Pathogenic bacteria significantly increased under oxygen depletion in coastal waters: A continuous observation in the central Bohai Sea

Frontiers in Microbiology, Journal Year: 2022, Volume and Issue: 13

Published: Nov. 21, 2022

The spread of pathogenic bacteria in coastal waters endangers the health local people and jeopardizes safety marine environment. However, their dynamics during seasonal hypoxia Bohai Sea (BHS) have not been studied. Here, were detected from 16S rRNA gene sequencing database used to explore driving factors with progressively deoxygenating BHS. Our results showed that all samples, accounting for 0.13 24.65% total number prokaryotic sequences each sample. Pathogenic Proteobacteria was dominated followed by Firmicutes, Actinobacteria, Tenericutes, Bacteroidetes, etc. β-diversity analysis are highly temporally heterogeneous regulated environmental factors. According RDA analysis, these variations may be influenced salinity, ammonia, DO, phosphate, silicate, Chl a. Additionally, surface water zone found significantly separated August. vertical distribution bacterial communities is several variables, including DO nutrition. It noteworthy zones increase abundance certain genera, especially Vibrio Arcobacter, stability community increased May These phenomena indicate central threatened an increasingly serious And developing future intensify this phenomenon pose a more threat human health. This study provides new insight into changes aquatic ecosystems help make effective policies control bacteria.

Language: Английский

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Sodium salt of boron-substituted first keggin-type polyoxometalate; synthesis, crystal structure and investigation of antimicrobial activities

Polyhedron, Journal Year: 2025, Volume and Issue: unknown, P. 117453 - 117453

Published: Feb. 1, 2025

Language: Английский

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Detection, relatedness and environmental sources of emerging Legionella longbeachae infections in Finland, 1989-2024

Diagnostic Microbiology and Infectious Disease, Journal Year: 2025, Volume and Issue: 112(2), P. 116788 - 116788

Published: March 6, 2025

Legionella longbeachae is an emerging cause of Legionnaires' disease in Europe. We analysed data from the National Infectious Disease Register (NIDR) and Reference Laboratory database to characterize L. infections diagnostics Finland. A total 41 patient cases, mainly gardeners' pneumonias hand wounds, were reported during 1989-2024, with a significant increase after 2019. Patient interviews environmental sampling linked compost, potting soil or outdoor activities. Whole genome sequencing (WGS) confirmed identical isolates three cases revealed several clusters among non-related isolates. Compared caused by other species, had distinct characteristics, including higher median age (64 vs. 56 yrs.), fatality (15 % 8 %), more extrapulmonary (12 1 %) proportion females (44 35 %). The genetic relatedness high clonality suggest common reservoirs.

Language: Английский

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Legionnaires’ disease: A review of emerging public health threats

International Journal of One Health, Journal Year: 2025, Volume and Issue: unknown, P. 62 - 77

Published: March 1, 2025

Background and Aim: Legionnaires’ disease (LD), caused by the Gram-negative bacterium Legionella pneumophila, has emerged as a significant public health concern due to its rising incidence high morbidity mortality rates. This review comprehensively examines etiology, epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, prevention of LD. The thrives in aquatic environments, often within biofilms protozoan hosts, contributing resilience widespread distribution natural man-made water systems. Transmission primarily occurs through inhalation contaminated aerosols, with immunocompromised individuals, elderly, smokers being at heightened risk. Clinically, LD presents severe pneumonia systemic involvement, diagnosis relies on culture, urinary antigen tests, molecular methods. treatment landscape is dominated macrolides fluoroquinolones, emerging research into alternative therapies combat antimicrobial resistance. Effective strategies, including rigorous management practices infection control measures, are vital mitigating risk outbreaks. aims enhance awareness inform initiatives elucidating complex interplay between bacterial virulence, host factors, environmental conditions that contribute transmission persistence. A better understanding these dynamics crucial for developing robust ultimately reducing global burden this potentially life-threatening disease. Keywords: disease, pneumonia, health, waterborne pathogens.

Language: Английский

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Legionella spp. in a Dental Office—Current State of Knowledge

Pathogens, Journal Year: 2025, Volume and Issue: 14(6), P. 512 - 512

Published: May 22, 2025

Conditions in dental offices are conducive to Legionella pneumophila infections. This is mainly related the use of a unit daily clinical work, which basic equipment office. Water discharged from waterlines (DUWLs) and working tips generates splatter/spatter bioaerosol, constituting main sources potential infection posing health threat both patients professional staff. article presents narrative review on presence risk associated with spp., particularly species L. pneumophila, paper summarizes current knowledge offers readers practical references, especially useful everyday practice.

