Bioengineering,
Journal Year:
2023,
Volume and Issue:
10(5), P. 594 - 594
Published: May 15, 2023
This
study
aimed
to
investigate
the
use
of
organic
fertilizers
instead
modified
f/2
medium
for
Chlorella
sp.
cultivation,
and
extracted
lutein
microalga
protect
mammal
cells
against
blue-light
irradiation.
The
biomass
productivity
content
cultured
in
20
g/L
fertilizer
6
days
were
1.04
g/L/d
4.41
mg/g,
respectively.
These
values
are
approximately
1.3-
1.4-fold
higher
than
those
achieved
with
medium,
cost
per
gram
microalgal
reduced
by
about
97%.
was
further
increased
6.03
mg/g
when
supplemented
mM
urea,
96%.
When
doses
≥1
μM
used
NIH/3T3
cells,
there
a
significant
reduction
levels
reactive
oxygen
species
(ROS)
produced
following
irradiation
treatments.
results
show
that
urea
supplements
has
potential
develop
anti-blue-light
oxidation
products
reduce
economic
challenges
applied
carbon
biofixation
biofuel
production.
Food Production Processing and Nutrition,
Journal Year:
2022,
Volume and Issue:
4(1)
Published: Oct. 13, 2022
Abstract
Seaweed
has
emerged
as
one
of
the
most
promising
resources
due
to
its
remarkable
adaptability,
short
development
period,
and
resource
sustainability.
It
is
an
effective
breakthrough
alleviate
future
crises.
Algal
have
reached
a
high
stage
growth
in
past
years
increased
output
demand
for
seaweed
worldwide.
Several
aspects
global
farming
production
processing
over
last
20
are
reviewed,
such
latest
situation
approaches
farming.
Research
progress
trend
various
application
discussed.
Besides,
challenges
faced
by
also
analyzed,
related
countermeasures
proposed,
which
can
provide
advice
processing.
The
primary
products,
extraction
application,
or
waste
utilization
would
bring
greater
benefits
with
continuous
improvement
applications
fields.
Graphical
Foods,
Journal Year:
2023,
Volume and Issue:
12(20), P. 3878 - 3878
Published: Oct. 23, 2023
Microalgae
are
a
rich
resource
of
lipids,
proteins,
carbohydrates
and
pigments
with
nutritional
health
benefits.
They
increasingly
find
use
as
ingredients
in
functional
foods
feeds
well
cosmetics
agricultural
products
including
biostimulants.
One
their
distinct
advantages
is
ability
to
grow
on
wastewaters
other
waste
streams,
they
considered
an
environmentally
friendly
cheap
method
recover
nutrients
remove
pollutants
from
the
environment.
However,
there
limits
concerning
applications
if
grown
certain
streams.
Within,
we
collate
overview
existing
algal
current
market
scenarios
for
microalgal
along
relevant
legislative
requirements
Europe
United
States.
Microalgal
compounds
interest
extraction
processing
methodologies
summarized,
benefits
caveats
microalgae
cultivated
various
streams
discussed.
Biotechnology for Biofuels and Bioproducts,
Journal Year:
2025,
Volume and Issue:
18(1)
Published: Feb. 14, 2025
Microalgae
are
promising
sources
of
valuable
carotenoids
like
β-carotene
and
astaxanthin
with
numerous
health
benefits.
This
review
summarizes
recent
studies
on
producing
these
in
microalgae
under
different
salinity
light-intensity
conditions,
which
key
factors
influencing
their
biosynthesis.
The
carotenoid
biosynthesis
pathways
microalgae,
involving
the
methylerythritol
phosphate
pathway
chloroplasts,
described
detail.
effects
high
light
stress
stimulating
accumulation
species
Haematococcus
pluvialis
Chromochloris
zofingiensis
synergistic
impact
discussed.
Similarly,
covers
how
induce
production
Dunaliella
salina
other
microalgae.
diverse
health-promoting
properties
β-carotene,
such
as
antioxidant,
antiinflammatory,
anticancer
activities,
highlighted.
