Optimization of Ultrasound-Assisted Extraction of Chlorogenic Acid from Potato Sprout Waste and Enhancement of the In Vitro Total Antioxidant Capacity DOI Creative Commons

Luciano Mangiapelo,

Francesca Blasi, Federica Ianni

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(2), P. 348 - 348

Published: Feb. 1, 2023

Potato sprouts, an underutilized by-product of potato processing, could be exploited for the recovery caffeoyl-quinic acids (CQAs), a family polyphenols with well-recognized biological activities. In this work, predominant compound class, 5-CQA, was extracted by Ultrasound-Assisted Extraction (UAE) under conditions optimized Experimental Design. The investigated variables solid/solvent ratio (1:10–1:50 g/mL), water content in ethanol (30–100% v/v) and UAE time (5–20 min) highlighted critical influence last two factors on extraction efficiency: extracts richer 5-CQA were obtained lower (30%) (5 min). addition ascorbic acid (1.7 mM) as anti-browning agent to solvent improved efficiency compared acetic citric (3158.71 μg/mL, 1766.71 1468.20 respectively). A parallel trend three increase use freeze-dried sprouts (4980.05 4795.62, 4211.25 Total antioxidant capacity (TAC) vitro demonstrated being more valuable technique than conventional maceration. Furthermore, three-times-higher values TPC (7.89 mg GAE/g) TAC (FRAP: 24.01 TE/g; DPPH: 26.20 ABTS 26.72 TE/g) measured extract initial one. An HPLC-DAD method applied monitor recovery, while LC-HRMS/MS investigation allowed us perform analyte identity confirmation along detection glycoalkaloids α-solanine α-chaconine. This evidence underlines necessity develop purification strategies order maximize potential sprout waste source 5-CQA.

Language: Английский

The Potential of Spent Coffee Grounds in Functional Food Development DOI Open Access

Elza Bevilacqua,

Vinícius Fernandes Cruzat, Indu Singh

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(4), P. 994 - 994

Published: Feb. 16, 2023

Coffee is a popular and widely consumed beverage worldwide, with epidemiological studies showing reduced risk of cardiovascular disease, cancers non-alcoholic fatty liver disease. However, few have investigated the health effects post-brewing coffee product, spent grounds (SCG), from either hot- or cold-brew coffee. SCG hot-brew improved metabolic parameters in rats diet-induced syndrome gut microbiome these humans; further, energy consumption humans. contains similar bioactive compounds as including caffeine, chlorogenic acids, trigonelline, polyphenols melanoidins, established benefits safety for human consumption. Further, utilisation could reduce estimated 6-8 million tonnes waste each year worldwide production beverage. In this article, we explore major by-product consumption, together potential economic impacts non-health applications SCG. The known present show cancer, disease disorders. Based on SCG, it expected that foods may moderate chronic while reducing environmental impact otherwise dumped landfill.

Language: Английский

Citations

44
Proximate composition and health benefit of Roselle leaf (Hibiscus sabdariffa). Insight on food and health benefits DOI Creative Commons
Great Iruoghene Edo, Princess Oghenekeno Samuel, Agatha Ngukuran Jikah

et al.

Food Chemistry Advances, Journal Year: 2023, Volume and Issue: 3, P. 100437 - 100437

Published: Sept. 11, 2023

Zobo leaves, also known as Roselle leaves are of the Malvaceae plant Hibiscus sabdariffa, they a common culinary ingredient well traditional medicine in many countries including their role treating various ailments and promoting overall health. The biological properties this have been studied found to be benefit general improvement health such anti-inflammatory, anti-diabetic, anti-hypertensive, anti-cancer effects, potency against respiratory infections, skin diseases, gastrointestinal disorders etcetera. These all stem from bioactive components (anthocyanins, polyphenols, flavonoids, protocatechuic acid, malic ascorbic hibiscus acid contained it. Our review focuses on these sabdariffa compounds that responsible for them. nature, proximate composition nutrient mineral content, physicochemical uses according different cultures included our work. Finally, importance further research fully understand pharmacology potential therapeutic applications leaf its highlighted.

Language: Английский

Citations

42
Spent coffee grounds: Present and future of environmentally friendly applications on industries-A review DOI
Nan Zhao, Zhongyang Liu, Ting Yu

et al.

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 143, P. 104312 - 104312

Published: Dec. 24, 2023

Language: Английский

Citations

41
Bioactive compounds in coffee and their role in lowering the risk of major public health consequences: A review DOI Creative Commons
Markos Makiso Urugo, Yetenayet B. Tola, Onwuchekwa Ogah

et al.

Food Science & Nutrition, Journal Year: 2023, Volume and Issue: 12(2), P. 734 - 764

Published: Nov. 22, 2023

This article addresses the bioactive components in coffee aroma, their metabolism, and mechanism of action lowering risk various potential health problems. The main involved perceived aroma its related benefits are caffeine, chlorogenic acid (CGA), trigonelline, diterpenes, melanoids. These compounds physiological activities. Caffeine has been shown to have anticancer properties, as well ability prevent onset progression hepatocellular carcinoma be anti-inflammatory. CGA exhibits antioxidant is implicated gut health, neurodegenerative disease protection, type 2 diabetes, cardiovascular prevention. Furthermore, together with linked activity. Trigonelline, on other side, found lower oxidative stress by increasing enzyme activity scavenging reactive oxygen species. It also prevents formation kidney stones. Diterpenes melanoids possess anti-inflammatory respectively. Consuming three four cups filtered per day, depending an individual's condition status, a several degenerative diseases. Despite benefits, excessive intake above recommended daily dosage, calcium vitamin D deficiency, unfiltered consumption all increase concerns. In conclusion, moderate lowers different noncommunicable

Language: Английский

Citations

31
Advanced sample preparation and chromatographic techniques for analyzing plant-based bioactive chemicals in nutraceuticals DOI Creative Commons
Muhammed Mesud HÜRKUL, Ahmet Çetinkaya, Seyda Yayla

et al.

