Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases

International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(3), P. 741 - 741

Published: Jan. 23, 2020

Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays desirable components of oils with special dietary functional properties. Their therapeutic health-promoting effects have already been established in various chronic inflammatory autoimmune diseases through mechanisms, including modifications cell membrane lipid composition, gene expression, cellular metabolism, signal transduction. The application ω-3 ω-6 PUFAs most common skin has examined numerous studies, but their results conclusions were mostly opposing inconclusive. It seems that combined ω-6, gamma-linolenic acid (GLA), long-chain supplementation exhibits the highest potential diminishing processes, which could be beneficial for management diseases, such as atopic dermatitis, psoriasis, acne. Due to significant population individually-based genetic variations impact metabolism associated metabolites, subsequent responses, at this point, we not recommend strict strategies disease prevention treatment will appropriate all. Well-balanced nutrition additional anti-inflammatory PUFA-based should encouraged a targeted manner individuals need provide better but, importantly, maintain improve overall health.

Language: Английский

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Protective Effects of Omega-3 Fatty Acids in Cancer-Related Complications

Nutrients, Journal Year: 2019, Volume and Issue: 11(5), P. 945 - 945

Published: April 26, 2019

Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and commonly used in the nutritional therapy of cancer patients due to their ample biological effects. PUFAs play essential roles cell signaling structure fluidity membranes. They participate resolution inflammation have anti-inflammatory antinociceptive Additionally, they can act as agonists G protein-coupled receptors, namely, GPR40/FFA1 GPR120/FFA4. Cancer undergo complications, such anorexia-cachexia syndrome, pain, depression, paraneoplastic syndromes. Interestingly, 2017 European Society for Clinical Nutrition Metabolism (ESPEN) guidelines only discuss use omega-3 cancer-cachexia treatment, leaving aside other cancer-related complications that could potentially be managed by PUFA supplementation. This critical review aimed effects possible underlying mechanisms supplementation complications. Data compilation this indicates further investigation is still required assess factual benefits cancer-associated illnesses. Nevertheless, preclinical evidence reveals metabolites might modulate pivotal pathways secondary cancer, indicating a promising field knowledge explored.

Language: Английский

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A critical review on the health benefits of fish consumption and its bioactive constituents

Food Chemistry, Journal Year: 2021, Volume and Issue: 369, P. 130874 - 130874

Published: Aug. 16, 2021

Language: Английский

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Natural Compounds and Products from an Anti-Aging Perspective

Molecules, Journal Year: 2022, Volume and Issue: 27(20), P. 7084 - 7084

Published: Oct. 20, 2022

Aging is a very complex process that accompanied by degenerative impairment in many of the major functions human body over time. This inevitable influenced hereditary factors, lifestyle, and environmental influences such as xenobiotic pollution, infectious agents, UV radiation, diet-borne toxins, so on. Many external internal signs symptoms are related with aging senescence, including skin dryness wrinkles, atherosclerosis, diabetes, neurodegenerative disorders, cancer, etc. Oxidative stress, consequence imbalance between pro- antioxidants, one main provoking factors causing aging-related damages concerns, due to generation highly reactive byproducts oxygen nitrogen species during metabolism, which result cellular damage apoptosis. Antioxidants can prevent these processes extend healthy longevity ability inhibit formation free radicals or interrupt their propagation, thereby lowering level oxidative stress. review focuses on supporting antioxidant system organism balancing diet through consumption necessary amount natural ingredients, vitamins, minerals, polyunsaturated fatty acids (PUFA), essential amino acids, probiotics, plants’ fibers, nutritional supplements, polyphenols, some phytoextracts, drinking water.

