Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: April 5, 2023
Obesity
and
type
2
diabetes
(T2D)
are
chronic
conditions
with
detrimental
impacts
on
the
overall
health
of
individuals.
Presently,
use
pharmacological
agents
in
obesity
T2D
offers
limited
benefits
pose
side
effects.
This
warrant
studies
remedies
that
less
toxic
inexpensive
while
effective
ameliorating
secondary
complications
T2D.
Plant-based
have
been
explored
increasingly
due
to
their
remarkable
properties
safety
profile.
We
searched
for
pre-clinical
evidence
published
from
inception
until
2023
PubMed,
Scopus,
Google,
Semantic
scholar
Corchorus
olitorius
(
C.
)
both
Our
focus
was
understand
beneficial
impact
this
plant-based
remedy
basic
glycemic,
lipid,
inflammatory,
biomarkers
oxidative
stress.
The
gathered
review
suggests
treatment
may
significantly
reduce
blood
glucose,
body
weight,
total
cholesterol,
triglycerides,
low-density
lipoprotein
(LDL)
concomitant
increasing
high-density
lipoprotein-cholesterol
(HDL-c)
rodent
models
Interestingly,
effect
consistent
reduction
malonaldehyde,
superoxide
dismutase
catalases,
tumor
necrosis
factor-alpha,
interleukins,
leptin.
Some
mechanisms
by
which
reduces
glucose
levels
is
through
stimulation
insulin
secretion,
β-cell
proliferation,
thus
promoting
sensitivity;
process
mediated
ascorbic
acid
present
plant.
anti-hyperlipidemia
attributable
content
ferulic
found
plant,
inhibits
3-Hydroxy-3-methyl
glutaryl
coenzyme
A
(HMG-CoA)
reductase
inhibitors
results
reduced
synthesis
cholesterol
increased
hepatic
LDL-c
receptor
expression,
respectively.
provides
extensive
knowledge
further
highlights
potential
metabolic
parameters,
lipid
profile,
inflammation,
stress
Ultrasonics Sonochemistry,
Journal Year:
2024,
Volume and Issue:
106, P. 106877 - 106877
Published: April 16, 2024
Lycopene-rich
guava
(Psidium
guajava
L.)
exhibits
significant
economic
potential
as
a
functional
food
ingredient,
making
it
highly
valuable
for
the
pharmaceutical
and
agro-food
industries.
However,
there
is
need
to
enhance
extraction
methods
of
lycopene
fully
exploit
its
beneficial
uses.
In
this
study,
we
evaluated
various
ionic
liquids
identify
most
effective
one
extracting
from
guava.
Among
thirteen
with
varying
carbon
chains
or
anions,
1-butyl-3-methylimidazolium
chloride
demonstrated
highest
productivity.
Subsequently,
single-factor
experiment
was
employed
test
impact
several
parameters
on
efficiency
using
selected
liquid.
These
included
time,
ultrasonic
power,
liquid-solid
ratio,
concentration
liquid,
well
material
particle
size.
Moreover,
models
artificial
neural
networks
genetic
algorithms
(ANN-GA)
response
surface
methodology
(RSM)
were
comprehensively
assess
first
four
key
parameters.
The
optimized
conditions
liquid
ultrasound-assisted
(IL-UAE)
determined
follows:
33
min
225
W
22
mL/g
3.0
mol/L
IL
concentration,
cycles
three.
Under
these
conditions,
production
reached
an
impressive
yield
9.35
±
0.36
mg/g
while
offering
advantages
such
high
efficiency,
time
savings,
preservation
benefits,
importantly
environmental
friendliness.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
11
Published: Jan. 5, 2024
This
systematic
review
with
meta-analysis
evaluated
the
antioxidant
effect
of
lycopene
as
an
adjuvant
treatment
for
periodontal
disease.
PubMed,
EMBASE
and
Web
Science
databases
were
consulted.
According
to
PICOs
strategy,
inclusion
criteria
established
intervention
studies
Randomized
Controlled
Trials
in
Probing
depth
subjects
(participants)
treated
conventional
(intervention)
compared
patients
(control)
which
response
(outcome)
was
assessed.
