Functional Foods: Product Development, Technological Trends, Efficacy Testing, and Safety

Annual Review of Food Science and Technology, Journal Year: 2020, Volume and Issue: 11(1), P. 93 - 118

Published: Jan. 6, 2020

Functional foods is a very popular term in the social and scientific media; consequently, food producers have invested resources development of processed that may provide added functional benefits to consumers’ well-being. Because intrinsic regulation end-of-use purposes different countries, worldwide meanings definitions this are still unclear. Hence, here we standardize definition propose guideline attest some ingredients or truly deserve special designation. Furthermore, focus directed at most recent studies practical guidelines can be used develop test efficacy potentially ingredients. The widespread ingredients, such as polyunsaturated fatty acids (PUFAs), probiotics/prebiotics/synbiotics, antioxidants, their technological means delivery products described. review discusses steps companies should take ensure developed product functional.

Language: Английский

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Carotenoids: How Effective Are They to Prevent Age-Related Diseases?

Molecules, Journal Year: 2019, Volume and Issue: 24(9), P. 1801 - 1801

Published: May 9, 2019

Despite an increase in life expectancy that indicates positive human development, a new challenge is arising. Aging positively associated with biological and cognitive degeneration, for instance decline, psychological impairment, physical frailty. The elderly population prone to oxidative stress due the inefficiency of their endogenous antioxidant systems. As many studies showed inverse relationship between carotenoids age-related diseases (ARD) by reducing through interrupting propagation free radicals, carotenoid has been foreseen as potential intervention age-associated pathologies. Therefore, role counteract promote healthy aging worthy further discussion. In this review, we discussed underlying mechanisms involved prevention ARD. Collectively, understanding ARD would provide insights into may affect process, subsequently longevity.

Language: Английский

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Potential health benefits of carotenoid lutein: An updated review

Food and Chemical Toxicology, Journal Year: 2021, Volume and Issue: 154, P. 112328 - 112328

Published: June 8, 2021

Language: Английский

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Developing algae as a sustainable food source

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 9

Published: Jan. 19, 2023

Current agricultural and food production practices are facing extreme stress, posed by climate change an ever-increasing human population. The pressure to feed nearly 8 billion people while maintaining a minimal impact on the environment has prompted movement toward new, more sustainable sources. For thousands of years, both macro (seaweed kelp) micro (unicellular) forms algae have been cultivated as source. Algae evolved be highly efficient at resource utilization proven viable source nutritious biomass that could address many current issues. Particularly for microalgae, studies their large-scale growth cultivation come from biofuel industry; however, this knowledge can reasonably translated into algae-based products. ability sequester CO 2 lends its sustainability helping reduce carbon footprint production. Additionally, produced non-arable land using non-potable water (including brackish or seawater), which allows them complement rather than compete with traditional agriculture. inherently desired qualities because they produce digestible proteins, lipids, carbohydrates, rich in essential fatty acids, vitamins, minerals. Although yet fully domesticated sources, variety breeding tools exist built upon allow increased productivity enhanced nutritional organoleptic will required bring mainstream utilization. Here we focus microalgae cyanobacteria highlight advancements expand well outline various challenges between economic market.

Language: Английский

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Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action

Drug Design Development and Therapy, Journal Year: 2022, Volume and Issue: Volume 16, P. 23 - 66

Published: Jan. 1, 2022

Abstract: The skin is the largest organ in human body, composed of epidermis and dermis. It provides protection acts as a barrier against external menaces like allergens, chemicals, systemic toxicity, infectious organisms. Skin disorders cancer, dermatitis, psoriasis, wounds, aging, acne, infection occur frequently can impact life. According to growing body evidence, several studies have reported that natural products potential for treating disorders. Building on this information, review brief information about action most important vitro vivo research use ten selected inflammatory, neoplastic, their mechanisms been date. related articles were searched from databases, including PubMed, Google, Google Scholar, ScienceDirect. Ten widely reviewed study, with showing anti-inflammatory, antioxidant, anti-microbial, anti-cancer effects main therapeutic actions. Overall, reduce suppress inflammatory markers, tumor necrosis factor-alpha (TNF-α), scavenge reactive oxygen species (ROS), induce cancer cell death through apoptosis, prevent bacteria, fungal, virus infections indicating potentials. This also highlighted challenges opportunities transdermal/topical delivery systems safety considerations Our findings indicated might be low-cost, well-tolerated, safe treatment diseases. However, larger number clinical trials are required validate these findings. Natural combination modern drugs, well development novel mechanisms, represent very promising area future drug discovery leads Keywords: products, disorder,

Language: Английский

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Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp.

