Published: May 1, 2023
Magneto-mechanical actuation induces the most destruction on cancer cells when employed magnetic nanomaterials with shape anisotropy as well high values of saturation magnetization. The aim this study is to compare effects nanoparticles and nanowires human osteosarcoma cells. In paper we present results obtained using Fe-(Cr/Ti/Mn)-Nb-B Ni-Fe Co-Fe for cell magneto-mechanical actuation.
Language: Английский
Environmental Technology & Innovation, Journal Year: 2024, Volume and Issue: 35, P. 103688 - 103688
Published: May 22, 2024
Handling nuclear metallic waste is a crucial issue for the industry, notably by using adapted decontamination processes. Colloidal gels can be applied spraying of large and plane surfaces, such as walls or floors. However, this implementation mode limits their use inaccessible complex geometries surfaces. For that purpose, magnetic have been formulated incorporating magnetite particles in pre-synthesized colloidal gel able to decontaminate stainless steel. Such thus attracted magnet, allowing remote application surfaces with limited access. The presence does not influence inherent properties gel, but plays significant role on spreading increasing viscosity. Then, linear relationship between thickness possibilities has highlighted. Furthermore, dissolve time, properties, consequently are modified. Finally, formulation compromise found long-term storage gels, while maintaining efficiency.
Language: Английский
Citations
1
IEEE Sensors, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 4
Published: Oct. 29, 2023
Measuring the magnetic susceptibility of fluids is an expensive and challenging task. Thus, this paper presents a simple low-cost technique based on one solenoid. The coil plunged into ferrofluid. By knowing system response from simulation, can be derived by measuring coil's inductance. In paper, was assessed, measured in range 0.005 to 0.054 for six particle concentrations 1 14 mg Fe per ml. obtained results were also validated with reference using vibrating sample magnetometer.
Language: Английский
Citations
3
Published: Jan. 1, 2023
Magnetorheological fluid (MRF) is a material that changes its viscosity in response to magnetic field. However, one of the challenges with MRF particles (MPs) used often settle out suspension, reducing their effectiveness. To improve suspension stability and rheological properties some extent, this paper proposes preparation Fe3O4 hollow spheres using simple, one-step synthetic solvothermal method. The surface morphology, particle size distribution, crystal structure are characterized. results show shell thickness forms about 100 nm saturation magnetization intensity 86.33 emu/g at ratio FeCl3·6H2O CO(NH2)2 substance 1:10 when porosity agent urea 0.06 mol. Furthermore, was prepared dimethyl silicone oil as base carrier fluid., were investigated by varying content spheres. While increasing mass fraction spheres, shear yield stress increase. based on significantly improves fluid, making them more suitable for practical applications.
Language: Английский
Citations
2
Nanomaterials, Journal Year: 2023, Volume and Issue: 13(22), P. 2941 - 2941
Published: Nov. 14, 2023
Magnetic nanoparticles (MPs) are emerging as powerful and versatile tools for biotechnology, including cancer research theranostic applications. Stem cell-mediated magnetic particle delivery has been previously recognized a modality to target sites of malignancies. Here, we propose the use adipose-derived mesenchymal cells (ADSC) targeted Fe-Cr-Nb-B particles human osteosarcoma (HOS) magneto-mechanical actuation (MMA) targeting destroying HOS cells. We show that MPs easily incorporated by ADSCs cells, confirmed TEM images ferrozine assay. MP-loaded display increased motility towards tumor compared with their unloaded counterparts. MMA induces destruction, MTT live/dead assays. enables release producing significant decrease (about 80%) in viability immediately after application. In contrast, normal dermal fibroblasts’ (NHDFs) exposed similar conditions remains high, showing differential behavior malignant MP load exposure. Taken together, method could derive successful strategies vivo applications while protecting
Language: Английский
Citations
2
ACS Omega, Journal Year: 2024, Volume and Issue: 9(28), P. 30518 - 30533
Published: July 1, 2024
The present study is aimed at developing an innovative method for efficient cancer cell destruction by exploiting the magnetomechanical actuation (MMA) of Fe-Cr-Nb-B magnetic particles (MPs), which are loaded with clinically approved chemotherapeutic drugs. To achieve this objective, Fe68.2Cr11.5Nb0.3B20 nanoparticles were produced mechanically grinding amorphous ribbon precursors same composition. These display high anisotropy, a parallelepipedic shape structure, and ferromagnetic behavior. MPs antitumoral drugs mitoxantrone (MTX) or doxorubicin (DOX). In our study, we used adipose-derived mesenchymal stem cells human osteosarcoma to test drug-loaded their biocompatibility, cytotoxicity, cellular internalization. Further tests involved exposing simultaneous MPs-targeted chemotherapy followed viability/death assays, such as MTT LDH, live/dead staining. Results demonstrate that death was induced synergistic action actuation. nanoparticle vehicles helped overcome drug resistance, decreasing dose in conventional therapies well time intervals needed MMA affect viability. proposed approach highlights possibility using new, targeted, effective treatment very few side effects.
Language: Английский
Citations
0
Published: May 5, 2024
Language: Английский
Citations
0
Journal of Biomedical Research & Environmental Sciences, Journal Year: 2022, Volume and Issue: 3(8), P. 905 - 907
Published: Sept. 1, 2022
High values of saturation magnetization at low magnetic field, along with anisotropy are the basic elements for increased effects magnetomechanical actuation on cancer cells. In this paper we present a brief comparison report Fe-Cr-Nb-B Magnetic Particles (MPs) and Fe-Co Nanowires (NWs) human osteosarcoma The purpose study is to evaluate best sites employ different types nanomaterials cell destruction through actuation.
Language: Английский
Citations
1
Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 227 - 257
Published: Jan. 1, 2023
Language: Английский
Citations
0
Published: May 1, 2023
Magneto-mechanical actuation induces the most destruction on cancer cells when employed magnetic nanomaterials with shape anisotropy as well high values of saturation magnetization. The aim this study is to compare effects nanoparticles and nanowires human osteosarcoma cells. In paper we present results obtained using Fe-(Cr/Ti/Mn)-Nb-B Ni-Fe Co-Fe for cell magneto-mechanical actuation.
Language: Английский
Citations
0