Biosynthesis of Palladium Nanoparticles by Using Aqueous Bark Extract of Quercus dalechampii, Q. frainetto, and Q. petraea for Potential Antioxidant and Antimicrobial Applications DOI Creative Commons

Năstaca-Alina Coman,

Mihai Babotă, Alexandru Nicolescu

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(23), P. 3390 - 3390

Published: Dec. 3, 2024

This study aimed to synthesize palladium nanoparticles (PdNPs) using bioactive compounds from aqueous extracts of

Language: Английский

Novel silver nanoparticle-based biomaterials for combating Klebsiella pneumoniae biofilms DOI Creative Commons

Eslam Elashkar,

Rihaf Alfaraj, Ola M. El‐Borady

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 9, 2025

Klebsiella pneumoniae is a significant nosocomial pathogen that has developed resistance to multiple antibiotics, often forming biofilms enhance its virulence. This study investigated the efficacy of novel nanoformulation, AgNPs@chitosan-NaF, in combating K. biofilms. Antimicrobial susceptibility testing was performed assess antibiotic profile isolates. The antibiofilm activity AgNPs@chitosan-NaF evaluated using crystal violet staining and scanning electron microscopy. underlying mechanisms action were through gene expression analysis. majority isolates exhibited high levels multidrug resistance. demonstrated superior biofilm inhibition compared AgNPs@chitosan, significantly reducing biomass disrupting architecture at MICs ranging from 0.125 1 μg/mL. Mechanistic studies revealed nanoformulation downregulated key biofilm-associated genes, including treC, fimA, mrkA, ecpA. While concentration-dependent cytotoxic effect on both normal cancer cell lines, minimal cytotoxicity observed concentrations below 31.25 highlights synergistic silver nanoparticles, chitosan, sodium fluoride emerges as promising therapeutic strategy address challenge multidrug-resistant bacterial infections.

Language: Английский

Citations

2
A Review of Chitosan-Based Materials for Biomedical, Food, and Water Treatment Applications DOI Open Access
Dan Chicea, Alexandra Nicolae-Maranciuc

Materials, Journal Year: 2024, Volume and Issue: 17(23), P. 5770 - 5770

Published: Nov. 25, 2024

Chitosan, a natural biopolymer with excellent biocompatibility, biodegradability, and modifiable structure, has broad applications in regenerative medicine, tissue engineering, food packaging, environmental technology. Its abundance, solubility acidic solutions, capacity for chemical modification make it highly adaptable creating specialized derivatives enhanced properties. Recent advances have demonstrated chitosan's efficacy composite systems regeneration, drug delivery, antimicrobial applications. This review examines unique properties, focus on its antibacterial activity as influenced by factors like pH, concentration, molecular weight, deacetylation degree. Additionally, potential sustainable, non-toxic material eco-friendly packaging water treatment is explored, highlighting the growing interest chitosan composites other polymers metallic nanoparticles biomedical

Language: Английский

Citations

5
5H Pyrolo(3,4-b)Pyrazin-5,7-(6H)-dione 6-(N-Chitosanimide nanoparticle) composite nano silver and encapsulation in γ-cyclodextrin: Synthesis, molecular docking, and biological evaluation for thyroid cancer treatment DOI

Entesar A. Hassan,

A. S. Abdelnaser,

Samar Ibrahem

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140859 - 140859

Published: Feb. 1, 2025

Language: Английский

Citations

0
Green Synthesis of Metallic Nanoparticles from Quercus Bark Extracts: Characterization and Functional Properties DOI Creative Commons

Năstaca-Alina Coman,

Alexandra Nicolae-Maranciuc, Lavinia Berța

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(7), P. 822 - 822

Published: July 9, 2024

species are utilized for their durable wood, providing sustenance wildlife, conserving biodiversity, and contributing ecological, medicinal, esthetic benefits to ecosystems landscapes. In this study, we aimed use the bark of three

Language: Английский

Citations

2
Advances in nephroprotection: the therapeutic role of selenium, silver, and gold nanoparticles in renal health DOI

Karthik K Karunakar,

Elizabeth Rani Edwin,

Meenaloshini Gopalakrishnan

et al.

International Urology and Nephrology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 23, 2024

Language: Английский

Citations

2
Stable PEG-Silver Nanoparticles Biomaterial for Medical Applications DOI
Alexandra Nicolae-Maranciuc, Dan Chicea

Published: Sept. 8, 2024

Language: Английский

Citations

0
Biosynthesis of Palladium Nanoparticles by Using Aqueous Bark Extract of Quercus dalechampii, Q. frainetto, and Q. petraea for Potential Antioxidant and Antimicrobial Applications DOI Creative Commons

Năstaca-Alina Coman,

Mihai Babotă, Alexandru Nicolescu

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(23), P. 3390 - 3390

Published: Dec. 3, 2024

This study aimed to synthesize palladium nanoparticles (PdNPs) using bioactive compounds from aqueous extracts of

Language: Английский

Citations

0