Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 133 - 150
Published: Oct. 25, 2024
Pesticide Biochemistry and Physiology, Journal Year: 2025, Volume and Issue: unknown, P. 106398 - 106398
Published: April 1, 2025
Language: Английский
Citations
0
Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1767 - 1767
Published: June 5, 2024
The nutritional status of the mother-to-be has a key impact on proper development fetus. Although all nutrients are important for developing baby, recent research indicates importance adequate choline intake during periconceptional period, pregnancy, and lactation. Choline plays role in biosynthesis cell membranes, supporting liver function, neurotransmission, brain development, DNA histone methylation. participates formation child’s nervous system, supports its cognitive reduces risk neural tube defects. human body is incapable producing sufficient to meet needs; therefore, it must be obtained from diet. Current data indicate that most women their reproductive years do not achieve recommended daily choline. presented narrative review educating mothers-to-be thereby increasing awareness effects maternal child health, which can lead more aware healthy pregnancy development.
Language: Английский
Citations
3
Frontiers in Physiology, Journal Year: 2023, Volume and Issue: 14
Published: June 1, 2023
Zebrafish ( Danio rerio ) have emerged as a powerful model to study the gut microbiome in context of human conditions, including hypertension, cardiovascular disease, neurological disorders, and immune dysfunction. Here, we highlight zebrafish tool bridge gap knowledge linking physiological homeostasis cardiovascular, neural, systems, both independently an integrated axis. Drawing on studies date, discuss challenges microbiota transplant techniques gnotobiotic husbandry practices. We present advantages current limitations research use identification microbial enterotypes health disease. also versatility further explore function conditions relevant dysbiosis reveal novel therapeutic targets.
Language: Английский
Citations
9
Nutrients, Journal Year: 2023, Volume and Issue: 15(22), P. 4849 - 4849
Published: Nov. 20, 2023
Feeding intolerance (FI) is a significant concern in the care of preterm infants, impacting their growth and development. We previously reported that FI linked to lower fecal calprotectin (FC) levels. This study aims explore postnatal dynamics interplay between microbiota, metabolic profiles, host immunity infants with without FI.Infants gestational age <32 weeks or birth weight <1500 g were enrolled at Children's Hospital Fudan University January 2018 October 2020. Weekly samples analyzed for bacterial profiling, metabolome, levels, exploring longitudinal development interrelationships.Of 118 very studied, 48 showed FI. These experienced an interrupted microbial-immune trajectory, particularly 3-4 age, marked by reduced abundance, alpha diversity, FC Metabolic changes pronounced 3 6 weeks. Pantothenic acid two polyamine metabolites closely associated abundance levels negatively correlated duration attain full enteral feeding.FI demonstrated compromised microbiome-immune interactions, potentially influenced specific metabolites. research underscored importance early microbial pathogenesis infants.
Language: Английский
Citations
7
Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1564 - 1564
Published: July 31, 2024
Gestational diabetes mellitus (GDM) is an important health issue, as it connected with adverse effects to the mother well fetus. A factor of essence for pathology this disorder gut microbiota, which seems have impact on development and course GDM. The role microbiota maternal reproductive all changes that happen during pregnancy neonatal period high interest. correct establishment maturation importance basic biological systems. aim study provide a systematic review literature effect GDM neonates, possible links morbidity mortality neonates born mothers Systematic research took place in databases including PubMed Scopus until June 2024. Data involved demographics, methodology, were derived divided based patients exposure or conducted online revealed 316 studies, only 16 met criteria included review. Research from studies showed great heterogeneity varying findings at level α β diversity enrichment depletion phylum, gene, species, operational taxonomic units infants ways are altered due remain largely unclear require further investigation. Future needed explore clarify these mechanisms.
Language: Английский
Citations
2
Social Science & Medicine, Journal Year: 2024, Volume and Issue: 360, P. 117338 - 117338
Published: Sept. 12, 2024
The widespread discrimination against individuals with obesity often stems from a simplistic perception of as mere consequence personal choices overeating and insufficient physical activity. This reductionist fails to acknowledge the complexity epidemic obesity, which extends beyond diet exercise decisions. concept appetite self-regulation (ASR) has been explored crucial element in identifying obesogenic behavioral approaches food. Although an extensive understanding ASR children is essential early precursor modifiable factor influencing prevailing view eating solely matter cognitive processing tends overlook interacting systems influences. narrow approach attributes lack voluntary self-control food consumption while neglecting account for biological, psychological, social influences implicated developmental processes ASR, may further contribute stigmatization obesity. current critical analysis provides comprehensive framework that could guide future studies testable hypotheses, outlining pathways interactions among biopsychosocial systems, all development childhood. Adopting perspectives allows holistic investigating accounts intricate between biological (B), psychological (P), (S) factors influential manifestation ASR.
Language: Английский
Citations
2
Biomolecules, Journal Year: 2024, Volume and Issue: 14(10), P. 1254 - 1254
Published: Oct. 4, 2024
There is significant communication and interdependence among the gut, microbiome, brain during development. Diseases, such as necrotizing enterocolitis (NEC), highlight how injury to immature gastrointestinal tract leads long-term neurological consequences, due vulnerabilities of in early stages life. A better understanding developing gut–microbiota–brain axis needed both prevent treat devastating consequences these disease processes. The a bidirectional pathway that includes metabolic, nervous, endocrine, immune components. In this review, we discuss gut development, microbiome colonization maturation, interactions influence neurodevelopment context NEC. We describe components gut–brain an integral member relationship. Finally, explore derangements within affect normal development function other systems neurodevelopmental for patients.
Language: Английский
Citations
2
Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14
Published: April 18, 2023
Introduction Owing to advancements in non-invasive magnetic resonance imaging, many studies have repeatedly showed that diabetes affects the central nervous system presence of peripheral neuropathy, suggesting a common or interacting pathological mechanism for both complications. Methods We aimed investigate role abnormal gut microbiota rats with diabetic neuropathy (DPN) combined cognitive dysfunction. Glucose-compliant nerve conduction deficits were screened as successful group DPN rats. The was then divided into impairment (CD) and normal function (NCD) based on results Novel object recognition test. Rat feces collected 16S rRNA gene sequencing intestinal flora. Results Discussion revealed abnormalities Firmicutes , Ruminococcaceae Bacteroidia Actinobacteria-like microorganisms may induce complicated by
Language: Английский
Citations
6
Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14
Published: May 4, 2023
Perioperative neurocognitive disorders (PND) is a common surgical anesthesia complication characterized by impairment of memory, attention, language understanding and social ability, which can lead to decline in the quality life patients, prolong hospitalization period increase mortality rate. PND has high incidence rate, great impact on postoperative recovery caused heavy economic burden society families. In recent years, become an important public health problem. The risk population more prone gut microbiota imbalance, may also affect inflammatory response central nervous system through microbiota-gut-brain axis. Meanwhile, Neuroinflammation immune activation are mechanisms PND. Regulating probiotics or fecal bacteria transplantation significantly reduce neuroinflammation, abnormal prevent occurrence This review summarizes research progress PND, providing basis for prevention treatment
Language: Английский
Citations
6
Research in autism spectrum disorders, Journal Year: 2024, Volume and Issue: 117, P. 102440 - 102440
Published: July 5, 2024
Language: Английский
Citations
1