Green synthesis of silver nanoparticles by root extract of Premna integrifolia L. and evaluation of its cytotoxic and antibacterial activity

Materials Chemistry and Physics, Journal Year: 2023, Volume and Issue: 297, P. 127413 - 127413

Published: Jan. 21, 2023

Language: Английский

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Nanomaterials-Based Wound Dressing for Advanced Management of Infected Wound

Antibiotics, Journal Year: 2023, Volume and Issue: 12(2), P. 351 - 351

Published: Feb. 8, 2023

The effective prevention and treatment of bacterial infections is imperative to wound repair the improvement patient outcomes. In recent years, nanomaterials have been extensively applied in infection control healing due their special physiochemical biological properties. Incorporating antibacterial into dressing has associated with improved biosafety enhanced outcomes compared naked nanomaterials. this review, we discuss progress application nanomaterial-based dressings for advanced management infected wounds. Focus given therapy as well all-in-one detection infections. Notably, highlight use nanoparticles intrinsic performances, such metals metal oxide that are capable killing bacteria reducing drug-resistance through multiple antimicrobial mechanisms. addition, proven be ideal drug carriers delivery release antimicrobials either passive or stimuli-responsive manners. ability kill based on photo-triggered heat (photothermal therapy) ROS (photodynamic therapy), unparalleled advantages control. Moreover, examples intelligent can detect in-situ while providing timely Finally, challenges current provide further perspectives future healing.

Language: Английский

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Theranostic magnetic nanoparticles: Synthesis, properties, toxicity, and emerging trends for biomedical applications

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 81, P. 104295 - 104295

Published: Feb. 21, 2023

Language: Английский

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Advances in solid-phase extraction techniques: Role of nanosorbents for the enrichment of antibiotics for analytical quantification

Journal of Chromatography A, Journal Year: 2023, Volume and Issue: 1695, P. 463937 - 463937

Published: March 21, 2023

Language: Английский

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Second Near‐Infrared Plasmonic Nanomaterials for Photoacoustic Imaging and Photothermal Therapy

Small, Journal Year: 2023, Volume and Issue: 19(30)

Published: April 14, 2023

Abstract Photoacoustic imaging (PAI) and imaging‐guided photothermal therapy (PTT) in the second near‐infrared window (NIR‐II, 1000–1700 nm) have received increasing attention owing to their advantages of greater penetration depth higher signal‐to‐noise ratio. Plasmonic nanomaterials with tunable optical properties strong light absorption provide an alternative dye molecules, showing great prospects for phototheranostic applications. In this review, research progress principally modulating plasmonic nanomaterials, especially affecting parameters such as size, morphology, surface chemical modification, is introduced. The commonly used NIR‐II window, including noble metals, semiconductors, heterostructures, are then summarized. addition, biomedical applications these PAI PTT phototheranostics highlighted. Finally, perspectives challenges advancing practical use clinical translation discussed.

Language: Английский

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Noble metal nanoparticles and graphene oxide based hybrid nanostructures for antibacterial applications: Recent advances, synergistic antibacterial activities, and mechanistic approaches

Micro and Nano Engineering, Journal Year: 2024, Volume and Issue: 22, P. 100239 - 100239

Published: Feb. 5, 2024

Antibiotic resistance is a critical and expanding problem for public health, as well significant challenge the pharmaceutical medical industries. Pathogenic bacteria that are resistant to antibiotics developing at rate far faster than new drug development. Therefore, there an urgent need novel class of with distinct mode action better effect. In this context, noble metal nanoparticles (NPs) (i.e. Ag, Au, Cu) graphene oxide (GO) based nanocomposite materials have emerged nanohybrid owing their characteristics which combine provide excellent antibacterial effects. These nanohybrids been engineered extensively investigated in recent years diverse range applications including applications. This short review envisages advances carried out understanding various activities NPs-GO emphasis on engineering nanostructures synergetic mechanisms actions. The mechanism has discussed, emphasizing role GO NPs towards combined activities. Furthermore, latest developments such promising GO-noble NPs-based discussed followed by outlook future prospects.

