Efficacy and role of essential oils as bio-insecticide against the pulse beetle Callosobruchus maculatus (F.) in post-harvest crops

Industrial Crops and Products, Journal Year: 2022, Volume and Issue: 189, P. 115786 - 115786

Published: Oct. 12, 2022

Language: Английский

---

Phytochemical screening and characterization of the antioxidant, anti-proliferative and antibacterial effects of different extracts of Opuntia ficus-indica peel

Journal of King Saud University - Science, Journal Year: 2022, Volume and Issue: 34(7), P. 102216 - 102216

Published: July 15, 2022

Opuntia ficus-indica peels need further investigations as they could contain multiple active molecules. Bioactive secondary metabolites are important for health maintenance and play a significant role in treating some common diseases. Hence, the present study analyzed chemical composition biological activities of plant extract using vitro models. The antioxidant assays were estimated terms DPPH radical scavenging; characterization is done total polyphenol flavonoids, well HPLC characterization. SRB assay was used anticancer analysis whereas disc diffusion minimum inhibitory concentration determined to assess antimicrobial activity. content (TPC) flavonoids (TFC) differed significantly peel cyclohexanone (OFICE), 70 % ethanol water (OFI70EE), (OFI100EE)), with varying values TPC TFC. In analysis, there observed presence 8 phenolic compounds. Antioxidant showed that OFICE has higher Bioassay based on MCF-7 O. extracts (p < 0.05) reduced cell viability cancer cells at 400 µg/mL after 72 h incubation time. Concerning antibacterial activity, gave highest inhibition compared other extracts, activity recorded against Listeria monocytogenes. Also, potential antiviral mean rates (39, 19, 67.66 %) (35, 16.66, 54.66 H5N1 rotavirus respectively. Overall, confirms antioxidant, properties studies animal models necessary validate their pharmacological applications.

Language: Английский

---

Exploring the Antibiofilm Effect of Sertraline in Synergy with Cinnamomum verum Essential Oil to Counteract Candida Species

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(9), P. 1109 - 1109

Published: Aug. 23, 2024

The emergence and spread of drug-resistant pathogens, resulting in antimicrobial resistance, continue to compromise our capability handle commonly occurring infectious diseases. rapid global multi-drug-resistant particularly systemic fungal infections, presents a significant concern, as existing drugs are becoming ineffective against them. In recent decades, there has been notable increase primarily caused by Candida species, which progressively developing resistance azoles. Moreover, species biofilms among the most common clinical settings. particular, they adhere biomedical devices, growing resilient biofilm capable withstanding extraordinarily high antifungal concentrations. years, many research programs have concentrated on development novel compounds with possible effects address this issue, new sources, such plant-derived compounds, thoroughly investigated. Essential oils (EOs), their numerous pharmacological properties, exhibit antifungal, antibacterial, antiviral activities examined at scale origin compounds. A work carried out group concerned synergistic antibacterial commercially available chemically characterized Cinnamomum verum L. essential oil (C. EO) association sertraline, selective serotonin reuptake inhibitor whose repositioning non-antibiotic drug explored over years encouraging results. aim was explore C. EO sertraline both planktonic sessile cells. Susceptibility testing synergism cells were performed using broth microdilution assay checkerboard methods. effect evident mature biofilms, reductions viability. Indeed, fractional inhibitory concentration index (FICI) lower than 0.5 for all associations, thus indicating associations strains examined. concentrations able inhibit spp. strain growth formation significantly decreased when it used combination considered, reduction percentage amount each associated component ranging from 87.5% 97%.

Language: Английский

---

A Review of Botanical Extracts with Repellent and Insecticidal Activity and Their Suitability for Managing Mosquito-Borne Disease Risk in Mexico

Pathogens, Journal Year: 2024, Volume and Issue: 13(9), P. 737 - 737

Published: Aug. 29, 2024

Among the main arboviruses affecting public health in tropical regions are dengue, zika, and chikungunya, transmitted mainly by mosquitoes of

Language: Английский

---

Antimicrobial and anticancer activities of Periplaneta americana tissue lysate: An in vitro study

Journal of King Saud University - Science, Journal Year: 2022, Volume and Issue: 34(5), P. 102095 - 102095

Published: May 18, 2022

Cancer has emerged as a life-threatening disease over the past few decades, accounting for higher rate of mortality. The advancement in cancer therapy improved quality life patients, however, chemotherapy/ radiotherapy resistance conferred by cells new threat. It demands need novel anticancer molecules from natural products. Animal product-based therapeutics are emerging drug candidates and they also highly nutritional. In this study, cyclohexane extract American cockroach, Periplaneta americana L., been evaluated its inhibitory activities against fungal bacterial human pathogens; Candida albicans MRSA effect therapeutic agent. Results showed that inhibition zones were (8, 9 mm) with minimum concentration (MIC) 62.5 µg/ml 0.9 µg/ml, both cultures, respectively. ultrastructural changes MRSA, after treatment, observed using transmission electron microscope (TEM). Cockroach extracted lysate had no cytotoxic on normal MRC-5 human-lung cell line CC50 value = 118 ± 3.4 µg/ml. However, antitumor activity an MCF-7 (breast carcinoma) IC50 values 30.2 1.62 Chemical analysis cockroach HPLC technique coupled ESI mass spectrometer proved contained high biologically active compounds. Overall, study proves potential P. agent microbial infections cells.

