Microbial Dysbiosis in the Skin Microbiome and Its Psychological Consequences
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(9), P. 1908 - 1908
Published: Sept. 19, 2024
The
homeostasis
of
the
skin
microbiome
can
be
disrupted
by
both
extrinsic
and
intrinsic
factors,
leading
to
a
state
dysbiosis.
This
imbalance
has
been
observed
at
onset
persistent
diseases
that
are
closely
linked
mental
health
conditions
like
anxiety
depression.
narrative
review
explores
recent
findings
on
relationship
between
pathophysiology
specific
disorders,
including
acne
vulgaris,
atopic
dermatitis,
psoriasis,
wound
infections.
Additionally,
it
examines
psychological
impact
these
emphasizing
their
effect
patients’
quality
life
association
with
significant
consequences,
such
as
anxiety,
depression,
stress,
suicidal
ideation
in
most
severe
cases.
Language: Английский
Electrolyte Imbalances and Metabolic Emergencies in Obesity: Mechanisms and Clinical Implications
Diseases,
Journal Year:
2025,
Volume and Issue:
13(3), P. 69 - 69
Published: Feb. 24, 2025
Electrolyte
imbalances
are
a
frequently
overlooked
yet
critical
component
of
obesity-related
metabolic
dysfunction,
contributing
to
an
increased
risk
cardiovascular
disease,
kidney
impairment,
and
emergencies
such
as
diabetic
ketoacidosis
(DKA),
hyperosmolar
hyperglycemic
state
(HHS),
acute
injury
(AKI).
These
disturbances
arise
from
insulin
resistance,
chronic
inflammation,
hormonal
dysregulation,
renal
leading
sodium
retention,
potassium
depletion,
deficiencies
in
calcium
magnesium
homeostasis.
Managing
electrolyte
is
essential
obesity
management,
exacerbate
hypertension,
acidosis,
neuromuscular
complications,
resistance.
This
review
explores
the
pathophysiology
their
impact
on
fluid
balance,
acid–base
status,
health.
Effective
management
strategies
include
individualized
monitoring,
dietary
restriction,
supplementation,
vitamin
D
correction,
pharmacologic
interventions
targeting
renin–angiotensin–aldosterone
system
(RAAS)
activity
Additionally,
lifestyle
interventions,
including
modification,
weight
loss
strategies,
hydration
optimization,
play
key
role
preventing
complications.
Future
research
should
investigate
long-term
obesity,
emerging
therapies,
how
can
optimize
homeostasis
outcomes.
A
personalized,
multidisciplinary
approach
integrating
endocrinology,
nephrology,
clinical
nutrition
improving
prevention
obese
individuals.
Language: Английский
Does Artificial Intelligence Bring New Insights in Diagnosing Phlebological Diseases?—A Systematic Review
Biomedicines,
Journal Year:
2025,
Volume and Issue:
13(4), P. 776 - 776
Published: March 22, 2025
Background/Objectives:
Artificial
intelligence
(AI)
is
rapidly
transforming
the
landscape
of
modern
medicine,
offering
advanced
tools
for
diagnosing
complex
conditions.
In
realm
venous
pathologies
such
as
chronic
disease
(CVD),
reflux,
and
deep
thrombosis
(DVT),
AI
has
shown
tremendous
potential
to
improve
diagnostic
accuracy,
streamline
workflows,
enhance
clinical
decision-making.
This
study
aims
evaluate
efficacy
feasibility
algorithms
in
diseases
explore
their
impact
on
practice.
Methods:
paper
provides
a
comprehensive
review
key
studies
documenting
use
pathology
diagnostics,
with
different
electronic
databases
being
searched,
including
MEDLINE/Pub
Med,
Web
Science,
Scopus,
Embase,
ResearchGate,
Google
Scholar.
Results:
Out
52
reports
assessed
eligibility,
43
were
excluded
according
preset
criteria;
therefore,
findings
from
nine
major
involving
more
than
1000
patients
analyzed.
The
evaluation
shows
that
utilization
diagnosis
demonstrated
significant
improvements.
Notably,
have
achieved
an
accuracy
exceeding
90%,
significantly
reducing
inter-observer
variability
ensuring
consistent
interpretation
ultrasonographic
images
across
clinicians
settings.
Additionally,
accelerated
decreasing
time
required
image
analysis
by
50%.
Furthermore,
proven
capable
detecting
subtle
abnormalities,
minor
reflux
or
early-stage
thrombi,
which
may
be
overlooked
during
manual
evaluations.
Conclusions:
represents
transformative
innovation
management
diseases.
By
enhancing
streamlining
enabling
personalized
care,
address
current
challenges
diagnostics
patient
outcomes.
future
promising,
several
areas
development
noted,
embedding
directly
into
ultrasound
devices
provide
instantaneous
insights
evaluations;
combining
AI-processed
Doppler
data
other
imaging
modalities,
computed
tomography
MRI,
assessments;
usage
order
predict
progression
tailor
treatment
strategies
based
individual
profiles;
constructing
large-scale,
multicenter
datasets
robustness
generalizability
algorithms.
Language: Английский
The Impact of Inflammatory Markers and Obesity in Chronic Venous Disease
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2524 - 2524
Published: Nov. 4, 2024
Chronic
venous
disease
(CVD)
represents
a
significant
health
challenge,
particularly
in
obese
individuals.
This
study
focuses
on
the
interplay
between
inflammation,
obesity,
and
CVD,
by
analyzing
role
of
inflammatory
markers
progression.
Language: Английский
Bacterial Infections, Trends, and Resistance Patterns in the Time of the COVID-19 Pandemic in Romania—A Systematic Review
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1219 - 1219
Published: Dec. 14, 2024
Background:
The
COVID-19
pandemic
has
intensified
concerns
over
bacterial
infections
and
antimicrobial
resistance,
particularly
in
Romania.
