Electrospun nano-barium titanate/polycaprolactone composite coatings on titanium and Ti13Nb13Zr alloy DOI Creative Commons
Sabreen Waleed Ibrahim,

Thekra Ismael Hamad

Composites and Advanced Materials, Journal Year: 2023, Volume and Issue: 32

Published: Jan. 1, 2023

Using coated implant materials has been demonstrated to enhance bone regeneration and expedite healing around sites significantly. Generally, employing a polymeric matrix reinforced with ceramic considered promising composite material for the coating of implants. The present study aimed evaluate effect mixing varying concentrations nano-barium titanate (nanoBaTiO3) (9, 18, 36 wt%) polycaprolactone (PCL) (18 on properties coatings applied commercially pure titanium (CpTi) Ti13Nb13Zr alloys materials. electrospinning technique was utilised fabricate coatings, samples were characterised using atomic force microscopy (AFM) investigate coating’s surface roughness topography; incorporation high amount BaTiO3 resulted in increased layer CpTi (69.78 nm 96.88 nm, respectively). Field emission scanning electron (FE-SEM) used morphology; fibre diameters BT/PCL 80 534 different mixture concentrations. Fourier transform infrared spectroscopy (FTIR) verified chemical bonds coating. Results indicated that increasing proportion composition reduced water contact angles enhanced adhesion strength substrate. These findings provide valuable information developing new promote growth accelerate

Language: Английский

Electrospun Janus core (ethyl cellulose//polyethylene oxide) @ shell (hydroxypropyl methyl cellulose acetate succinate) hybrids for an enhanced colon-targeted prolonged drug absorbance DOI
Jianfeng Zhou, Tao Yi, Zhiyuan Zhang

et al.

Advanced Composites and Hybrid Materials, Journal Year: 2023, Volume and Issue: 6(6)

Published: Oct. 17, 2023

Language: Английский

Citations

79
Piezoelectric Effect Polyvinylidene Fluoride (PVDF): From Energy Harvester to Smart Skin and Electronic Textiles DOI
Zhangbin Feng, Ziquan Zhao, Yanan Liu

et al.

Advanced Materials Technologies, Journal Year: 2023, Volume and Issue: 8(14)

Published: May 5, 2023

Abstract With the great demand for flexible self‐powered sensors and nanogenerators, polyvinylidene fluoride (PVDF) is widely investigated outstanding piezoelectric dielectric constant. In pursuit increasing β content, electrospinning exhibited to be an effective method without external high voltage pooling or mechanical stretching thus considered a cost‐effective simple method, because molecular dipoles in PVDF can aligned during process of with field stretching. The methods improving characteristics are briefly introduced this review, fibers including uniaxial fibers, highly core–shell Janus revealed, research on theoretical modeling carried out efficiency design nanogenerator. Last, studies prospective applications based electrospun its copolymer PVDF‐TrFE, from smart skin, energy harvesters electronic textiles, being conducted.

Language: Английский

Citations

72
Electrosprayed Stearic-Acid-Coated Ethylcellulose Microparticles for an Improved Sustained Release of Anticancer Drug DOI Creative Commons

Yuexin Ji,

Hua Zhao,

Hui Liu

et al.

Gels, Journal Year: 2023, Volume and Issue: 9(9), P. 700 - 700

Published: Aug. 29, 2023

Sustained release is highly desired for "efficacious, safe and convenient" drug delivery, particularly those anticancer molecules with toxicity. In this study, a modified coaxial electrospraying process was developed to coat hydrophobic lipid, i.e., stearic acid (SA), on composites composed of the tamoxifen citrate (TC) insoluble polymeric matrix ethylcellulose (EC). Compared electrosprayed TC-EC composite microparticles M1, SA-coated hybrid M2 were able provide an improved TC sustained-release profile. The 30% 90% loaded time periods extended 3.21 h 19.43 M2, respectively, which significantly longer than provided by M1 (0.88 9.98 h, respectively). morphology, inner structure, physical state, compatibility components particles disclosed through SEM, TEM, XRD, FTIR. Based analyses, mechanism multiple factors co-acting suggested, include reasonable selections organizations lipid excipient, blank SA shell loading, regularly round shape, also high density. reported protocols pioneered brand-new manner developing sustained delivery hybrids combination cellulose gels using electrospraying.

Language: Английский

Citations

67
Three EHDA Processes from a Detachable Spinneret for Fabricating Drug Fast Dissolution Composites DOI Creative Commons
Chen Shu, Jianfeng Zhou,

Boya Fang

et al.

Macromolecular Materials and Engineering, Journal Year: 2023, Volume and Issue: 309(4)

Published: Nov. 23, 2023

Abstract In this study, three kinds of electrohydrodynamic atomization (EHDA) processes (electrospraying, electrospinning, and coaxial electrospinning) are implemented to create hydroxypropyl methylcellulose (HPMC) based ultra‐thin products for providing the fast dissolution a poorly water‐soluble drug ketoprofen (KET). An EHDA apparatus, characterized by novel spinneret, is homemade conducting processes. The types electrospun nanofibers E1, electrosprayed microparticles E2, core‐shell E3. SEM TEM results indicate that they have anticipated morphologies inner structures. X‐ray diffraction Fourier Transform Infrared verify KET mainly amorphous in all composites due its fine compatibility with HPMC. vitro tests demonstrate rapid release performances has an order E3>E1>E2≫KET powders. mechanisms suggested advantages compared. super performance E3 furnishing attributed synergistic action small size (of shell thickness), high porosity, state drug, solubility nanostructures can support development nano delivery systems (DDSs) through tailoring spatial distribution molecules within products.

