Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: Feb. 24, 2023
D-allulose
is
a
high-value
rare
sugar
with
many
health
benefits.
market
demand
increased
dramatically
after
approved
as
generally
recognized
safe
(GRAS).
The
current
studies
are
predominantly
focusing
on
producing
from
either
D-glucose
or
D-fructose,
which
may
compete
foods
against
human.
corn
stalk
(CS)
one
of
the
main
agricultural
waste
biomass
in
worldwide.
Bioconversion
promising
approach
to
CS
valorization,
significance
for
both
food
safety
and
reducing
carbon
emission.
In
this
study,
we
tried
explore
non-food
based
route
by
integrating
hydrolysis
production.
Firstly
developed
an
efficient
Escherichia
coli
whole-cell
catalyst
produce
D-glucose.
Next
hydrolyzed
achieved
production
hydrolysate.
Finally
immobilized
designing
microfluidic
device.
Process
optimization
improved
titer
8.61
times,
reaching
8.78
g/L
With
method,
1
kg
was
finally
converted
48.87
g
D-allulose.
This
study
validated
feasibility
valorizing
converting
it
Molecules,
Journal Year:
2024,
Volume and Issue:
29(10), P. 2275 - 2275
Published: May 11, 2024
The
hydrolysis
and
biotransformation
of
lignocellulose,
i.e.,
biorefinery,
can
provide
human
beings
with
biofuels,
bio-based
chemicals,
materials,
is
an
important
technology
to
solve
the
fossil
energy
crisis
promote
global
sustainable
development.
Biorefinery
involves
steps
such
as
pretreatment,
saccharification,
fermentation,
researchers
have
developed
a
variety
biorefinery
strategies
optimize
process
reduce
costs
in
recent
years.
Lignocellulosic
hydrolysates
are
platforms
that
connect
saccharification
downstream
fermentation.
hydrolysate
composition
closely
related
biomass
raw
pretreatment
process,
choice
biorefining
strategies,
provides
not
only
nutrients
but
also
possible
inhibitors
for
In
this
review,
we
summarized
effects
each
stage
lignocellulosic
on
inhibitors,
analyzed
huge
differences
nutrient
retention
inhibitor
generation
among
various
emphasized
all
lignocellulose
need
be
considered
comprehensively
achieve
maximum
optimal
control
at
low
cost,
reference
development
chemicals.
Bioengineered,
Journal Year:
2022,
Volume and Issue:
13(4), P. 8135 - 8163
Published: March 17, 2022
Combating
climate
change
and
ensuring
energy
supply
to
a
rapidly
growing
global
population
has
highlighted
the
need
replace
petroleum
fuels
with
clean,
sustainable
renewable
fuels.
Biofuels
offer
solution
safeguard
security
reduced
ecological
footprint
process
economics.
Over
past
years,
lignocellulosic
biomass
become
most
preferred
raw
material
for
production
of
biofuels,
such
as
fuel,
alcohol,
biodiesel,
biohydrogen.
However,
cost-effective
conversion
lignocellulose
into
biofuels
remains
an
unsolved
challenge
at
industrial
scale.
Recently,
intensive
efforts
have
been
made
in
feedstock
microbial
engineering
address
this
problem.
By
improving
biological
pathways
leading
polysaccharide,
lignin,
lipid
biosynthesis,
limited
success
achieved,
still
needs
improve
biofuel
production.
Impressive
is
being
achieved
by
retouring
metabolic
different
hosts.
Several
robust
phenotypes,
mostly
from
bacteria
yeast
domains,
successfully
constructed
improved
substrate
spectrum,
product
yield
sturdiness
against
hydrolysate
toxins.
Cyanobacteria
also
explored
advancement
recent
however,
it
remained
underdeveloped
generate
commercialized
biofuels.
The
bacterium
Renewable and Sustainable Energy Reviews,
Journal Year:
2024,
Volume and Issue:
202, P. 114717 - 114717
Published: July 4, 2024
Butyric
acid
is
produced
from
the
petroleum
derivative
propylene
by
chemical
route.
It
an
important
precursor
in
fuel,
pharmaceutical,
chemical,
and
food
industries.
However,
due
to
demand
for
bio-based
molecules,
fermentative
production
of
butyric
renewable
feedstocks
has
received
growing
attention.
Worthy
new
applications
make
it
outstanding
precursor.
This
review
thoroughly
discusses
steps
produce
lignocellulosic
materials,
including
evaluating
suitable
biomass,
presenting
recurrent
pretreatment
fermentation
strategies,
then
discussing
factors
related
each
step's
productivity.
The
non-solventogenic
most
promising
method
producing
acid.
Currently,
bioproduction
data
are
at
laboratory
scale,
butyrate
titer
productivity
need
improvements
reach
industrial
viability.
Fermentation,
Journal Year:
2021,
Volume and Issue:
7(4), P. 248 - 248
Published: Oct. 30, 2021
Several
organic
acids
have
been
indicated
among
the
top
value
chemicals
from
biomass.
Lignocellulose
is
most
attractive
feedstocks
for
biorefining
processes
owing
to
its
high
abundance
and
low
cost.
However,
highly
complex
nature
recalcitrance
biodegradation
hinder
development
of
cost-competitive
fermentation
processes.
Here,
current
progress
in
single-pot
(i.e.,
consolidated
bioprocessing,
CBP)
lignocellulosic
biomass
will
be
examined,
based
on
potential
this
approach
dramatically
reduce
process
costs.
Different
strategies
CBP
considered
such
as:
(i)
design
microbial
consortia
consisting
(hemi)cellulolytic
valuable-compound
producing
strains;
(ii)
engineering
microorganisms
that
combine
biomass-degrading
high-value
compound-producing
properties
a
single
strain.
The
present
review
mainly
focus
production
with
application
as
building
block
(e.g.,
adipic,
cis,cis-muconic,
fumaric,
itaconic,
lactic,
malic,
succinic
acid)
since
polymer
synthesis
constitutes
largest
sector
chemical
industry.
Current
research
advances
illustrated
together
challenges
perspectives
future
investigations.
In
addition,
attention
dedicated
acid
tolerant
microorganisms,
an
essential
feature
improving
titer
productivity
fermentative
acids.
