THE ROLE OF BIOCERAMICS IN MODERN DENTISTRY: FROM EARLY INNOVATIONS TO FUTURE DIRECTIONS DOI Creative Commons

Diana Hanu,

Sorina Mihaela Solomon,

Sorina Paduraru

et al.

Published: Sept. 15, 2024

The use of bioceramics in modern dentistry has significantly evolved, offering enhanced clinical outcomes various procedures. This article reviews the development and application bioceramic materials, focusing on their biocompatibility, ability to stimulate tissue regeneration, chemical stability. Notable materials such as Mineral Trioxide Aggregate (MTA) Biodentine are highlighted for role endodontic treatments bone regeneration. paper also discusses innovations synthesis functionalization bioceramics, including doping with elements integration nanotechnology, which have led advancements faster setting times improved antimicrobial properties. Furthermore, provides a historical perspective transition from early bioactive like hydroxyapatite, emphasizing impact implantology future directions potential regenerative medicine activity, explored.

Language: Английский

The critical role of nano-hydroxyapatites as an advanced scaffold in drug delivery towards efficient bone regeneration: Recent progress and challenges DOI Creative Commons

Amir Hatami kaleshtari,

Samira Farjaminejad,

Melika Hasani

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100692 - 100692

Published: Jan. 1, 2025

Language: Английский

Citations

2
Therapeutic functions of medical implants from various material categories with integrated biomacromolecular systems DOI Creative Commons
Guilherme Bedeschi Calais,

Guillermina Garcia,

Celso Fidelis de Moura Júnior

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 10, 2025

Medical implants are designed to replace missing parts or improve body functions and must be capable of providing structural support therapeutic intervention for a medical condition. Advances in materials science have enabled the development devices made from metals, polymers, bioceramics, composites, each with its specific advantages limitations. This review analyzes incorporation biopolymers, proteins, other biomacromolecules into implants, focusing on their role biological integration functions. It synthesizes advancements surface modification, discusses as carriers controlled drug release, explores application nanoceramics composites osseointegration tissue regeneration. Biomacromolecule systems interacting device components agents - such growth factors (GFs), antibiotics, allowing control over substance release. Incorporating these enables localized treatments regeneration, osseointegration, post-surgery infection control, disease pre-existing conditions. The highlights materials' customization opportunities, by covering mechanical perspectives. Developing hybrid delivery align recent efforts interdisciplinary personalized medicine implant innovations. For instance, trend was observed integrating inorganic (especially nanoceramics, e.g., hydroxyapatite) organic phases better interaction tissues faster recovery. article supports understanding how can create more personalized, functional, durable, biocompatible devices.

Language: Английский

Citations

0
Multifunctional electrospinning periosteum: Development status and prospect DOI

Jinli Zhu,

Meifeng Li,

Shuoshuo Yang

et al.

Journal of Biomaterials Applications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 11, 2025

In the repair of large bone defects, loss periosteum can result in diminished osteoinductive activity, nonunion, and incomplete regeneration structure, ultimately compromising efficiency regeneration. Therefore, research development tissue-engineered which replace function has become focus current research. The functionalized electrospinning is expected to mimic natural enhance processes more effectively. This review explores construction strategies for electrospun from following perspectives: ⅰ) bioactive factor modification (bone morphogenetic protein-2 (BMP-2), vascular endothelial growth (VEGF) etc.), ⅱ) inorganic compound modification, ⅲ) drug ⅳ) artificial response physical stimuli. Furthermore, through electrospinning, conjunction with other strategies, also analyzed. Finally, challenges prospects are discussed.

Language: Английский

Citations

0
Application of Hydroxyapatite Composites in Bone Tissue Engineering: A Review DOI Creative Commons

Weijie Liu,

N.G. Yen Cheong,

Zheyu He

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(4), P. 127 - 127

Published: April 2, 2025

The treatment of bone defects is complicated by clinical conditions, such as trauma, tumor resection, and infection, which result in impair the bone’s regenerative capacity. Hydroxyapatite (HAp), primary inorganic component bone, possesses good biocompatibility osteoconductivity. However, it has poor mechanical properties, a slow degradation rate, limited functionality, necessitating combination with other materials to broaden its application scope. This paper summarizes importance properties HAp composites provides categorized review current research on tissue engineering. These composite scaffolds not only offer excellent support for cell growth regeneration but also facilitate new formation vascularization. Additionally, challenges faced composites, material property optimization improvement preparation techniques, are discussed. applications defect repair, dental implants, spinal fusion, fields.

Language: Английский

Citations

0
Hydroxyapatite microspheres encapsulated within hybrid hydrogel promote skin regeneration through the activation of Calcium Signaling and Motor Protein pathway DOI
Shuo Liu, Song Lu,

Shuwen Huang

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 287 - 304

Published: April 14, 2025

Language: Английский

Citations

0
Synthesis and Characterization of Dicalcium Phosphate Dihydrate from Marine Mollusks (Conasprella bermudensis and Oliva Sayana) DOI Creative Commons
Md Abu Kawsar, Md. Sahadat Hossain,

Tasnimul Quader Tazim

et al.

Results in Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 100564 - 100564

Published: May 1, 2025

Language: Английский

Citations

0
A Critical Review of Natural and Synthetic Polymer-Based Biological Apatite Composites for Bone Tissue Engineering DOI Open Access
Wasan Alkaron, Alaa Almansoori, Csaba Balázsi

et al.

Journal of Composites Science, Journal Year: 2024, Volume and Issue: 8(12), P. 523 - 523

Published: Dec. 12, 2024

During the past decade, there has been a continued increase in demand for bone defect repair and replacement resulting from long-term illnesses or traumatic incidents. To address these challenges, tissue engineering research focused on biomedical applications. This field concentrated development of suitable materials to enhance biological functionality integration. Toward this aim, it is necessary develop proper material that provides good osseointegration mechanical behavior by combining biopolymers with ceramics, which their stability mineralization process. Hydroxyapatite (HAp) synthesized natural resources owing its unique properties; example, can mimic composition bones teeth humans animals. Biopolymers, including chitosan alginate, combined HAp, offer chemical strength required engineering. Composite biomaterials containing hydroxyapatite could be potential substitute artificial synthetic grafts. Utilizing various polymers fabrication methodologies would efficiently customize physicochemical properties synergy biodegradation, thus enhancing regeneration. review summarizes commonly used engineering, emphasizing advantages limitations. paper also highlights recent advances production investigation HAp-based polymer composites

Language: Английский

Citations

2
THE ROLE OF BIOCERAMICS IN MODERN DENTISTRY: FROM EARLY INNOVATIONS TO FUTURE DIRECTIONS DOI Creative Commons

Diana Hanu,

Sorina Mihaela Solomon,

Sorina Paduraru

et al.

Published: Sept. 15, 2024

The use of bioceramics in modern dentistry has significantly evolved, offering enhanced clinical outcomes various procedures. This article reviews the development and application bioceramic materials, focusing on their biocompatibility, ability to stimulate tissue regeneration, chemical stability. Notable materials such as Mineral Trioxide Aggregate (MTA) Biodentine are highlighted for role endodontic treatments bone regeneration. paper also discusses innovations synthesis functionalization bioceramics, including doping with elements integration nanotechnology, which have led advancements faster setting times improved antimicrobial properties. Furthermore, provides a historical perspective transition from early bioactive like hydroxyapatite, emphasizing impact implantology future directions potential regenerative medicine activity, explored.

Language: Английский

Citations

0