Bioengineering, Journal Year: 2023, Volume and Issue: 10(8), P. 955 - 955

Published: Aug. 11, 2023

Chlorella sp. and Spirulina (Arthrospira) account for over 90% of the global microalgal biomass production represent one most promising aquiculture bioeconomy systems. These microorganisms have been widely recognized their nutritional therapeutic properties; therefore, a significant growth market is expected, especially in nutraceutical, food, beverage segments. However, recent advancements biotechnology environmental science led to emergence new applications these microorganisms. This paper aims explore innovative applications, while shedding light on roles sustainable development, health, industry. From this state-of-the art review, it was possible give an in-depth outlook sustainability For instance, there variety studies reported use two wastewater treatment biofuel production, contributing climate change mitigation efforts. Moreover, health sector, richness microalgae photosynthetic pigments bioactive compounds, along with oxygen-releasing capacity, are being harnessed development drugs, wound-healing dressings, photosensitizers photodynamic therapy, tissue engineering, anticancer treatments. Furthermore, industrial used biopolymers, fuel cells, photovoltaic technologies. might bring different outlets valorization, enhancing potential, since sector presents issues such as high costs. Thus, further research highly needed fully benefits potential various sectors.

Language: Английский

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Natural dietary ROS scavenger-based nanomaterials for ROS-related chronic disease prevention and treatment

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 490, P. 151756 - 151756

Published: April 30, 2024

Language: Английский

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Oxidative Stress in Age-Related Macular Degeneration: Nrf2 as Therapeutic Target

Frontiers in Pharmacology, Journal Year: 2018, Volume and Issue: 9

Published: Nov. 4, 2018

Age-related macular degeneration is one of the leading causes vision loss in elderly. Genetics, environmental insults, and age-related issues are risk factors for development disease. All these linked to induction oxidative stress. In young subjects retinal pigment epithelial cells mitigate reactive oxygen generation by elimination dysfunctional mitochondria, via mitophagy, increasing antioxidant defences Nrf2 activation. The high amount UV light absorbed retina, together with cigarette smoking, cooperate aging process increase species generated epithelium where stress arises. Moreover, elderly both mitophagic activation impaired thus causing cell death. This review will focus on impact pathogenesis analyse natural synthetic Nrf2-activating compounds that have been tested as potential therapeutic agents

Language: Английский

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Functional food products in Japan: A review

Food Science and Human Wellness, Journal Year: 2019, Volume and Issue: 8(2), P. 96 - 101

Published: March 30, 2019

Japan has a long history of using foods with health benefits and Japanese people are well-known for their longevity. In 1991, the Ministry Health, Labor Welfare introduced functional food regulation called "foods specified uses" (FOSHU) in Japan. After introduction system, many clinically proven FOSHU products have been developed launched market. As result, net sales reached 6.2 billion dollars 2007. Most claims relate to improving gastro-intestinal probiotics. Triglycerides, high blood pressure, LDL-cholesterol, glucose mainly associated related claims. 2007, market was almost saturated. However, novel regulatory system\called "Foods Function Claims" established 2015 based on Dietary Supplement Health Education Act system USA. Major new fatigue, eyes, memory, stress, sleep, joints, flow, body temperature, muscles, Body Mass Index. total including 8 2018. The is more flexible terms claims, protocol clinical studies, required results. Therefore, still growing. present paper, potential both systems some issues will be discussed.

Language: Английский

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Terpenoids as Potential Geroprotectors

Antioxidants, Journal Year: 2020, Volume and Issue: 9(6), P. 529 - 529

Published: June 17, 2020

Terpenes and terpenoids are the largest groups of plant secondary metabolites. However, unlike polyphenols, they rarely associated with geroprotective properties. Here we evaluated conformity biological effects criteria geroprotectors, including primary (lifespan-extending in model organisms, improvement aging biomarkers, low toxicity, minimal adverse effects, quality life) (evolutionarily conserved mechanisms action, reproducibility on different models, prevention age-associated diseases, increasing stress-resistance). The number substances that demonstrate greatest compliance both geroprotectors were found among classes terpenoids. Thus, an underestimated source potential can effectively influence age-related diseases.

Language: Английский

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