:
2024,
Volume and Issue:
10(5), P. 2616 - 2635
Published: April 26, 2024
Primary
brain
tumor
is
one
of
the
most
fatal
diseases.
The
malignant
type
among
them,
glioblastoma
(GBM),
has
low
survival
rates.
Standard
treatments
reduce
life
quality
patients
due
to
serious
side
effects.
Tumor
aggressiveness
and
unique
structure
render
removal
tumors
development
new
therapies
challenging.
To
elucidate
characteristics
examine
their
response
drugs,
realistic
systems
that
mimic
environment
cellular
crosstalk
are
desperately
needed.
In
past
decade,
3D
GBM
models
have
been
presented
as
excellent
platforms
they
allowed
investigation
phenotypes
testing
innovative
therapeutic
strategies.
scope,
bioprinting
technology
offers
utilities
such
fabricating
bioprinted
structures
in
a
layer-by-layer
manner
precisely
controlled
deposition
materials
cells,
can
be
integrated
with
other
technologies
like
microfluidics
approach.
This
Review
covers
studies
investigated
models,
especially
using
techniques
essential
parameters
affect
result
study
frequently
used
physical
hydrogel,
conditions,
cross-linking
methods,
characterization
techniques.
Small Science,
Journal Year:
2024,
Volume and Issue:
4(8)
Published: May 23, 2024
Light‐assisted
3D
printing
technology,
which
uses
a
light
source
to
solidify
photopolymerizable
prepolymer
solution,
has
shown
great
potential
in
the
development
of
antibacterial
hydrogels
with
high‐resolution,
specific
features
and
functionalities.
3D‐printed
customized
structures
functions
are
widely
used
tissue
engineering,
regenerative
medicine,
wound
healing,
implants
advance
modeling
treatment
diseases.
In
current
review,
an
overview
light‐assisted
technologies
is
first
provided
for
hydrogels.
Novel
strategies
involving
integration
inorganic
nanomaterials,
antibiotics,
functional
polymers
into
enhancement
effects
then
discussed.
Finally,
perspective
advanced
design
using
artificial
intelligence
machine
learning
proposed,
providing
comprehensive
yet
succinct
examination
purposes.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: March 13, 2024
Bio-printed
hydrogels
have
evolved
as
one
of
the
best
regenerative
medicine
and
tissue
engineering
platforms
due
to
their
outstanding
cell-friendly
microenvironment.
A
correct
hydrogel
ink
formulation
is
critical
for
creating
desired
scaffolds
that
better
fidelity
after
printing.
Gelatin
its
derivatives
sparked
intense
interest
in
various
biomedical
sectors
because
biocompatibility,
biodegradability,
ease
functionalization,
rapid
gelling
tendency.
As
a
result,
this
report
emphasizes
relevance
gelatin-based
fabricating
bio-printed
orthopedic
applications.
Starting
with
what
bio-printing
are
all
about.
We
further
summarized
different
techniques
explored
applications,
including
few
recent
studies.
also
discussed
suitability
gelatin
biopolymer
both
3D
4D
printing
materials.
extrusion
most
widely
used
gelatin-based,
we
summarize
rheological
features
bio-ink.
Lastly,
elaborate
on
studies
orthopedics
potential
clinical
translation
issues,
research
possibilities.
Advances in Wound Care,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 5, 2025
Significance:
The
skin
serves
as
the
primary
defense
against
external
stimuli,
making
it
vulnerable
to
damage.
Injuries
can
cause
a
dysregulated
environment,
resulting
in
chronic
inflammation
and
inhibition
of
cell
proliferation
migration,
which
delays
recovery.
Innovative
approaches,
such
three-dimensional
(3D)
bioprinting,
foster
controlled
healing
environment
by
promoting
synergy
between
microbiome
cells.
Recent
Advances:
Traditional
approaches
wound
have
focused
on
fostering
an
conducive
interplay
cells,
extracellular
proteins,
growth
factors.
3D
manufacturing
technology
with
applications
tissue
engineering,
deposits
biomaterial-based
bioink
containing
living
cells
fabricate
custom-designed
scaffolds
layer-by-layer
fashion.
This
process
controls
architecture
composition
construct,
producing
multilayered
complex
structures
skin.
