Advancing Cancer Therapy with Quantum Dots and Other Nanostructures: A Review of Drug Delivery Innovations, Applications, and Challenges

Cancers, Journal Year: 2025, Volume and Issue: 17(5), P. 878 - 878

Published: March 4, 2025

Nanotechnology, particularly quantum dots (QDs), has ushered in a transformative era the pharmaceutical and medical industries, offering notable opportunities for nanoscale advancements. These particles, known their exceptional optical properties confinement, have emerged as indispensable tools cancer drug delivery bioimaging. This review delves into various conjugation techniques with QDs, including covalent linking, non-covalent conjugation, click chemistry, disulfide linkage, pH-sensitive linkage. Each method provides distinct advantages, such enhanced stability, reversibility, specificity, controlled release. Moreover, QDs demonstrated significant promise oncology by efficiently delivering drugs to cancerous tissues while minimising systemic toxicity. Investigations applications different cancers, blood, brain, cervical, breast etc., reveal efficacy targeted delivery, real-time imaging, improved therapeutic outcomes. However, challenges potential toxicity, pharmacokinetics, targeting specificity must be addressed fully harness benefits of therapy. Future research should focus on developing biocompatible optimising techniques, elucidating safety profiles long-term effects biological systems. Overall, represent promising frontier treatment, multifaceted capabilities that hold outcomes reduced side across cancers.

Language: Английский

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Exosomes derived from natural killer cells: transforming immunotherapy for aggressive breast cancer

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(4)

Published: March 18, 2025

Language: Английский

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Emergence of Quantum Dots as Innovative Tools for Early Diagnosis and Advanced Treatment of Breast Cancer

ChemMedChem, Journal Year: 2024, Volume and Issue: 19(16)

Published: May 10, 2024

Quantum dots (QDs) semiconducting nanomaterials, have garnered attention due to their distinctive properties, including small size, high luminescence, and biocompatibility. In the context of triple-negative breast cancer (TNBC), notorious for its resistance conventional treatments, QDs exhibit promising potential enhancing diagnostic imaging providing targeted therapies. This review underscores recent advancements in utilization techniques, such as fluorescence tomography magnetic resonance imaging, aiming at early precise detection tumors. Emphasis is placed on significance QD design, synthesis functionalization processes well use innovative strategies drug delivery, capitalizing ability selectively deliver therapeutic agents cells. As research this field advances rapidly, covers a classification according composition, characterization techniques than can be used determine properties and, subsequently, emphasizes findings TNBC-targeting, highlighting imperative need address challenges, like toxicity or methodologies standardization. Collectively, explored thus far suggest that could pave way diagnosis effective therapy TNBC, representing significant stride toward personalized treating TNBC.

Language: Английский

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Tannic acid cross-linked polyethylenimine quantum dot nanoclusters for efficient DNA release

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143055 - 143055

Published: April 1, 2025

Language: Английский

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Nanotechnology-based drug delivery for breast cancer treatment: Current applications and future directions

European Journal of Medicinal Chemistry Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100268 - 100268

Published: April 1, 2025

Language: Английский

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Recent Trends in Drug Delivery Systems

Assay and Drug Development Technologies, Journal Year: 2025, Volume and Issue: unknown

Published: May 7, 2025

Drug delivery systems are now being advanced by integrating sophisticated nanotechnologies to enhance therapeutic efficacy. Tremendous advancement has been achieved in the field of cancer therapy through utilization hyaluronic acid-based nanocarriers, which well-acknowledged for their capacity transport medication precisely targeted regions. Quantum dots exhibit unique optical properties that allow precise drug administration and monitoring capabilities. Carbon nanotubes provide a large surface area exceptional strength, allowing manipulation patterns. Dendrimers versatile structures can many drugs simultaneously, whereas mesoporous silica-functionalized nanoparticles exact release rate pharmaceuticals. Polymer-lipid hybrid synergistically integrate durability polymers with compatibility lipids, hence augmenting availability within body. Hexagonal boron nitride nanosheets becoming more recognized as favorable carriers due biocompatibility potential tailored administration. These achievements demonstrate changes happening pharmaceutical administration, where nanotechnology is used tackle issues such restricted bioavailability unanticipated adverse effects. This ultimately enhances effectiveness medicines improves patient outcomes. Future investigations will focus on improving these technologies broader applications.

Language: Английский

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Transforming oncology with carbon quantum dots: Synthesis, properties, and therapeutic potential

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 7, P. 100181 - 100181

Published: Jan. 1, 2025

Language: Английский

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The antioxidant and selective apoptotic activities of modified auraptene-loaded graphene quantum dot nanoparticles (M-AGQD-NP)

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: Sept. 27, 2024

Language: Английский

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