Magnetochemistry,
Journal Year:
2022,
Volume and Issue:
9(1), P. 12 - 12
Published: Dec. 30, 2022
Magnetic
nanocomposites
(MNCs)
combine
the
features
of
magnetic
nanoparticles
and
a
second
material,
which
provide
distinct
physical,
chemical,
biological
properties.
The
core
for
nanocomposite
synthesis
is
extensively
used
due
to
its
high
saturation
magnetization,
chemical
stability,
large
surface
area,
easy
functionalization.
Moreover,
(MNPs)
have
great
potential
resonance
imaging
(MRI),
particle
(MPI),
hyperthermia,
targeted
drug
gene
delivery
by
an
external
field.
Numerous
composing
units
exist,
leads
outstanding
application
composites.
This
review
focuses
on
nucleic
acid-based
bioapplications
MNCs
with
polymeric,
organic,
inorganic,
biomolecules,
bioinspared
coating.
In
addition,
different
forms,
such
as
core–shell,
doping,
multilayer,
yolk–shell,
Janus-shaped
hybrids,
are
discussed,
their
unique
properties
highlighted.
types
molecularly
imprinted
polymer
(MMIP)
presented.
presents
only
using
ready-made
cores.
These
restrictions
associated
many
materials,
quantitative
qualitative
composition,
procedures.
aims
discuss
MNC
information
available
researchers
in
this
field
guide
them
through
some
problems
structure
variation,
functionalization
possibilities.
most
recent
advancements
polymers
therapy,
diagnostics,
theranostics,
separation,
biocatalytic,
biosensing
introduced.
Results in Engineering,
Journal Year:
2024,
Volume and Issue:
23, P. 102473 - 102473
Published: June 28, 2024
This
study
investigated
the
use
of
magnetic
fluid
hyperthermia
(MFH)
for
treating
glioblastoma
multiforme
(GBM),
a
deadly
and
treatment-resistant
tumor.
It
considers
effects
nanoparticle
(MNP)
(different
sizes
materials),
alternating
field
(AMF)
characteristics
(frequency
strength
field),
MFH
duration,
injection
number,
using
realistic
brain
phantom,
considering
its
blood
circulation
system,
tumor,
healthy
tissue
properties.
Results
demonstrated
that
is
more
sensitive
to
frequency,
increasing
frequency
causing
greater
temperature
thermoablation
than
field.
The
can
be
increased
at
fixed
control
increase
in
mild
treatment
reliably.
size
MNP
significantly
impacts
when
exceeding
15.8
nm,
while
smaller
particles
do
not
affect
obtained.
Also,
tumor's
concentration
increases
uniformly
disperses
as
number
sites
increases.
examined
duration
(30–60
min),
it
important
optimize
prevent
irreparable
damage
cases
from
46
°C.
In
conclusion,
effectively
manage
generated
destruction
malignant
minimizing
tissue,
multiple
hyperthermia-related
parameters
must
adjusted
simultaneously.
Magnetochemistry,
Journal Year:
2023,
Volume and Issue:
9(4), P. 106 - 106
Published: April 12, 2023
Nanoplatforms
used
for
the
loading
of
anticancer
drugs
constitute
a
promising
approach
to
cancer
treatment
and
reducing
side
effects
these
drugs.
Among
cutting-edge
systems
in
this
area
are
magnetic
nanocomposites
(MNCs)
nanocapsules
(NCs).
MNCs
considered
smart
tool
magnetic-field-guided
targeted
drug
delivery,
resonance
imaging,
hyperthermia
therapy.
Nanocapsules
offer
great
potential
due
their
ability
control
drug-loading
capacity,
release
efficiency,
stability,
ease
with
which
surfaces
can
be
modified.
This
study
proposes
method
development
nylon-6-coated
nylon-6
polymeric
membrane
NCs.
A
biocompatible
polymer
was
first
NC
synthesis.
Oleic-acid-modified
non-modified
Fe3O4
nanoparticles
were
synthesized
production
nylon-coated
MNCs.
Dynamic
light
scattering
(DLS),
transmission
electron
microscopy
(TEM),
ζ-potential
measurements
perform
size,
morphology,
charge
analyses.
The
above-mentioned
two
types
templates
manufacture
nylon
nanocapsules,
leading
NCs
different
charges
structures.
developed
oleic-acid-coated
showed
excellent
values
chemotherapy
doxorubicin
(DOX)
up
732
943
µg/mg
(DOX/MNC
or
NC),
respectively.
On
contrary,
capacity
nano-construction
that
not
modified
oleic
acid
did
exceed
140
µg/mg.
DOX-loaded
nanosystems
displayed
pH-sensitive
properties,
highest
efficiency
observed
at
an
acidic
pH.
series
inhibited
A549
HEK
293FT
cell
lines,
lowest
IC50
value
0.31
µM
is
1.5-fold
lower
concentration
than
free
DOX.
Therefore,
presented
nanoscale
treatment.
Magnetochemistry,
Journal Year:
2022,
Volume and Issue:
9(1), P. 12 - 12
Published: Dec. 30, 2022
Magnetic
nanocomposites
(MNCs)
combine
the
features
of
magnetic
nanoparticles
and
a
second
material,
which
provide
distinct
physical,
chemical,
biological
properties.
The
core
for
nanocomposite
synthesis
is
extensively
used
due
to
its
high
saturation
magnetization,
chemical
stability,
large
surface
area,
easy
functionalization.
Moreover,
(MNPs)
have
great
potential
resonance
imaging
(MRI),
particle
(MPI),
hyperthermia,
targeted
drug
gene
delivery
by
an
external
field.
Numerous
composing
units
exist,
leads
outstanding
application
composites.
This
review
focuses
on
nucleic
acid-based
bioapplications
MNCs
with
polymeric,
organic,
inorganic,
biomolecules,
bioinspared
coating.
In
addition,
different
forms,
such
as
core–shell,
doping,
multilayer,
yolk–shell,
Janus-shaped
hybrids,
are
discussed,
their
unique
properties
highlighted.
types
molecularly
imprinted
polymer
(MMIP)
presented.
presents
only
using
ready-made
cores.
These
restrictions
associated
many
materials,
quantitative
qualitative
composition,
procedures.
aims
discuss
MNC
information
available
researchers
in
this
field
guide
them
through
some
problems
structure
variation,
functionalization
possibilities.
most
recent
advancements
polymers
therapy,
diagnostics,
theranostics,
separation,
biocatalytic,
biosensing
introduced.