Critical
Issues:
selection
biomaterials
for
has
been
challenge
when
engineering.
While
prioritizing
mechanical
properties,
current
often
lack
ability
interact
environmental
stimuli
pH,
temperature,
or
oxygen
levels.
Employing
smart
that
integrate
bioactive
molecules
adapt
conditions
could
overcome
these
limitations.
innovation
would
enable
create
sustainable
wound-healing
balance,
reducing
inflammation,
facilitating
cellular
recovery
restoration,
addressing
critical
gaps
existing
care
solutions.
Future
Directions:
Novel
formulations
injury
are
improving
long-term
viability,
proliferation,
vascularization,
immune
integration.
Efficient
using
potential
microenriched
environments
support
restore
regulation.
promising
direction
future
research
aims
improve
patient
outcomes
care.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
13
Published: April 14, 2025
Bile
duct
disorders,
including
cholangiocarcinoma,
primary
sclerosing
cholangitis,
and
iatrogenic
injuries,
pose
significant
clinical
challenges
due
to
limited
regenerative
capacity
the
complexity
of
biliary
tree.
In
recent
years,
3D
bioprinting
has
emerged
as
a
promising
approach
for
bile
tissue
engineering
by
providing
patient-specific
geometries
facilitating
spatial
organization
cells,
scaffolding
materials,
bioactive
factors.
This
review
presents
comprehensive
overview
techniques
engineering,
focusing
on
fundamental
principles,
biomaterial
selection,
current
achievements,
key
challenges,
future
perspectives.
We
systematically
discuss
latest
technological
breakthroughs,
highlight
emerging
innovations
such
organoid-based
strategies
microfluidic-assisted
printing,
evaluate
prospects
translation.
Finally,
we
outline
main
challenges—such
biocompatibility
vascularization,
immunological
barriers,
standardization
protocols,
regulatory
hurdles—and
propose
directions
research,
emphasizing
multidisciplinary
collaboration
translational
studies.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(9), P. 1287 - 1287
Published: May 7, 2025
Digital
light
processing
(DLP)
technology
stands
out
as
a
groundbreaking
method
in
the
field
of
biomedical
engineering
that
enables
production
highly
precise
structures
using
photopolymerizable
materials.
Smart
materials
such
shape
memory
polymers,
hydrogels,
and
nanocomposites
are
used
ideal
for
personalized
medicine
applications
thanks
to
their
properties
superior
mechanical
strength,
biocompatibility,
sensitivity
environmental
stimuli
DLP
technology.
The
integration
these
with
functional
complex
structures,
especially
areas
bone
soft
tissue
engineering,
drug
delivery,
biosensor
production.
However,
limited
material
diversity,
scalability
problems
processes,
technical
difficulties
optimizing
bioprinting
parameters
among
main
obstacles
this
field.
This
study
systematically
examines
role
smart
biomaterials
DLP-based
processes.
It
addresses
innovative
regenerative
medicine.
also
comprehensively
evaluates
its
contributions
discusses
future
research
overcome
current
limitations.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(5), P. 166 - 166
Published: May 8, 2025
The
rapid
development
of
microfluidics
has
driven
innovations
in
material
engineering,
particularly
through
its
ability
to
precisely
manipulate
fluids
and
cells
at
microscopic
scales.
Microfluidic
biomaterials,
a
cutting-edge
interdisciplinary
field
integrating
microfluidic
technology
with
biomaterials
science,
are
revolutionizing
biomedical
research.
This
review
focuses
on
the
functional
design
fabrication
organ-on-a-chip
(OoAC)
platforms
via
3D
bioprinting,
explores
applications
drug
delivery,
cell
culture,
tissue
evaluates
potential
systems
advancing
personalized
healthcare.
We
systematically
analyze
evolution
materials—from
silicon
glass
polymers
paper—and
highlight
advantages
bioprinting
over
traditional
methods.
Currently,
despite
significant
advances
medicine,
challenges
scalability,
stability,
clinical
translation
remain.
future
will
depend
combining
dynamic
design,
developing
hybrid
strategies
that
combine
molds
bio-printed
structures,
using
artificial
intelligence
monitor
delivery
or
response
real
time.
believe
collaborations
between
materials
micromachining,
medicine
accelerate
into
therapies
high-throughput
screening
tools.