Journal of Chromatography Open, Journal Year: 2024, Volume and Issue: 5, P. 100131 - 100131

Published: April 15, 2024

Since ancient times, humanity has used plants to cure diseases or maintain health. Nowadays, obtaining the bioactive components of and researching their effects continues at great speed. Plant-derived chemicals are studied with interest in food, pharmaceutical cosmetic industries. The complexity city life limits access natural habitat. Nutraceuticals indispensable products our age protect Many methods have been developed successfully applied for extracting crude plant extracts pure active substances included nutraceuticals from tissues quantitative analysis. This study compiled ingredients techniques analyzing compounds. extraction plant-based (maceration, Soxhlet extraction, decoction, infusion, hydro distillation, ultrasound-assisted (UAE), microwave-assisted (MAE), enzyme-assisted (EAE), pressurized liquid (PLE), supercritical fluid (SFE)) were explained detail, some important source summarized table form. Additionally, studies using different analytical such as high-performance chromatography (HPLC), gas (GC), thin layer (TLC), mass spectrometry (MS), ultra-performance (UPLC) discussed. Finally, evaluating its effectiveness compounds prospects more environmentally friendly alternative traditional solvents emphasized. review covers latest practices new trends over last three years.

Language: Английский

Citations

14
A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention DOI
Tao Zhang, Yanjuan Huang,

Yujun Gong

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 184, P. 98 - 113

Published: June 22, 2024

Language: Английский

Citations

12
Chlorogenic acid-assisted dopamine‑sodium alginate composite nanofiber membranes for promoting wound healing DOI
Meng Zhang, Yang Wang,

Xueling Yin

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 354, P. 123298 - 123298

Published: Jan. 23, 2025

Language: Английский

Citations

2
Extraction of chlorogenic acid from Lonicera japonica Thunb. using deep eutectic solvents: Process optimization and mechanism exploration by the combination of experiment and molecular simulation DOI
Zhenyan Fan, Jingyu Li,

Junyu Zhou

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113280 - 113280

Published: March 1, 2025

Language: Английский

Citations

2
A Comparative Study for Nutritional and Phytochemical Profiling of Coffea arabica (C. arabica) from Different Origins and Their Antioxidant Potential and Molecular Docking DOI Creative Commons
Akhtar Ali, Hafza Fasiha Zahid, Jeremy J. Cottrell

et al.

Molecules, Journal Year: 2022, Volume and Issue: 27(16), P. 5126 - 5126

Published: Aug. 11, 2022

Coffee is the most widely used beverage globally and contains many bioactive compounds, including phenolic alkaloids, triterpenes, organic acids, amino hormones, fatty acids. The main objective of this study was comparative profiling Australian, Colombian, Ethiopian, Peruvian C. arabica using LC-ESI-QTOF-MS/MS. In study, we tentatively identified 136 metabolites, five (05) six (06) three (03) acids (l-phenylalanine, l-tyrosine, l-pyroglutamic acid), two (02) hormones (melatonin serotonin), one (01) furopyrans (goniothalenol), carotenoid (crocetin), terpenoids, thirty-eight (38) forty-one (41) flavonoids, stilbenes, lignans twenty-three (23) other polyphenols in arabica. highest TPC value (17.74 ± 0.32 mg GAE/g) measured Colombian coffee while lowest (10.24 0.73 coffee. has a higher antioxidant potential than studied samples. A total nineteen metabolites were mapped through LC-MS/MS. Quinic acid derivatives quantified concentrations metabolites. Furthermore, molecular docking predicted that chlorogenic compound contributes to anti-Alzheimer anti-diabetic activities obtained results indicate vast number compounds which have health benefits. research could be conducted validate effect these on flavor profile beverages.

Language: Английский

Citations

39
Discrimination of Green Coffee (Coffea arabica and Coffea canephora) of Different Geographical Origin Based on Antioxidant Activity, High-Throughput Metabolomics, and DNA RFLP Fingerprinting DOI Creative Commons
Giuseppe Mannino,

Ronja Kunz,

Massimo E. Maffei

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(5), P. 1135 - 1135

Published: May 21, 2023

The genus Coffea is known for the two species C. arabica (CA) and canephora (CC), which are used to prepare beverage coffee. Proper identification of green beans coffee varieties based on phenotypic phytochemical/molecular characteristics. In this work, a combination chemical (UV/Vis, HPLC-DAD-MS/MS, GC-MS, GC-FID) molecular (PCR-RFLP) fingerprinting was discriminate commercial accessions from different geographical origin. highest content polyphenols flavonoids always found in CC accessions, whereas CA showed lower values. ABTS FRAP assays significant correlation between phenolic antioxidant activity most accessions. We identified 32 compounds, including 28 four N-containing compounds. contents caffeine melatonin were detected levels quercetin kaempferol derivatives Fatty acids characterized by low linoleic cis octadecenoic acid high amounts elaidic myristic acid. Discrimination according their origin achieved using high-throughput data analysis, combining all measured parameters. Lastly, PCR-RFLP analysis instrumental recognition markers majority Using restriction enzyme AluI trnL-trnF region, we clearly discriminated arabica, cleavage performed enzymes MseI XholI 5S-rRNA-NTS region produced specific discrimination patterns useful correct This work extends our previous studies provides new information complete flavonoid profile, with DNA assess

Language: Английский

Citations

21