Language: Английский

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Concept about the Virulence Factor of Legionella

Microorganisms, Journal Year: 2022, Volume and Issue: 11(1), P. 74 - 74

Published: Dec. 27, 2022

Pathogenic species of Legionella can infect human alveolar macrophages through Legionella-containing aerosols to cause a disease called Legionellosis, which has two forms: flu-like Pontiac fever and severe pneumonia named Legionnaires’ (LD). is an opportunistic pathogen that frequently presents in aquatic environments as biofilm or protozoa parasite. Long-term interaction extensive co-evolution with various genera amoebae render Legionellae pathogenic humans also generate virulence differentiation heterogeneity. Conventionally, the proteins involved initiating replication processes macrophage infections have been regarded factors linked pathogenicity. However, because some are associated infection macrophages, it would be more accurate classify them survival rather than factors. Given molecular basis variations among non-pathogenic, pathogenic, highly not yet elaborated from perspective factors, comprehensive explanation how infects its natural hosts, protozoans, accidental essential show novel concept regarding factor Legionella. In this review, we overviewed development protozoa, function conventional host’s innate immune system, regulating host response, before discussing probably new definition for

Language: Английский

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Gram-negative bacteria

Infectious Diseases, Journal Year: 2023, Volume and Issue: unknown, P. 63 - 118

Published: Jan. 1, 2023

This chapter discussed gram-negative bacteria, which is a very broad group and includes several bacteria. The starts with the classification of represented as tree chart. In this chapter, description each bacterium in group, disease they cause, signs symptoms disease, virulent factors, diagnosis, differential selection appropriate antibiotics are discussed. Obligate intracellular spirochetes, acid fast bacteria no cell walls also included chapter. Anaerobic Chapter 3 not here. Bacteria classified according to traditional clinical for better understanding.

Language: Английский

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Detection of Legionella pneumophila bacteria from water sources in Palembang City, Indonesia

Biodiversitas Journal of Biological Diversity, Journal Year: 2024, Volume and Issue: 25(4)

Published: April 19, 2024

Abstract. Kautsar R, Fauziyah S, Aquaresta F, Widya AM, Fajar NS, Damayanti M, Sucipto TH. 2024. Detection of Legionella pneumophila bacteria from water sources in Palembang City, Indonesia. Biodiversitas 25: 1499-1504. is a pathogenic bacterial genus that causes legionellosis. This gram-negative which often found warm and humid aquatic environments. spp. infection occurs due to inhalation aerosols contaminated with Until now, legionellosis still crucial public health problem the world. Therefore, it necessary take preventive measures detect presence as early possible. study aimed well samples drinking City using Nested PCR method. The primers used this are specific amplify mip gene. amplification results showed 2 22 were positively L. pneumophila. These positive came samples. Based on physical parameters, all safe for consumption because they have normal temperature, odorless clear. Meanwhile, based chemical pH below maximum threshold.

Language: Английский

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Legionella pneumophila Presence in Dental Unit Waterlines: A Cultural and Molecular Investigation in the West Bank, Palestine

Tropical Medicine and Infectious Disease, Journal Year: 2023, Volume and Issue: 8(11), P. 490 - 490

Published: Oct. 30, 2023

A Legionella pneumophila bacterium is ubiquitous in water distribution systems, including dental unit waterlines (DUWLs). Legionellosis atypical pneumonia, Legionnaires' disease (LD) and the less acute form of Pontiac fever. occurs as a result inhalation/aspiration aerosolized Legionella-contaminated by susceptible patients, health workers, dentists. In this study, we undertook to determine prevalence biofilm samples from Tap DUWLs collected five sites clinics faculties across West Bank. Water were tested for physical chemical parameters. The study included 185 samples, 89 (48%) 96 (52%) swabs, which analyzed cultivation-dependent analysis (CDA) cultivation-independent technique (CIA). Also, partial sequencing 16S rRNA gene fifteen L. isolates was performed quality assurance identification. isolated 28 (15%) using CDA detected 142 (77%) CIA. abundance culturable low DUWL sampling (range: 27-115 CFU/Liter). PCR 5× more sensitive than culture technique. Sg 1 (75%) isolates, while (25%) 2-14. All sequenced identified ≥ 94.5%. phylogenetic tree showed that branch clearly distinguished other branches. These results show examined are contaminated with pneumophila. This finding reveals serious potential risk infection immunocompromised patients dentists' post-exposure.

Language: Английский

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Legionella

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1547 - 1557

Published: Jan. 1, 2024

Language: Английский

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