Language: Английский

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Metal nanoparticle hybrid hydrogels: the state-of-the-art of combining hard and soft materials to promote wound healing

Theranostics, Journal Year: 2024, Volume and Issue: 14(4), P. 1534 - 1560

Published: Jan. 1, 2024

Wounds represent a grave affliction that profoundly impacts human well-being.Establishing barriers, preventing infections, and providing conducive microenvironment constitute the crux of wound therapy.Hydrogel, polymer with an intricate three-dimensional lattice, serves as potent tool in erecting physical barriers nurturing environment to healing.This enables effective control over exudation, hemostasis, accelerated closure, diminished scar formation.As result, hydrogels have gained extensive traction realm treatment.Metallic nanoparticle carriers, characterized by their multifaceted responses encompassing acoustics, optics, electronics, demonstrated efficacy management.Nevertheless, these carriers encounter challenges associated swift clearance nonuniform effectiveness.The hybridization metallic overcomes shortcomings inherent nanoparticle-based therapy.This amalgamation not only addresses limitations but also augments mechanical robustness hydrogels.It confers upon them attributes such environmental responsiveness multifunctionality, thereby synergizing strengths compensating for weaknesses.This integration culminates precise intelligent management wounds.This review encapsulates structural classifications, design strategies, therapeutic applications, underlying mechanisms metal hybrid context acute chronic treatment.The discourse delves into generation novel or enhanced arising from how current paradigm therapy leverages attributes.Amidst this continually evolving frontier, potential revolutionize treatment is underscored.

Language: Английский

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Nanomaterials in the Wound Healing Process: New Insights and Advancements

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(3), P. 300 - 300

Published: Feb. 21, 2024

Wounds, which are becoming more common as a result of traumas, surgery, burns, and chronic illnesses like diabetes, remain critical medical problem. Infectious bacteria impact the healing process, particularly if its biofilm (biological films) leads to prolonged effect. Nanomaterials have emerged promising candidates in field wound due their unique properties versatile applications. New insights into interactions between nanomaterials microenvironments shed light on mechanisms underlying therapeutic effects. However, significantly minimal amount research has been carried out see these promote process. In this review, we provided an outline various types that studied for wounds infection prevention. Overall, utilization holds great promise continues evolve, providing new opportunities development effective efficient care therapies.

Language: Английский

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Laser ablated Au@Ag@Au core double shelled as inorganic nanocomposite for control growth of liver cancer cells (Hep-G2): 2D tissue culture model and insilico assessment

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 113841 - 113841

Published: Jan. 1, 2025

Language: Английский

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Herbal Theranostics: Controlled, Targeted Delivery and Imaging of Herbal Molecules

Nanotheranostics, Journal Year: 2024, Volume and Issue: 8(3), P. 344 - 379

Published: Jan. 1, 2024

Modern medicine relies on a small number of key biologics, which can be found in nature but require further characterization and purification before they used.Since the herbal remedy is given through dated ineffective method drug administration, its effectiveness diminished.The novel form delivery has potential to increase substances while decreasing their side effects.This main idea behind utilising different ways treatments.Several benefits arise from formulations compounds as compared conventional counterparts.These include enhanced penetrating ability into tissues, constant effective doses, resistance physical chemical degradation.Controlled targeted that components allow for more traditional dosing simultaneously increasing efficacy.Enhancing biodistribution target site accumulation systemically administered medicines goal nanomedicine formulations.The field nanotheranostics made significant advancements development by combining diagnostic therapeutic functions single nanoscale platform.It critically important create theranostic nanoplatform derived plants intrinsically "all-in-one" molecules.In addition examining mechanistic approach nanoparticle synthesis, this review highlights effects phytochemical systems.Furthermore, we have evaluated scope future field, discussed several nanoparticles been developed recently imaging, provided experimental evidence supports usage.

Language: Английский

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