This
systematic
review
explores
infection
patterns
resistance
during
the
to
address
critical
gaps
knowledge.
Methods:
A
review,
following
PRISMA
guidelines,
was
conducted
using
databases
such
as
PubMed
Scopus,
focusing
on
studies
of
from
2020
2022.
Articles
Romanian
patients
were
analyzed
for
demographic
data,
trends,
profiles.
Results:
total
87
included,
detailing
20,000
cases
infections.
found
that
Gram-negative
bacteria,
Escherichia
coli
Klebsiella
pneumoniae,
most
frequently
identified
pathogens,
alongside
Gram-positive
Staphylococcus
aureus
Enterococcus
spp.
Multidrug
(MDR)
noted
24%
reported
strains,
with
common
carbapenems
cephalosporins.
Conclusions:
amplified
complexity
managing
infections,
critically
ill
patients.
rise
MDR
bacteria
underscores
need
stringent
stewardship
control
measures.
Continuous
monitoring
trends
profiles
will
be
essential
improve
treatment
strategies
post-pandemic
healthcare
settings.
Language: Английский
The Great Saphenous Vein Proximal Part: Branches, Anatomical Variations, and Their Implications for Clinical Practice and Venous Reflux Surgery
Krisztina Munteanu,
No information about this author
Ovidiu Ghirlea,
No information about this author
Daniel Breban-Schwarzkopf
No information about this author
et al.
Journal of Cardiovascular Development and Disease,
Journal Year:
2024,
Volume and Issue:
11(8), P. 242 - 242
Published: Aug. 7, 2024
The
anatomical
variations
in
the
lower
limb
veins
play
a
critical
role
venous
reflux
surgeries.
This
study
presents
an
analysis
of
great
saphenous
vein
(GSV)
proximal
part's
peculiarities,
with
257
patients
included,
who
were
operated
for
reflux.
highlighted
progressive
increase
GSV
diameter
conjunction
complexity
variations,
ranging
from
no
tributaries
to
more
than
five
tributaries,
anterior
accessory
GSV,
or
aneurysms.
Statistical
evidenced
this
expansion
be
significantly
correlated
variations.
Additionally,
progression
chronic
disease
(CVD)
stages
was
notably
prevalent
complex
suggesting
nuanced
interplay
between
anatomy
and
CVD
severity.
Conclusively,
our
research
articulates
paramount
importance
recognizing
optimizing
surgical
outcomes
patients.
These
insights
not
only
pave
way
enhanced
diagnostic
accuracy
but
also
support
strategic
framework
within
which
interventional
treatments
are
devised,
advocating
personalized
approaches
surgery.
Language: Английский
Could cryosurgery harvested veins be used as grafts? An immunohistochemical analysis of the morphology and viability of venous samples obtained by cryostripping
Andrei Florin Parau,
No information about this author
Raluca Amalia Ceauşu,
No information about this author
Pușa Nela Gaje
No information about this author
et al.
Acta Phlebologica,
Journal Year:
2024,
Volume and Issue:
25(3)
Published: Dec. 1, 2024
Language: Английский
Salmonella Paratyphi B wound infection in a diabetic foot a rare case presentation
Atit Shah,
No information about this author
Kruthika Patel,
No information about this author
Hiral Shah
No information about this author
et al.
Indian Journal of Microbiology Research,
Journal Year:
2024,
Volume and Issue:
11(4), P. 358 - 360
Published: Dec. 9, 2024
This
case
study
presents
a
rare
instance
of
diabetic
foot
wound
infection
caused
by
Paratyphi
B
in
44-year-old
male
with
type
1
diabetes
mellitus.
Though
species
are
typically
associated
enteric
fever
and
gastrointestinal
manifestations,
some
like
can
rarely
cause
as
presented
this
case.
The
patient
underwent
antibiotic
treatment
eventually
required
surgical
amputation
the
affected
toe
due
to
infection's
chronic
nature.
underscores
importance
unusual
pathogens
infections
highlights
B's
potential
an
agent
such
cases.
Language: Английский
Physiotherapy Intervention in the Treatment of Venous Ulcers: Results from a Delphi Panel
Journal of Vascular Diseases,
Journal Year:
2024,
Volume and Issue:
3(4), P. 508 - 519
Published: Dec. 18, 2024
Background/Objectives:
Venous
ulcers
are
the
most
common
type
of
ulcerated
wounds
in
lower
limbs
and
result
from
chronic
venous
insufficiency.
The
treatment
is
multidisciplinary,
with
physiotherapy
intervention
serving
as
an
adjuvant
therapy
managing
these
wounds.
This
study
investigated
physiotherapeutic
interventions
for
management
ulcers.
Methods:
was
exploratory
descriptive
using
Delphi
method.
panel
comprised
12
experts
wound
care,
including
25.0%
physicians,
41.7%
nurses,
33.3%
physiotherapists.
Two
rounds
analysis
were
conducted.
A
quantitative
performed
to
assess
level
agreement
responses,
while
qualitative
applied
experts’
comments.
Results:
In
first
round,
consensus
varied
between
80%
100%,
second
it
ranged
83.3%
100%.
all
obtained
at
least
consensus.
included
use
compression
therapeutic
exercise:
resistance
training
(2–3
sets
10–25
repetitions,
3
times/day,
weeks),
aerobic
exercise
(at
30
min,
times/week,
stretching,
balance
training,
a
vibrating
platform.
Conclusions:
Physiotherapy
may
be
beneficial
alongside
specific
local
treatments
Therapeutic
commonly
utilized
that
could
support
overall
outcomes.
Language: Английский