Strategies
to
improve
yields
through
environmental
stresses,
two-stage
cultivation,
genetic
engineering,
metabolic
engineering
approaches
evaluated.
Overall,
this
highlights
advancements
reporting
microalgal
capability
produce
level
31.5%
increase
productivity
reaching
18.1
mg/L/day
lacustris.
It
also
explores
novel
biotechnological
strategies,
including
CRISPR-Cas9,
for
enhancing
yield.
Proceedings of the National Academy of Sciences,
Journal Year:
2022,
Volume and Issue:
119(38)
Published: Sept. 12, 2022
Fucoxanthin
is
a
major
light-harvesting
pigment
in
ecologically
important
algae
such
as
diatoms,
haptophytes,
and
brown
(Phaeophyceae).
Therefore,
it
driver
of
global
primary
productivity.
Species
these
algal
groups
are
colored
because
the
high
amounts
fucoxanthin
bound
to
proteins
their
photosynthetic
machineries
enable
efficient
absorption
green
light.
While
structure
fucoxanthin-chlorophyll
has
recently
been
resolved,
biosynthetic
pathway
still
unknown.
Here,
we
identified
two
enzymes
central
this
by
generating
corresponding
knockout
mutants
diatom
Phaeodactylum
tricornutum
that
due
lack
fucoxanthin.
Complementation
with
native
genes
or
orthologs
from
haptophytes
restored
biosynthesis.
We
propose
complete
path
diatoms
based
on
carotenoid
intermediates
vitro
biochemical
assays.
It
substantially
more
complex
than
anticipated
reveals
diadinoxanthin
metabolism
regulatory
hub
connecting
photoprotective
xanthophyll
cycle
formation
Moreover,
our
data
show
evolved
repeated
duplication
neofunctionalization
for
violaxanthin
de-epoxidase
zeaxanthin
epoxidase.
Brown
described
here
instead
use
an
alternative
predicted
involve
fewer
enzymes.
Our
work
represents
step
forward
elucidating
biosynthesis
understanding
evolution,
biogenesis,
regulation
machinery
algae.
Frontiers in Pharmacology,
Journal Year:
2022,
Volume and Issue:
13
Published: Aug. 2, 2022
Fucoxanthin
(FX)
is
a
special
carotenoid
having
an
allenic
bond
in
its
structure.
FX
extracted
from
variety
of
algae
and
edible
seaweeds.
It
has
been
proved
to
contain
numerous
health
benefits
preventive
effects
against
diseases
like
diabetes,
obesity,
liver
cirrhosis,
malignant
cancer,
etc.
Thus,
can
be
used
as
potent
source
both
pharmacological
nutritional
ingredient
prevent
infectious
diseases.
In
this
review,
we
gathered
the
information
regarding
current
findings
on
antimicrobial,
antioxidant,
anti-inflammatory,
skin
protective,
anti-obesity,
antidiabetic,
hepatoprotective,
other
properties
including
bioavailability
stability
characteristics.
This
review
aims
assist
further
biochemical
studies
order
develop
pharmaceutical
assets
products
combination
with
various
metabolites.
Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(8), P. 1451 - 1451
Published: July 26, 2022
The
antioxidant
system
of
the
human
body
plays
a
crucial
role
in
maintaining
redox
homeostasis
and
has
an
important
protective
function.
Carotenoids
have
pronounced
properties
neutralization
free
radicals.
In
skin,
carotenoids
high
concentration
stratum
corneum
(SC)-the
horny
outermost
layer
epidermis,
where
they
accumulate
within
lipid
lamellae.
Resonance
Raman
spectroscopy
diffuse
reflectance
are
optical
methods
that
used
to
non-invasively
determine
carotenoid
SC
vivo.
It
was
shown
by
electron
paramagnetic
resonance
support
entire
status
vivo
neutralizing
radicals
thus,
counteracting
development
oxidative
stress.