Language: Английский

---

The effects of wheat and yam flour diets on the toxicity of three botanical extracts to Tribolium castaneum (Herbst) and the underlying biochemical mechanisms

Heliyon, Journal Year: 2025, Volume and Issue: 11(2), P. e41959 - e41959

Published: Jan. 1, 2025

This study investigates the interactive effects of food type, exposure time, and experimental dosages on biochemical insecticidal responses Tribolium castaneum (Herbst) to toxic three botanicals. The botanicals [Piper guineense (PG), Cinnamomum verum (CV), Syzygium aromaticum (SA)] were applied individually in binary combinations (PG + SA, PG CV, SA CV). Beetles reared for two generations wheat yam flour prior insecticide exposure. specific activities α-amylase, alkaline phosphatase (AKP), acid (ACP), acetylcholinesterase (AChE), glutathione S-transferase (GST) also determined. Generally, T. each botanical extract their varied with type host used rearing beetles, dosage, time extracts. main factors (i.e. food, dosage) two-way interactions (F∗D, F∗T D∗T) significantly (p < 0.05) influenced mortality response beetles. According LD50, LD95, LT50 values, all extracts generally more beetles fed than those flour. given showed mixture CV Except which had a synergistic effect yam-reared castaneum, mixtures antagonistic beetles' rate. Irrespective higher AKP, ACP was recorded exposed alone EA combination relative control. demonstrates valuable insights needed possible development targeted sustainable strategies managing infesting

Language: Английский

---

Extraction methods of cinnamon oil

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 135 - 149

Published: Jan. 1, 2025

Language: Английский

---

Risk Assessment of Effects of Essential Oils on Honey Bees (Apis mellifera L.)

Insects, Journal Year: 2025, Volume and Issue: 16(3), P. 303 - 303

Published: March 14, 2025

The toxicity of synthetic pesticides to non-target organisms has prompted a shift towards more environmentally friendly agricultural pest control methods, including the use essential oils as possible biopesticides. Before these natural chemicals can be widely adopted for protecting food supplies and human health, it is crucial evaluate their impacts on pollinators, such honey bees. In this study, we examined effects one commercially available oil mixture (EcoTec+) four components (β-bisabolene, cinnamaldehyde, 1,8-cineole, eugenol) bee workers using feeding or spray treatment. We then assessed responses esterase (EST), glutathione-S-transferase (GST), acetylcholine (AChE), P450. EcoTec+ increased P450 transcript, while bisabolene inhibited EST AChE, GST, caused mixed response without being lethal. Cinnamaldehyde exhibited when ingested, suppressing eliciting in AChE. Cineole but response. Eugenol suppressed AChE was toxic contact. also assayed combinations each compound with formulations representative major pesticide categories, though no significant interactions were found. Overall, tested did not cause acute lethal bees; however, biochemical varied, mostly remaining sublethal. These findings suggest that could considered safe around

Language: Английский

---

Essential oils from the leaves of Laurel plants Cinnamomum javanicum Blume and Cryptocarya maclurei Merr: Chemical analysis and biological activities

Journal of Essential Oil Bearing Plants, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: April 22, 2025

Language: Английский

---

Synergistic Action of Cinnamomum verum Essential Oil with Sertraline

Antibiotics, Journal Year: 2022, Volume and Issue: 11(11), P. 1617 - 1617

Published: Nov. 13, 2022

Cinnamomum verum L. essential oil (CEO), commonly known as Ceylon cinnamon or tree, is regarded one of the most employed oils in field aromatherapy. It usually applied externally astringent, antipruritic, rubefacient, and anti-septic agent. Furthermore, both vitro vivo research have demonstrated its numerous pharmacological effects, including potentiality for treating neuralgia, myalgia, headache, migraine. Several pieces also corroborated significant antiviral antimicrobial properties. Cinnamaldehyde, eugenol, caryophyllene, cinnamyl acetate, cinnamic acid are representative compounds that generally found greater quantities CEO play a pivotal role determining activities. Due to global antibiotic resistance scenario dwindling amount funding dedicated developing new antibiotics, recent years has concentrated on exploring specific economic approaches against microbial infections. In this context, purpose study was investigation synergistic antibacterial activities commercially available chemically characterized combination with sertraline, selective serotonin reuptake inhibitor (SSRI), whose repositioning non-antibiotic drug been explored over encouraging results. effects titled were assessed toward wide panel Gram-positive Gram-negative bacteria. The efficacy investigated by using checkerboard microdilution method. interesting preliminary results obtained suggested effect (fractional inhibitory index, FICI < 0.5) sertraline CEO, leading severe growth inhibition all bacterial species under investigation.

Language: Английский

---