Effects of light on the quality of honeysuckle during storage based on physico–chemical indicators and chemical composition DOI Creative Commons
Zhen-Ying Liu, Yunxia Cheng, Zhimao Chao

et al.

Arabian Journal of Chemistry, Journal Year: 2023, Volume and Issue: 17(2), P. 105595 - 105595

Published: Dec. 27, 2023

Honeysuckle, as a medicinal and edible substance, has been widely used for thousands of years. However, its quality is easy to change during storage by strong light, high temperature, humidity other inappropriate conditions. In this study, taking light an example, the changes honeysuckle were explored simulated accelerated test. The results showed that after 18 days under (6000 ± 10 Lx), color changed from green-white yellow-white, parameter a* value increased 0.522 4.061, L* 68.51 75.05. contents chlorophyll a, b, carotenoid decreased 90%, 78.67, 75.69%, respectively. Total phenol content 18.200 13.087 GAE mg·g-1, although total flavonoid antioxidant activities fluctuated without significant difference. Except quercetin, chlorogenic acid nine bio-active compounds increased, resulting in higher than before storage, which indicated still had good utilization discoloration. Combined with metabolomics technology, 22 different metabolites related these screened identified, such pheophorbide astilbin, succinic acid. KEGG enrichment analysis oxidative decomposition phenolic pigment components chlorophylls caused chlorosis honeysuckle. summary, honeysuckle, it didn't affect value. Meanwhile, also systematically explains why Chinese pharmacopoeia describes character "green-white or yellow-white".

Language: Английский

Comprehensive study of different grades of Lonicerae japonicae flos: GC-IMS, UPLC-HRMS, and machine learning DOI Creative Commons
Shuang Liu, Hongjing Dong,

Heng Lu

et al.

Applied Food Research, Journal Year: 2025, Volume and Issue: unknown, P. 100760 - 100760

Published: Feb. 1, 2025

Language: Английский

Citations

1
Extraction, Purification, Structural Characteristics, Health Benefits, and Application of the Polysaccharides from Lonicera japonica Thunb.: A Review DOI Creative Commons

Xinpeng Yang,

Aiqi Yu,

Wenjing Hu

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(12), P. 4828 - 4828

Published: June 17, 2023

Lonicera japonica Thunb. is a widely distributed plant with ornamental, economic, edible, and medicinal values. L. phytoantibiotic broad-spectrum antibacterial activity potent therapeutic effect on various infectious diseases. The anti-diabetic, anti-Alzheimer’s disease, anti-depression, antioxidative, immunoregulatory, anti-tumor, anti-inflammatory, anti-allergic, anti-gout, anti-alcohol-addiction effects of can also be explained by bioactive polysaccharides isolated from this plant. Several researchers have determined the molecular weight, chemical structure, monosaccharide composition ratio water extraction alcohol precipitation, enzyme-assisted (EAE) chromatography. This article searched in Chinese Pharmacopoeia, Flora China, Web Science, PubMed, CNKI databases within last 12 years, using “Lonicera. polysaccharides”, “Honeysuckle polysaccharides” as key word, systematically reviewed purification methods, structural characteristics, structure-activity relationship, health benefits to provide insights for future studies. Further, we elaborated potential applications food, medicine, daily industry, such raw material make lozenges, soy sauce toothpaste, etc. review will useful reference further optimization functional products developed polysaccharides.

Language: Английский

Citations

18
Comparative study on chemical constituents of different medicinal parts of Lonicera japonica Thunb. Based on LC-MS combined with multivariate statistical analysis DOI Creative Commons
Xinrui Zhang,

Xiao Yu,

Xiaomei Sun

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(12), P. e31722 - e31722

Published: May 29, 2024

Lonicerae japonicae flos (LJF), caulis (LJC), folium (LF) and fructus (LFR) are derived from Lonicera japonica Thunb., which formed due to different medicinal parts. The efficacy of the 4 materials has similarities differences. However, little attention been paid illustrate differences in perspective phytochemistry. In this study, ultra-high performance liquid chromatography coupled with hybrid quadrupole-orbitrap mass spectrometry (UPLC-Q-Exactive-Orbitrap-MS) was used qualitatively analyze ingredients herbs. A total 86 compounds were plausibly or unambiguously identified, there 54 common components among materials, each kind had its own unique components. On basis qualitative analysis, ultra-performance triple-quadrupole tandem (UPLC-QQQ-MS/MS) quantitatively 31 contained principal component analysis (PCA), orthogonal partial least squares discriminant (OPLS-DA) other multivariate statistical furtherly performed for comparing contents. results showed that samples same parts clustered into one group, significantly different. variable importance projection (VIP) value OPLS-DA model 10 including chlorogenic acid, secologanic isochlorogenic acid A, loganin, lonicerin, loganic secoxyloganin, sweroside, luteolin rhoifolin main difference materials. study not only lays a solid foundation intrinsic quality control effects at phytochemical level, but also provides more rational utilization various L. expansion resources.

