Dysbiosis and allergy as a background of chronic rhinosinusitis in preschool children DOI Creative Commons
Katarzyna Molińska, Paweł Majak

Pediatria i Medycyna Rodzinna, Journal Year: 2023, Volume and Issue: 19(2), P. 73 - 77

Published: Aug. 28, 2023

Allergic diseases and chronic inflammatory of the respiratory system, such as asthma or rhinosinusitis, continue to pose a real challenge modern medicine. The causes growing problem generated by these is thought be in interaction genes environment. In light current knowledge, it seems that environmentally dependent between airway microbiota ecosystem epithelium able shape functions local immune producing number molecular clinical consequences. this paper, an attempt was made describe role composition disorders (dysbiosis) upper tract allergies development chronić rhinosinusitis children. research results obtained Polish cohort young children diagnosed with without concomitant are summarised. Some presented features secondary dysbiosis, which associated sensitisation house dust mite allergens. It noted frequent courses antibiotic therapy correlated dysfunction, reducing biodiversity. also observed patients suffering from had specific dysbiosis tract. characterised altered proportion main types bacteria expressed reduced Patescibacteria/Actinobacteria ratio, constituting independent factor study group, similar atopy perception sweet taste. An identify possible therapeutic prophylactic interventions treat prevent rhinosinusitis.

Language: Английский

Global landscape of COVID-19 research: a visualization analysis of randomized clinical trials DOI Creative Commons
Sa’ed H. Zyoud

Clinical and Experimental Medicine, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 22, 2024

Abstract The emergence of COVID-19 in 2019 has resulted a significant global health crisis. Consequently, extensive research was published to understand and mitigate the disease. In particular, randomized controlled trials (RCTs) have been considered benchmark for assessing efficacy safety interventions. Hence, present study strives comprehensive overview landscape pertaining RCTs COVID-19. A bibliometric analysis performed using Scopus database. search parameters included articles from 2020 2022 keywords specifically related RCTs. data were analyzed various indicators. volume publications, contributions countries institutions, funding agencies, active journals, citation analysis, co-occurrence future direction analyzed. total 223,480 concerning published, with 3,727 them ten most productive collectively produced 75.8% documents, United States leading way by contributing 31.77%, followed UK 14.03% ( n = 523), China 12.96% 483) Canada 7.16% 267). Trials 173, 4.64%), BMJ Open 81, 2.17%), PLOS One 73, 1.96%) JAMA Network 53, 1.42%) journals publishing identified four clusters areas: effectiveness vaccines, mental strategies cope impact pandemic, use monoclonal antibodies treat patients COVID-19, systematic reviews meta-analyses research. This paper offers detailed examination environment their context pandemic. body findings found generated collaborative efforts multiple countries, organizations. predominant areas encompassed health, antibodies, reviews. information potential aid researchers, policymakers, funders discerning weakness establishing priority.

Language: Английский

Citations

6
An Emerging Foodborne Pathogen Spotlight: A Bibliometric Analysis and Scholarly Review of Escherichia coli O157 Research DOI Creative Commons
Himanshu Jangid, Deepak Kumar, Gaurav Kumar

et al.

Antibiotics, Journal Year: 2024, Volume and Issue: 13(1), P. 60 - 60

Published: Jan. 8, 2024

Foodborne infections pose a substantial global threat, causing an estimated 600 million illnesses and resulting in approximately 420,000 deaths annually. Among the diverse array of pathogens implicated these infections, Escherichia coli (E. coli), specifically O157 strain O157), emerges as prominent pathogen associated with severe outbreaks. This study employs comprehensive bibliometric analysis scholarly review focused on E. research. The highlights significant role played by United States research domain. Further exploration underscores noteworthy contributions researcher Doyle MP, whose body work, consisting 84 documents impressive H-Index 49, reflects their impact field. Recent trends indicate discernible shift towards innovative detection methods, exemplified adoption CRISPR-CAS Loop-Mediated Isothermal Amplification. Moreover, high-throughput whole-genome sequencing techniques are gaining prominence for expeditious pathogenic strains. Scientists increasingly exploring antimicrobial agents, including phage therapy, to address challenges posed antibiotic-resistant strains, thereby addressing critical concerns related multi-drug resistance. provides vital insights into dynamic landscape It serves valuable resource researchers, policymakers, healthcare professionals dedicated mitigating outbreaks advancing public health strategies.

