Dentistry Journal,
Journal Year:
2025,
Volume and Issue:
13(4), P. 179 - 179
Published: April 21, 2025
This
review
aims
to
provide
an
overview
of
the
types
membranes,
bone
substitutes,
and
mucosal
substitutes
used
for
GTR
GBR
briefly
explores
recent
innovations
tissue
regeneration
their
future
perspectives.
Since
this
is
a
narrative
review,
no
systematic
search,
meta-analysis,
or
statistical
analysis
was
conducted.
Using
biomaterials
provides
reduction
in
postoperative
morbidity,
as
it
contributes
less
invasive
clinical
procedures,
serving
alternative
autogenous
grafts.
Moreover,
randomized
trials
(RCTs)
reviews
are
essential
evaluation
new
biomaterials.
These
studies
more
robust
evidence
help
guide
practice
selection
safer
effective
biomaterials,
allowing
personalization
treatment
protocols
each
patient.
Chemical Engineering Journal,
Journal Year:
2024,
Volume and Issue:
488, P. 150631 - 150631
Published: March 26, 2024
The
skeletal
system
is
essential
for
preserving
body
structure
and
facilitating
mobility;
however,
bone
diseases
frequently
result
in
significant
disabilities,
necessitating
the
investigation
into
biomaterials
restoration.
Nevertheless,
these
may
elicit
immune
reactions
that
obstruct
healing
process.
Macrophages
assume
a
pivotal
role
modulating
inflammation
sustaining
homeostasis
regeneration.
A
comprehensive
understanding
of
molecular
interactions
between
macrophages
imperative
development
sophisticated
designed
to
regulate
environment
promote
remodeling.
This
review
delves
generation,
polarization,
interaction
with
principal
cell
types
implicated
osteogenesis,
detailing
mechanisms
by
which
influence
repair
their
response
biomaterials.
Additionally,
it
discusses
strategies
precise
modulation
macrophage
functionality
via
intelligent
mechanisms,
outlines
challenges
constraints
designing
integrate
functions.
By
elucidating
challenges,
lays
groundwork
creation
advanced
endowed
smart
immunomodulatory
capabilities,
heralding
novel
approaches
treatment
defects
advancement
regeneration
therapies.
Biomaterials Science,
Journal Year:
2024,
Volume and Issue:
12(18), P. 4546 - 4589
Published: Jan. 1, 2024
Bioactive
glasses
are
inorganic
biocompatible
materials
that
can
find
applications
in
many
biomedical
fields.
The
main
application
is
bone
and
dental
tissue
engineering.
However,
some
contact
with
soft
tissues
emerging.
It
well
known
both
bulk
(such
as
composition)
surface
properties
morphology
wettability)
of
an
implanted
material
influence
the
response
cells
implant.
This
review
aims
to
elucidate
compare
strategies
employed
modulate
cell
behavior
bioactive
glasses.
first
part
this
focused
on
doping
ions
drugs,
which
be
incorporated
into
bioceramic
impart
several
therapeutic
properties,
such
osteogenic,
proangiogenic,
or/and
antibacterial
ones.
second
devoted
chemical
functionalization
using
extra-cellular
matrix
proteins,
vitamins,
polyphenols.
In
third
final
part,
physical
modifications
surfaces
reviewed.
Both
top-down
(removing
from
surface,
for
example
laser
treatment
etching
strategies)
bottom-up
(depositing
through
deposition
coatings)
discussed.
Regenerative Biomaterials,
Journal Year:
2024,
Volume and Issue:
11
Published: Jan. 1, 2024
Abstract
The
intricate
nature
of
oral-maxillofacial
structure
and
function,
coupled
with
the
dynamic
oral
bacterial
environment,
presents
formidable
obstacles
in
addressing
repair
regeneration
bone
defects.
Numerous
characteristics
should
be
noticed
repair,
such
as
irregular
morphology
defects,
homeostasis
between
hosts
microorganisms
cavity
complex
periodontal
structures
that
facilitate
epithelial
ingrowth.
Therefore,
necessitates
restoration
materials
adhere
to
stringent
specific
demands.
This
review
starts
exploring
these
particular
requirements
by
introducing
bones
then
summarizes
classifications
current
respect
composition
structure.
Additionally,
we
discuss
modifications
including
improving
mechanical
properties,
optimizing
surface
topography
pore
adding
bioactive
components
elements,
compounds,
cells
their
derivatives.
Ultimately,
organize
a
range
potential
optimization
strategies
future
perspectives
for
enhancing
materials,
physical
environment
manipulation,
microbial
modulation,
osteo-immune
regulation,
smart
stimuli-responsive
multifaceted
approach
poly-pathic
treatment,
hope
providing
some
insights
researchers
this
field.
In
summary,
analyzes
demands
especially
alveolar
bone,
concludes
corresponding
biomaterials
aims
inspire
research
pursuit
more
effective
treatment
outcomes.
Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(5), P. 119 - 119
Published: April 29, 2024
Objective:
Dental
hypersensitivity
remains
widespread,
underscoring
the
need
for
materials
that
can
effectively
seal
dental
tubules.
This
study
evaluated
potential
of
bioactive-glass-infused
hydroxyethyl
cellulose
gels
in
this
context.
Methods:
Five
were
synthesized,
each
containing
20%
bioactive
glass
(specifically,
45S5,
S53P4,
Biomin
F,
and
C),
with
an
additional
blank
gel
serving
as
a
control.
Subjected
to
two
months
accelerated
aging
at
37
±
2
°C,
these
assessed
key
properties:
viscosity,
water
disintegration
time,
pH
level,
consistency,
adhesion
glass,
element
release
capability.
Results:
Across
board,
facilitated
calcium,
phosphate,
silicon
ions,
raising
from
9.00
0.10
9.7
0.0—a
range
conducive
remineralization.
Dissolution
occurred
within
30–50
min
post-application.
Viscosity
readings
showed
variability,
45S5
reaching
6337
24
mPa/s
F
3269
18
after
months.
Initial
was
measured
0.27
0.04
Pa,
increasing
0.73
0.06
Pa
others
over
time.
Gels
elements
upon
contact
(Ca−
C
104.8
15.7
mg/L;
Na−
76.30
11.44
P−
2.623
0.393
Si−
45S5-45.15
6.77mg/L,
F−
3.256
0.651mg/L;
Cl−
135.5
20.3
mg/L
45
min).
Conclusions:
These
findings
highlight
gels’
capacity
kickstart
remineralization
process
by
delivering
critical
ions
needed
enamel
layer
reconstruction.
Further
exploration
more
dynamic,
real-world
conditions
is
recommended
fully
ascertain
their
practical
utility.