Language: Английский

Citations

8
Lonicera japonica Thunb. and its characteristic component chlorogenic acid alleviated experimental colitis by promoting Lactobacillus and fecal short‐chain fatty acids production DOI Creative Commons
Jiebiao Chen,

Wanhua Xu,

Yang Liu

et al.

Food Frontiers, Journal Year: 2024, Volume and Issue: 5(4), P. 1583 - 1602

Published: May 6, 2024

Abstract Ulcerative colitis is intricately linked to intestinal oxidative stress and dysbiosis of the gut microbiota. Lonicera japonica Thunb. (LJ) a traditional edible medical flower in China, chlorogenic acid (CGA) one its characteristic components. However, it remains unclear whether microbiota plays role therapeutic effects LJ GCA on colitis. Here, we first observed that oral administration CGA for 3 weeks dramatically promoted growth Lactobacillus fecal short‐chain fatty acids (SCFAs) production healthy mice. Subsequently, alleviating were explored with dextran sulfate sodium‐induced mice model. The intervention notably alleviated inflammation, barrier impairment, led significant elevation SCFAs. Eventually, key their metabolites was validated by performing transplantation sterile suspensions from CGA‐treated Our findings demonstrated consumption could benefit host both condition beneficial attributed improvement endogenous antioxidant system promotion probiotic SCFAs production. study highlighted great potential be consumed as functional foods provided novel mechanisms which they

Language: Английский

Citations

4
Cloning and functional verification of Geraniol-10-Hydroxylase gene in Lonicera japonica DOI Creative Commons
Shuping Zhang, Zhenhua Liu, Jia Li

et al.

PeerJ, Journal Year: 2025, Volume and Issue: 13, P. e18832 - e18832

Published: Jan. 13, 2025

Geraniol 10-hydroxylase (G10H) is a cytochrome P450 monooxygenase involved in regulation, which the biosynthesis of monoterpene. However, G10H not characterized at enzymatic mechanism and regulatory function Lonicera japonica. A gene related to monoterpenoid, geraniol 10-hydroxylase, has been cloned from medicinal plant The gene, LjG10H, encodes peptide 498 amino acids with predicted molecular weight 54.45 kDa. LjG10H shares homology 72.93-83.90% other plants. Phylogenetic analysis suggests that protein encoded by this belongs family. Tissue-specific expression revealed most highly expressed flowers. Through heterologous E. coli, was purified its catalytic activity studied. results show enzyme can catalyze hydroxylation 10-hydroxygeraniol. Additionally, japonica seedlings silenced reduction monoterpenoid content. This study demonstrates plays an important role biosynthetic pathway iridoids. first article ascribes be associated iridoid. provides theoretical basis for functional regulating iridoid synthesis valuable resource breeding studies.

Language: Английский

Citations

0
Assessing the Potential Distribution of Lonicera japonica in China Under Climate Change: A Biomod2 Ensemble Model-Based Study DOI Creative Commons
Ying Pan, Yanjun Guan,

Shan Lv

et al.

Agriculture, Journal Year: 2025, Volume and Issue: 15(4), P. 393 - 393

Published: Feb. 13, 2025

Lonicera japonica, an importante rsource plant, possesses significant medicinal, economic, and ecological value. To understand its response to climate change optimize conservation utilization, this study employed the Biomod2 ensemble model predict potential distribution under future scenarios identified key environmental factors influencing distribution. The results showed that current climatic conditions, of honeysuckle is primarily concentrated in low-altitude regions central eastern China Sichuan Basin. In scenarios, overall pattern changes less, area highly suitable habitats slightly decreases by 0.80%. Distribution analysis indicated a trend northward migration towards higher latitudes. Temperature-related factors, including temperature seasonality, minimum coldest month, mean quarter, annual temperature, were as dominant affecting significantly improved precision accuracy suitability predictions compared single models, providing scientific basis for predicting geographic establishing utilizing cultivation China.