Language: Английский

Citations

5
Physical Exercise and the Gut Microbiome: A Bidirectional Relationship Influencing Health and Performance DOI Open Access

Sanish Varghese,

Shrinidhi Rao,

A. Khattak

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3663 - 3663

Published: Oct. 28, 2024

Background/Objectives: The human gut microbiome is a complex ecosystem of microorganisms that can influence our health and exercise habits. On the other hand, physical also impact microbiome, affecting health. Our narrative review examines bidirectional relationship between activity as well potential for targeted probiotic regimens to enhance sports performance. Methods: We conducted comprehensive literature select articles published up till January 2024 on topics exercise, sports, probiotics, microbiota from major scientific databases, incorporating over 100 studies. Results: found varies with type intensity exercise. Moderate promotes healthy immune system, while high-intensity long duration cause leaky consequent systemic inflammation, which may disrupt microbial balance. Combining aerobic resistance training significantly affects bacterial diversity, linked lower prevalence chronic metabolic disorders. Furthermore, enhances increases SCFA production, improves nutrient utilization, modulates neural hormonal pathways, improving barrier integrity. findings showed supplementation associated decreased enhanced performance, fewer gastrointestinal disturbances, suggesting mutually influential. Conclusions: exemplified by how promote beneficial bacteria potentially ability through various mechanisms. These underscore importance adding tailored consider individual profiles into programs.

Language: Английский

Citations

5
Human gut microbiome determining athletes’ performance: an insight from genomic analysis DOI

Shih Chung Cheng,

Chieh Chang, Yen‐Cheng Chen

et al.

Ecological Genetics and Genomics, Journal Year: 2025, Volume and Issue: unknown, P. 100327 - 100327

Published: Jan. 1, 2025

Language: Английский

Citations

0
Visualization of Simulation-Based Training in Otolaryngology: A Bibliometric Analysis DOI Creative Commons
Wenqi Yang, Xiaowei Zhang, Yuzhe Kong

et al.

Heliyon, Journal Year: 2025, Volume and Issue: 11(6), P. e42678 - e42678

Published: Feb. 24, 2025

Language: Английский

Citations

0
Gut microbiota and autism spectrum disorders: where do we stand? DOI Creative Commons
Sa’ed H. Zyoud,

Muna Shakhshir,

Amani S. Abushanab

et al.

Gut Pathogens, Journal Year: 2023, Volume and Issue: 15(1)

Published: Oct. 25, 2023

Children with autism spectrum disorder (ASD) often have digestive problems and microbial imbalances in their guts, suggesting that these conditions may play a role the development of disorder. Scopus-based research on gut microbiota ASD was examined this bibliometric analysis to shed light current state identify potential hotspots for future work area.We searched documents from Scopus database reference citation collect published data 2003 2022. The downloaded document records were exported VOSviewer v.1.6.19 examine visualize collaboration between countries determine hotspots.The search yielded 958 articles specifically dedicated ASD. number publications field increased rapidly after 2013, peak United States (n = 267; 27.87%) most active country, followed by China 171; 17.85%) Italy 96; 10.02). International observed, USA playing central role. University College Cork, Ireland, productive institution 24; 2.51%). National Natural Science Foundation funding agency 76; 7.93%). Nutrients journal had highest 28; 2.92%). related highly cited, an h-index 108. themes identified focused modulation as therapy children gut-brain axis dysfunction ASD.In recent years, study its association has garnered considerable interest emergent study. results substantially enhance our understanding knowledge landscape illuminate avenues research. It is essential emphasize significance devoting more resources newest promising areas, such investigating therapeutic benefits modulating intestinal This enormous merits intensified focus investigation.