Language: Английский

Citations

62
How can Electrospinning Further Service Well for Pharmaceutical Researches? DOI
Deng‐Guang Yu, Jianfeng Zhou

Journal of Pharmaceutical Sciences, Journal Year: 2023, Volume and Issue: 112(11), P. 2719 - 2723

Published: Aug. 27, 2023

Language: Английский

Citations

51
Recent Combinations of Electrospinning with Photocatalytic Technology for Treating Polluted Water DOI Open Access
He Lv, Yanan Liu,

Yubin Bai

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(4), P. 758 - 758

Published: April 15, 2023

Dyes, antibiotics, heavy metal ions, and bacteria are important sources of water pollution. How to solve these issues has become a problem in the fields science technology. People have developed variety technologies treat pollutants water. Photocatalytic technology came into being. As simple environmentally friendly treatment technology, it been widely studied by scientific community. Traditional powder photocatalysts cause secondary pollution environment not conducive recycling. Therefore, large specific surface area reusable membrane built electrospinning favorite today’s Nanofiber membranes prepared structures, which can meet needs different occasions. This review summarizes discusses research progress relationship between structure electrospun fiber membranes, their impacts on photocatalytic performance nanofiber membranes. The performance, challenges, future development directions with kinds techniques using photocatalysis pollutants, reviewed.

Language: Английский

Citations

46
Electrospun Biomolecule-Based Drug Delivery Systems DOI Creative Commons
Deng‐Guang Yu, Chang Huang

Biomolecules, Journal Year: 2023, Volume and Issue: 13(7), P. 1152 - 1152

Published: July 20, 2023

Drug delivery, mainly a professional term in pharmaceutics, is field of interdisciplinary intersection and integration [...].

Language: Английский

Citations

44
Dual-Step Controlled Release of Berberine Hydrochloride from the Trans-Scale Hybrids of Nanofibers and Microparticles DOI Creative Commons
Jianfeng Zhou,

Yelin Dai,

Junhao Fu

et al.

Biomolecules, Journal Year: 2023, Volume and Issue: 13(6), P. 1011 - 1011

Published: June 18, 2023

In this nano era, nanomaterials and nanostructures are popular in developing novel functional materials. However, the combinations of materials at micro macro scales can open new routes for trans-scale products with improved or even performances. work, a brand-new hybrid, containing both nanofibers microparticles, was fabricated using sequential electrohydrodynamic atomization (EHDA) process. Firstly, microparticles loaded drug (berberine hydrochloride, BH) molecules cellulose acetate (CA) were solution electrospraying Later, these suspended into co-dissolved that contained BH hydrophilic polymer (polypyrrolidone, PVP) co-electrospun nanofiber/microparticle hybrids. The EHDA processes recorded, resultant showed typical hybrid topography, distributed all over nanofibers, which demonstrated by SEM assessments. FTIR XRD components within hybrids presented an amorphous state had fine compatibility each other. vitro dissolution tests verified able to provide designed dual-step release profiles, combination fast step from PVP through erosion mechanism sustained insoluble CA via Fickian diffusion mechanism. present protocols pave way

Language: Английский

Citations

37
Biphasic drug release from electrospun structures DOI
Jianfeng Zhou, Pu Wang, Deng‐Guang Yu

et al.

Expert Opinion on Drug Delivery, Journal Year: 2023, Volume and Issue: 20(5), P. 621 - 640

Published: May 4, 2023

Introduction Biphasic release, as a special drug-modified release profile that combines immediate and sustained allows fast therapeutic action retains blood drug concentration for long periods. Electrospun nanofibers, particularly those with complex nanostructures produced by multi-fluid electrospinning processes, are potential novel biphasic delivery systems (DDSs).Areas covered This review summarizes the most recent developments in related structures. In this review, role of electrospun was comprehensively explored. These include monolithic nanofibers obtained through single-fluid blending electrospinning, core-shell Janus prepared via bifluid three-compartment trifluid nanofibrous assemblies layer-by-layer deposition combined structure nanofiber mats casting films. The strategies mechanisms which structures facilitate were analyzed.Expert opinion can provide many development DDSs. However, issues such scale-up productions nanostructures, vivo verification effects, keeping pace drawing support from state-of-the-art pharmaceutical excipients, combination traditional methods need to be addressed real applications.

Language: Английский

Citations

35
Electrospun core–sheath PCL nanofibers loaded with nHA and simvastatin and their potential bone regeneration applications DOI Creative Commons
Chenghui Qian, Yubo Liu, Si Chen

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11

Published: July 26, 2023

Drugs and biocompatible nanoparticles have raised significant potential in advancing the bone regeneration. Electrospinning technology enables full realization of value drugs nanoparticles.

Language: Английский

Citations

35