miRNAs and their multifaceted role in cutaneous wound healing
Reda Mansour,
No information about this author
Sherif S. Abdel Mageed,
No information about this author
Farah A. Awad
No information about this author
et al.
Functional & Integrative Genomics,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 4, 2025
Language: Английский
Current advances in the development of microRNA-integrated tissue engineering strategies: a cornerstone of regenerative medicine
Luis Germán Castañón-Cortés,
No information about this author
Luis Alberto Bravo-Vázquez,
No information about this author
Grecia Santoyo-Valencia
No information about this author
et al.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: Oct. 16, 2024
Regenerative
medicine
is
an
innovative
scientific
field
focused
on
repairing,
replacing,
or
regenerating
damaged
tissues
and
organs
to
restore
their
normal
functions.
A
central
aspect
of
this
research
arena
relies
the
use
tissue-engineered
scaffolds,
which
serve
as
structural
supports
that
mimic
extracellular
matrix,
providing
environment
orchestrates
cell
growth
tissue
formation.
Remarkably,
therapeutic
efficacy
these
scaffolds
can
be
improved
by
harnessing
properties
other
molecules
compounds
have
crucial
roles
in
healing
regeneration
pathways,
such
phytochemicals,
enzymes,
transcription
factors,
non-coding
RNAs
(ncRNAs).
In
particular,
microRNAs
(miRNAs)
are
a
class
tiny
(20–24
nt),
highly
conserved
ncRNAs
play
critical
role
regulation
gene
expression
at
post-transcriptional
level.
Accordingly,
miRNAs
involved
myriad
biological
processes,
including
differentiation,
proliferation,
apoptosis,
well
regeneration,
angiogenesis,
osteogenesis.
On
basis,
over
past
years,
number
studies
demonstrated
integrated
into
create
advanced
platforms
precisely
modulate
cellular
behavior
offer
controlled
targeted
release
optimize
repair
regeneration.
Therefore,
current
review,
we
discuss
most
recent
advances
development
miRNA-loaded
provide
overview
future
outlooks
should
aborded
area
study
order
lay
groundwork
for
clinical
translation
engineering
approaches.
Language: Английский
Application of Cellulose Scaffolds for Drug Delivery and MicroRNAs in Bone Formation and Bone Defect Repair
Regenerative Engineering and Translational Medicine,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 21, 2025
Language: Английский
MicroRNA Nobel Prize: Timely Recognition and High Anticipation of Future Products—A Prospective Analysis
Sarfaraz K. Niazi,
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Matthias Magoola
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International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(23), P. 12883 - 12883
Published: Nov. 29, 2024
MicroRNAs
(miRNAs)
maintain
cellular
homeostasis
by
blocking
mRNAs
binding
with
them
to
fine-tune
the
expression
of
genes
across
numerous
biological
pathways.
The
2024
Nobel
Prize
in
Medicine
and
Physiology
for
discovering
miRNAs
was
long
overdue.
We
anticipate
a
deluge
research
work
involving
repeat
history
prizes
awarded
on
other
RNAs.
Although
miRNA
therapies
are
included
several
complex
diseases,
realization
that
regulate
their
roles
addressing
hundreds
diseases
expected;
but
advancement
drug
discovery
tools,
we
even
faster
entry
new
drugs.
To
promote
this,
provide
details
current
science,
logic,
intellectual
property,
formulations,
regulatory
process
anticipation
many
more
researchers
will
introduce
novel
based
discussion
advice
provided
this
paper.
Language: Английский