HPLC-ESI-QTOF-MS/MS Analysis of Artemisia cina Leaves Aqueous Extract and Flavonoid Isolation Using High-speed Countercurrent Chromatography DOI Creative Commons
Sonwabiso Tshunungwa, Bashaer Alsharif, Tolkyn Bekezhanova

et al.

Acta Poloniae Pharmaceutica - Drug Research, Journal Year: 2024, Volume and Issue: 81(2), P. 319 - 330

Published: June 6, 2024

Artemisia cina Berg ex Poljakov, a shrubby plant endemic to the semi-arid areas of Kazakhstan, has as long history being used in traditional medicines an antitumour, antifungal and anthelmintic agent. In preliminary study carried out on different methodologies produce aqueous extracts A. it was seen that simple extract (as infusion plant) had strongest anti-SARS-CoV-2 activity. The profiling this performed using Liquid Chromatography-Electrospray Ionization-Quadrupole-Time-of-Flight Mass Spectrometry (LC-ESI-Q-TOF-MS) while High-Speed Countercurrent Chromatography (HSCCC) Sephadex LH-20 column were utilised isolate purify ethyl acetate obtained from extract. Nuclear Magnetic Resonance (NMR) for structural elucidation. flavonoid spinacetin-7-O-glucoside found be one main compounds present With emergence COVID-19 pandemic frequency which new COVID strains occur, demand drugs with activity is at all-time high. Flavonoids artemisinin identified by LC-MS are hypothesised key behind extract, however needs further tested explored.

Language: Английский

Sucrose-dependent production of biomass and bioactive compounds in adventitious root cultures of Glycyrrhiza glabra L., an endangered medicinal plant DOI

Fereshteh Maskani,

Mansour Gholami, Hassan Sarikhani

et al.

Biocatalysis and Agricultural Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 103518 - 103518

Published: Feb. 1, 2025

Language: Английский

Citations

0
Prediction of the potential distribution area of Glycyrrhiza inflata in China using a MaxEnt model DOI Creative Commons

Zhenzhu Du,

Wenbin Xu, Yuxia Wang

et al.

Frontiers in Ecology and Evolution, Journal Year: 2024, Volume and Issue: 12

Published: April 8, 2024

Glycyrrhiza inflata Batalin is an important medical plant of the genus . It one key protected plants in China, distributed desert areas southern Xinjiang and Dunhuang Gansu Province. has a strong resistance to drought, heat, salt stresses, plays pivotal role sand fixtion areas. In this study, based on 157 valid distribution records eight environmental factors including climate altitude, potential area G. last glacial maximum, middle Holocen, modern, future (2050) times China were predicted, using optimized MaxEnt model ArcGis 10.2 software. The results showed that predicted was highly consistent with current range, under receiver operating characteristic (AUC) curve 0.986, indicating prediction performance excellent. climatic affecting precipitation December average annual precipitation. Meanwhile, suitable modern 1,831,026 km 2 , mainly Turpan-Hami Basin, Tarim Province, Lop Nur Town as center. 2050, for will be 1,808,090 250,970 which suitable, 150,600 smaller than times, reduction rate 60.0%. Therefore, there trend great From glaciation maximum Holocene, geographical center shifted southwest margin Kumtag Desert, Xinjiang, then later continued shift southwest. This study provide basis understanding origin evolution developing conservation strategies minimize impacts environment change, utilizing resource.

Language: Английский

Citations

1
HPLC-ESI-QTOF-MS/MS Analysis of Artemisia cina Leaves Aqueous Extract and Flavonoid Isolation Using High-speed Countercurrent Chromatography DOI Creative Commons
Sonwabiso Tshunungwa, Bashaer Alsharif, Tolkyn Bekezhanova

et al.

Acta Poloniae Pharmaceutica - Drug Research, Journal Year: 2024, Volume and Issue: 81(2), P. 319 - 330

Published: June 6, 2024

Artemisia cina Berg ex Poljakov, a shrubby plant endemic to the semi-arid areas of Kazakhstan, has as long history being used in traditional medicines an antitumour, antifungal and anthelmintic agent. In preliminary study carried out on different methodologies produce aqueous extracts A. it was seen that simple extract (as infusion plant) had strongest anti-SARS-CoV-2 activity. The profiling this performed using Liquid Chromatography-Electrospray Ionization-Quadrupole-Time-of-Flight Mass Spectrometry (LC-ESI-Q-TOF-MS) while High-Speed Countercurrent Chromatography (HSCCC) Sephadex LH-20 column were utilised isolate purify ethyl acetate obtained from extract. Nuclear Magnetic Resonance (NMR) for structural elucidation. flavonoid spinacetin-7-O-glucoside found be one main compounds present With emergence COVID-19 pandemic frequency which new COVID strains occur, demand drugs with activity is at all-time high. Flavonoids artemisinin identified by LC-MS are hypothesised key behind extract, however needs further tested explored.

Language: Английский

Citations

0