Language: Английский

Citations

6
Exercise Affects Mucosa-Associated Microbiota and Colonic Tumor Formation Induced by Azoxymethane in High-Fat-Diet-Induced Obese Mice DOI Creative Commons

Shogen Yo,

Hiroshi Matsumoto, Tingting Gu

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(5), P. 957 - 957

Published: May 9, 2024

The only reliable factor that reduces the risk of colorectal carcinogenesis is physical activity. However, underlying mechanisms remain unclear. In this study, we examined effects activity against gut microbiota, including mucosa-associated microbiota (MAM) on azoxymethane-induced tumors in obese mice. We divided subjects into four groups: normal diet (ND), high-fat (HFD), ND + exercise (Ex), and HFD Ex groups. group performed treadmill for 20 weeks. Thereafter, fecal colonic mucus samples were extracted analysis. DNA was collected from feces mucosa, V3–V4 amplicon sequencing analysis 16SrRNA gene using MiSeq. had significantly more polyps than (ND 6.5 ± 1.3, 11.4 1.5, p < 0.001), addition suppressed number groups 2.8 2.5, 0.05). showed lower concentrations succinic, acetic, butyric, propionic acids (mg/g) feces, compared with (succinic acid 0.59, 0.17; acetic 0.63, 2.41; 0.10, 0.47; N-butyric 0.31, 0.93). case ND, succinic butyric tended to decrease 0.17, 0.12; 0.93, 0.74 0.74). Succinic acid, levels group; both samples, Butyricicoccus Lactobacillus group. Akkermansia increased Diet affected tumors. Furthermore, alter intestinal MAM, which may be involved tumor development.

Language: Английский

Citations

2
Unveiling the hidden world of gut health: Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota DOI Open Access
Sa’ed H. Zyoud,

Muna Shakhshir,

Amani S. Abushanab

et al.

World Journal of Clinical Cases, Journal Year: 2023, Volume and Issue: 11(26), P. 6132 - 6146

Published: Sept. 8, 2023

The gut microbiota plays a crucial role in gastrointestinal and overall health. Randomized clinical trials (RCTs) play advancing our knowledge evaluating the efficacy of therapeutic interventions targeting microbiota.To conduct comprehensive bibliometric analysis literature on RCTs involving microbiota.Using tools, descriptive cross-sectional investigation was conducted scholarly publications concentrated related to microbiota, spanning years 2003 2022. study used VOSviewer version 1.6.9 examine collaboration networks between different countries evaluate frequently employed terms titles abstracts retrieved publications. primary objective this identify key research areas focal points associated with microbiota.A total 1061 relevant articles were identified from 24758 published number showed notable increase over time, positive correlation (R2 = 0.978, P < 0.001). China (n 276, 26.01%), United States 254, 23.94%), Kingdom 97, 9.14%) leading contributing countries. Københavns Universitet 38, 3.58%) Dankook University 35, 3.30%) top active institutions. co-occurrence shows current trends important topics, such as obesity safety fecal transplantation, effects dietary humans.The highlights rapid growth importance that involve microbiota. This provides valuable insight into trends, identifies players, outlines potential future directions field. Additionally, topics critical advancement science provided insights

Language: Английский

Citations

5
Exercise and the gut microbiome: implications for supportive care in cancer DOI
Nicolas H. Hart, Matthew P. Wallen, M. Farley

et al.

Supportive Care in Cancer, Journal Year: 2023, Volume and Issue: 31(12)

Published: Nov. 28, 2023

Language: Английский

Citations

4
A 10-year Scientometric Study of the Emerging Patterns and Spatial–Temporal Trends of Probiotics in Dentistry DOI Open Access
Daniel Alvítez-Temoche, Frank Mayta–Tovalino, Arnaldo Munive-Degregori

et al.

The Journal of Contemporary Dental Practice, Journal Year: 2024, Volume and Issue: 24(12), P. 981 - 986

Published: Jan. 31, 2024

Aim: To perform a bibliometric analysis of the scientific production related to use probiotics in oral health.Materials and methods: A retrospective, descriptive, observational study with scientometric approach was conducted.Metadata from articles were retrieved Web Science (WoS) Core Collection analyzed using Medical Subject Headings (MeSH) Emtree terms.The search strategy included terms health, published between 2013 2022 analyzed.Different indicators used analyze production, impact, network collaboration.Results: total 485 241 sources, an average annual growth rate 10.72%.The manuscripts received citation per doc 15.2.Authors collaborated on 5.76 coauthors paper.The number increased progressively 2022.The year had highest (90), while only 36 published.There progressive decrease citations article, 32.44 2.41 2022. Conclusion:The dentistry has grown steadily, most productive countries United States, Italy, China.The importance international collaborations need for more research this field is emphasized.Clinical significance: The findings may help researchers identify areas that require further lead rapid efficient advances improve health.Its clinical lies its value ability inform guide future advance science.

Language: Английский

Citations

0