Language: Английский

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Marine Natural Products as Innovative Cosmetic Ingredients

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(3), P. 170 - 170

Published: March 8, 2023

Over the course of last 20 years, numerous studies have identified benefits an array marine natural ingredients for cosmetic purposes, as they present unique characteristics not found in terrestrial organisms. Consequently, several marine-based and bioactive compounds are under development, used or considered skin care cosmetics. Despite multitude cosmetics based on sources, only a small proportion their full potential has been exploited. Many industries turned attention to sea obtain innovative marine-derived cosmetics, but further research is needed determine elucidate benefits. This review gathers information main biological targets ingredients, different classes products interest applications, organisms from which such can be sourced. Although phyla varied bioactivities, algae phylum seems most promising presenting many classes. In fact, some these higher bioactivities than commercialized counterparts, demonstrating presented by applications (i.e., Mycosporine-like amino acids terpenoids' antioxidant activity). also summarizes major challenges opportunities faced successfully reach market. As future perspective, we consider that fruitful cooperation among academics could lead more sustainable market through responsible sourcing implementing ecological manufacturing processes, experimenting with inventive recycling reuse programs.

Language: Английский

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Unsaturated fatty acids in natural edible resources, a systematic review of classification, resources, biosynthesis, biological activities and application

Food Bioscience, Journal Year: 2023, Volume and Issue: 53, P. 102790 - 102790

Published: May 29, 2023

Language: Английский

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Innovative Approaches to an Eco-Friendly Cosmetic Industry: A Review of Sustainable Ingredients

Clean Technologies, Journal Year: 2024, Volume and Issue: 6(1), P. 176 - 198

Published: Feb. 8, 2024

Sustainable ingredients in cosmetics have been discussed for the past decade, and COVID-19 pandemic has increased awareness of this significant topic. Consumers are informed vigilant about clean labels, driving necessity sustainability throughout cosmetic production chain. Moreover, nanotechnology green chemistry approaches emerged as innovative perspectives to develop sustainable eco-friendly ingredients. In sense, review, we present examples applications derived from several types sources (i.e., plants, animals, microorganisms, cell cultures, recycled materials/biomaterials). The benefits drawbacks all classes compounds were organized relation novel formulations/products. Finally, addressed on that prioritize safety, with an emphasis exploring ingredients, compounds, or molecules promising areas research development.

Language: Английский

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Recent Advances in Marine-Based Nutraceuticals and Their Health Benefits

Marine Drugs, Journal Year: 2020, Volume and Issue: 18(12), P. 627 - 627

Published: Dec. 9, 2020

The oceans have been the Earth’s most valuable source of food. They now also become a and versatile bioactive compounds. significance marine organisms as natural new substances that may contribute to food sector overall health humans are expanding. This review is an update on recent studies functional seafood compounds (chitin chitosan, pigments from algae, fish lipids omega-3 fatty acids, essential amino acids proteins/peptides, polysaccharides, phenolic compounds, minerals) focusing their potential use nutraceuticals benefits.

Language: Английский

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Nutricosmetics: A brief overview

Phytotherapy Research, Journal Year: 2019, Volume and Issue: 33(12), P. 3054 - 3063

Published: Sept. 3, 2019

The nutricosmetics are products and ingredients that act as nutritional supplements to care skin, nails, hair natural beauty. They work from the inside promote beauty within. Nutricosmetic is latest trend in industry. This tendency rapidly gained many followers because it fits with modern culture: Today, consumers very careful food they introduce into their body, there also an increasing demand for able enhance one's health without side effects significant traction before use. However, nutricosmetic considered effective due historical use word of mouth. Comprehensive analysis global market conducted considering form, end‐user applications, some product components such collagen, peptides, proteins, vitamins, carotenes, minerals, omega‐3 fatty acid reported. Plant extract used described.

Language: Английский

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Lipids from Microalgae for Cosmetic Applications

Cosmetics, Journal Year: 2021, Volume and Issue: 8(2), P. 52 - 52

Published: June 17, 2021

In recent years, there has been considerable interest in using microalgal lipids the food, chemical, pharmaceutical, and cosmetic industries. Several species can accumulate appreciable lipid quantities therefore are characterized as oleaginous. formulations, their derivatives one of main ingredients. Different classes great moisturizing, emollient, softening agents, work surfactants emulsifiers, give consistence to products, color fragrance carriers, act preservatives maintain products integrity, be part molecules delivery system. past, chemicals have widely used but today’s market customers’ demands oriented towards natural products. Microalgae an extraordinary source other many bioactive molecules. Scientists’ attention microalgae cultivation for industrial application is increasing. For high costs associated, commercialization still not very widespread. The possibility use biomass various purposes could make more economically competitive.

Language: Английский

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