Language: Английский

Citations

0
GC-MS, LC-MS, and network pharmacology analysis to investigate the chemical profiles and potential pharmacological activities in flower buds and flowers of Lonicera japonica Thunb DOI Creative Commons
Kai Tong, Lingyun Dai, W. B. Rui

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(4), P. e0320293 - e0320293

Published: April 23, 2025

Lonicera japonica Thunb. ( L. ) is an edible-medicinal herb. While the flower buds of are commonly utilized for medicinal purposes, flowers often overlooked. However, it has been discovered that contain higher levels certain active compounds compared to buds. Despite this finding, there have no reports on potential differences in pharmacological efficacy between these compounds. Utilizing results from GC-MS and LC-MS, a total 335 differential were identified, which 247 complied with Lipinski’s Rule Five concerning properties. Among these, 101 upregulated buds, while 146 flowers. Network pharmacology analysis revealed targeted 143 185 core targets, respectively, 116 being duplicates. The target proteins among duplicate targets primarily involved pathways related cancer, lipid atherosclerosis, hepatitis B, proteoglycans Alzheimer’s disease. Meanwhile, hub enriched distinct associated human T-cell leukemia virus 1 infection, focal adhesion, thyroid hormone signaling pathway, fluid shear stress atherosclerosis. Molecular docking indicated exhibited strong binding affinity targets. This study provides insights into components (flower buds) non-medicinal (flowers) raw materials predicting mechanisms action establishing basis more rational utilization

Language: Английский

Citations

0
Bis-Iridoids: Occurrence, Chemophenetic Evaluation and Biological Activities—A Review DOI Creative Commons
Claudio Frezza, Alessandro Venditti, Daniela De Vita

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(23), P. 5646 - 5646

Published: Nov. 28, 2024

In this work, the first review paper about

Language: Английский

Citations

2
Flexible substrate‐based mass spectrometry platform for in situ non‐destructive molecular imaging of living plants DOI Creative Commons
Guanhua Zhang, Han Zheng, Xiao Wang

et al.

Plant Biotechnology Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Summary Monitoring and localizing molecules on living plants is critical for understanding their growth, development disease. However, current techniques molecular imaging of often lack spatial information or require tedious pre‐labelling. Here, we proposed a novel platform that combines sliver nanowire‐doped Ti 3 C 2 MXene (Ag NWs@MXene) flexible film substrate with laser desorption/ionization mass spectrometry (AMF‐LDI‐MSI) to study the distribution biomolecules surface plants. This overcomes MSI challenges posed by difficult‐to‐slice plant tissues (e.g., tough water‐rich roots fragile flowers) enables precisely transfer visualize molecule. Comparisons measurement results those from matrix‐assisted LDI‐MSI (MALDI‐MSI) technology demonstrate accuracy reliability platform. Biocompatibility evaluations indicated without observable adverse effects health The growth disease‐associated signalling molecules, such as choline, organic acids carbohydrates, can be in situ non‐destructively detected surfaces plants, which important tracking diseased areas. AMF‐LDI‐MSI serve promising tool label‐free, non‐destructive monitoring functional perspective.

Language: Английский

Citations

1
Application of metabolomics in quality control of traditional Chinese medicines: a review DOI Creative Commons

Peiran Ji,

Xinquan Yang,

Xiangsheng Zhao

et al.

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 15, 2024

Plant metabolites are the components endowing traditional Chinese medicine (TCM) with therapeutic effects, and, simultaneously, they primary targets for quality control. From germplasm selection and origin determination to field management, growth duration, harvesting processing, finally, storage transportation, each step profoundly influences TCM quality. The complexity of these plant or herb poses numerous control challenges. Metabolomics, as a comprehensive systematic approach, has demonstrated value in this field. This technique not only meets requirements studying complex mechanisms but also significant advantages identifying components, including active components. Therefore, article, several key factors affecting chemical characteristics traits TCM, their origin, period, medicinal parts, processing methods, researched. Additionally, current challenges integrating metabolomics other omics technologies (transcriptomics, spatial metabolomics, etc.) discussed. Furthermore, future development trends prospects highlighted. With continuous deepening research ongoing updates technological capabilities, will play an increasingly important role providing more scientific robust support assurance safety evaluation.

Language: Английский

Citations

1