The
risk
bias
randomized
assessed
using
Cochrane
Risk
Bias
Tool.
methodological
quality
included
measured
Jadad
scale.
Quantitative
data
analyzed
six
random-effects
meta-analyses,
taking
into
account
parameters:
Pocket
Depth,
Clinical
Attachment
Loss,
Bleeding
on
Probing,
Plaque
Index,
Uric
Acid
Gingival
Index.
Six
further
meta-analyses
performed,
according
follow-up
(short-,
medium-
long-term).
Of
339
identified,
only
7
met
eligibility
criteria.
parameters
obtained
statistical
significance
assessment
plaque
index
(
Lycopene
is
a
compound
of
colored
origin
that
shows
strong
antioxidant
activity.
The
ability
to
neutralize
free
radicals
by
lycopene
the
basis
its
pro-health
effect,
including
inhibit
development
many
civilization
diseases.
Therefore,
this
study
focuses
on
importance
effect
in
inhibiting
such
diseases
as
cardiovascular
diseases,
etiology
etiology,
within
nervous
system.
Foods,
Journal Year:
2023,
Volume and Issue:
12(16), P. 3121 - 3121
Published: Aug. 20, 2023
In
recent
years,
there
has
been
increasing
concern
about
the
safety
of
additives
used
to
extend
shelf-life
food
products.
As
a
result,
lycopene,
natural
phytochemical
compound,
attracted
attention,
as
it
demonstrated
be
potential
alternative
traditional
artificial
antioxidants,
with
significant
health
benefits
when
applied
preservation.
Based
on
this,
this
review
introduces
specific
forms
lycopene
currently
an
antioxidant
in
foods,
both
its
naturally
occurring
fruits
and
vegetables
artificially
added
involving
technologies
such
composite
coating,
active
film
packaging,
emulsion,
microcapsules.
addition,
also
provides
comprehensive
summary
effects
progress
preservation
different
types
products,
meat,
seafood,
oil,
dairy
fruits,
vegetables,
last
decade.
At
last,
points
out
limitations
including
insolubility
water,
dark
color,
high
sensitivity
heat
or
light,
well
solutions
load
suitable
carriers,
combining
antimicrobial
substances
other
actives,
order
broaden
applications
future
foods.
Food & Function,
Journal Year:
2023,
Volume and Issue:
14(11), P. 5090 - 5104
Published: Jan. 1, 2023
In
diabetic
islets,
the
infiltration
of
macrophages
into
intra-islets
triggers
islet
β
cells
dysfunction.
Lycopene
may
preserve
M1/M2
macrophage
homeostasis
to
improve
function
via
TLR4/MyD88/NF-κB
signaling
pathway.
Frontiers in Nutrition,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 5, 2025
Nutritional
interventions
facilitating
the
consumption
of
natural,
affordable,
and
environment-compatible
health-promoting
functional
foods
are
a
promising
strategy
for
controlling
non-communicable
diseases.
Given
that
complex
tomato
micronutrients
produces
healthier
outcomes
than
lycopene,
its
major
antioxidant
component,
new
strategies
to
improve
health-supporting
properties
berry
ongoing.
In
this
context,
whole
food
supplement
(WTFS),
enriched
by
2%
olive
wastewater
containing
healthy
nutrients
with
converging
biologic
activities,
has
recently
been
developed,
which
is
superior
those
present
in
commodities
or
obtained
conventional
processing
methods.
WTFS
equals
activity
N-acetyl-cysteine
interferes
multiple
inflammation
cellular
transformation-sustaining
metabolic
pathways.
interventional
studies,
inhibits
prostate
experimental
tumors
improves
benign
hypertrophy-associated
symptoms
no
associated
side-effects.
Although
may
be
susceptible
further
improvements
clinical
scrutiny,
composition
embodies
features
advanced
ease
adherence
dietary
patterns,
is,
Mediterranean
diet,
aimed
at
contrasting
mitigating
low-grade
inflammation,
thus
being
interceptive
preventive