This
review
is
devoted
assembling
kinetics
using
non-invasive
spectroscopic
methods.
Factors
contributing
changes
their
influence
on
summarized.
effect
chemotherapy
cancer
patients
presented.
A
potential
antioxidant-based
pathomechanism
chemotherapy-induced
hand-foot
syndrome
method
reduce
its
frequency
severity
discussed.
Marine Drugs,
Journal Year:
2022,
Volume and Issue:
20(8), P. 524 - 524
Published: Aug. 17, 2022
For
more
than
40
years,
marine
microorganisms
have
raised
great
interest
because
of
their
major
ecological
function
and
numerous
applications
for
biotechnology
pharmacology.
Particularly,
Archaea
represent
a
resource
potential
the
identification
new
metabolites
adaptation
to
extreme
environmental
conditions
original
metabolic
pathways,
allowing
synthesis
unique
biomolecules.
Studies
on
archaeal
carotenoids
are
still
relatively
scarce
only
few
works
focused
industrial
scale
production
biotechnological
pharmacological
properties,
while
societal
demand
these
bioactive
pigments
is
growing.
This
article
aims
provide
comprehensive
review
current
knowledge
carotenoid
metabolism
in
medicine.
After
reviewing
ecology
classification
microorganisms,
as
well
cellular
biochemical
characteristics,
this
paper
highlights
most
recent
data
concerning
Archaea,
biological
properties
pigments,
considerations
at
scale.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(14), P. 7603 - 7603
Published: July 11, 2024
This
article
presents
a
groundbreaking
perspective
on
carotenoids,
focusing
their
innovative
applications
and
transformative
potential
in
human
health
medicine.
Research
jointly
delves
deeper
into
the
bioactivity
bioavailability
of
revealing
therapeutic
uses
technological
advances
that
have
to
revolutionize
medical
treatments.
We
explore
pioneering
which
carotenoids
are
used
treat
chronic
diseases
such
as
cancer,
cardiovascular
disease,
age-related
macular
degeneration,
offering
novel
protective
mechanisms
benefits.
Our
study
also
shows
cutting-edge
innovations
carotenoid
extraction
bioavailability,
including
development
supramolecular
carriers
advanced
nanotechnology,
dramatically
improve
absorption
efficacy
these
compounds.
These
not
only
ensure
consistent
quality
but
tailor
therapies
each
patient's
needs,
paving
way
for
personalized
By
integrating
latest
scientific
discoveries
techniques,
this
research
provides
prospective
clinical
establishing
new
benchmark
future
studies
field.
findings
underscore
importance
optimizing
extraction,
administration,
bioactivity,
methods
develop
more
effective,
targeted,
treatments,
thus
visionary
insight
modern
practices.
In
recent
times,
there
has
been
a
revolutionary
surge
in
antioxidant
research,
with
focus
on
harnessing
microalgae
to
enhance
wellness
and
extend
human
longevity.
Microalgae,
diverse
group
of
unicellular
photosynthetic
organisms,
have
emerged
as
promising
sources
natural
antioxidants
due
their
ability
synthesize
various
bioactive
compounds,
including
carotenoids,
polyphenols,
tocopherols.
These
play
pivotal
role
scavenging
free
radicals
reducing
oxidative
stress,
known
contributors
aging
chronic
diseases.
This
review
provides
an
over-view
advancements
understanding
microalgae’s
potential,
covering
biochemical
composition,
extraction
techniques,
purification
methods.
Moreover,
it
delves
into
compelling
vitro
vivo
studies
showcasing
microalgae-derived
antioxidants’
protective
effects
against
damage,
inflammation,
cardiovascular
diseases,
neurodegenerative
disorders.
The
sustainable
cultivation
controlled
environments
further
supports
the
potential
for
large-scale
production
commercialization
compounds.
As
continue
revolutionize
they
hold
immense
promise
developing
novel
preventive
therapeutic
strategies
promote
health
wellbeing.