Antioxidant-Rich Functional Foods and Exercise: Unlocking Metabolic Health Through Nrf2 and Related Pathways DOI Open Access
Halyna Tkachenko, Natalia Kurhaluk

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1098 - 1098

Published: Jan. 27, 2025

This article reviews the synergistic effects of antioxidant-enriched functional foods and exercise in improving metabolic health, focusing on underlying molecular mechanisms. The review incorporates evidence from PubMed, SCOPUS, Web Science, PsycINFO, reference lists relevant up to 20 December 2024, highlighting central role Nrf2 pathway. As a critical regulator oxidative stress adaptation, mediates benefits these interventions. presents an innovative approach understanding regulation inflammation, its potential prevention treatment various diseases, including cancer, neurodegenerative disorders, cardiovascular pulmonary diabetes, inflammatory conditions, ageing, infections such as COVID-19. novelty this study is investigate bioactive compounds found (such polyphenols, flavonoids, vitamins) exercise-induced activation combined reveals their improve insulin sensitivity lipid metabolism reduce offering promising strategy for management chronic diseases. However, there are significant gaps current research, particularly regarding mechanisms interaction between diet, physical activity, activation, well long-term different populations, those with In addition, interactions other signalling pathways, AMPK, NF-κB, PI3K/Akt, collective contributions health explored. Furthermore, novel biomarkers presented assess impact strategies, NAD+/NADH ratio, GSH markers mitochondrial health. findings provide valuable insights into how integration antioxidant-rich diet regular can by activating related pathways represent strategies disorders. Further studies needed fully understand therapeutic interventions diseases stress, disease, cancer.

Language: Английский

Seaweeds as a Functional Ingredient for a Healthy Diet DOI Creative Commons
Rocío Peñalver, José M. Lorenzo, Gaspar Ros

et al.

Marine Drugs, Journal Year: 2020, Volume and Issue: 18(6), P. 301 - 301

Published: June 5, 2020

Seaweeds have been used since ancient times as food, mainly by Asian countries, while in Western their main application has gelling agents and colloids for the pharmaceuticals, cosmetic industry. are a good source of nutrients such proteins, vitamins, minerals, dietary fiber. Polyphenols, polysaccharides, sterols, well other bioactive molecules, responsible healthy properties associated with seaweed. Antioxidant, anti-inflammatory, anti-cancer, anti-diabetic attributed to these compounds. If seaweeds compared terrestrial plants, they higher proportion essential fatty acids eicosapentaenoic (EPA) docosahexaenoic (DHA) acids. In addition, there several secondary metabolites that synthesized algae terpenoids, oxylipins, phlorotannins, volatile hydrocarbons, products mixed biogenetic origin. Therefore, can be considered natural great interest, contain compounds numerous biological activities functional ingredient many technological applications obtain foods.

Language: Английский

Citations

340

Consumer Acceptance toward Functional Foods: A Scoping Review DOI Open Access
Matt Baker, Peng Lu, Jean A. Parrella

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(3), P. 1217 - 1217

Published: Jan. 22, 2022

Chronic diseases (e.g., heart disease, cancer, diabetes) are of major public concern. Such chronic often caused by a dietary pattern characterized as relatively high in fat, refined sugar, salt, and cholesterol. Societal interest consuming healthy foods the demand for food products have increased significantly. As result, functional gained significant research attention health technology innovations field. To date, many studies investigated factors that may predict consumer acceptance foods, wide range influential been reported. However, conducted different contexts pose challenges to gaining clear understanding influencing acceptance. Therefore, purpose our scoping review was synthesize possible determinants toward provide resource describes global trends regarding consumers' behavior. We identified 75 articles published with varying populations around globe empirically foods. categorized related types The five categories were product characteristics, socio-demographic psychological behavioral physical characteristics. Each more fully described sub-determinants review. These should be considered used leaders scientists development aid decision making and, ultimately, successful launch novel

Language: Английский

Citations

209

Effectiveness of probiotics, prebiotics, and prebiotic‐like components in common functional foods DOI
Mengfei Peng, Zajeba Tabashsum,

Mary Anderson

et al.

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2020, Volume and Issue: 19(4), P. 1908 - 1933

Published: May 26, 2020

Abstract The bioactive ingredients in commonly consumed foods include, but are not limited to, prebiotics, prebiotic‐like components, probiotics, and postbiotics. functional have also been associated with beneficial effects on human health. For example, they aid shaping of gut microflora promotion immunity. These components contribute preventing serious diseases such as cardiovascular malfunction tumorigenesis. However, the specific mechanisms these positive influences health still under investigation. In this review, we aim to emphasize major contents found consumable foods, present an overview direct indirect benefits provide contributors certain families metabolites, specifically short‐chain fatty acids polyunsaturated produced by or flavonoids, polyphenols, vitamins that foods. influence microbiota stimulating growth microbes production metabolites that, turn, host, while providing protection from pathogens maintaining a balanced ecosystem. complex interactions arise among food ingredients, physiology, microbiota, their respective metabolic pathways minimize several factors incidence chronic disease, inflammation oxidative stress.

Language: Английский

Citations

198

Micro and nano-encapsulation of vegetable and essential oils to develop functional food products with improved nutritional profiles DOI

Rana Delshadi,

Akbar Bahrami,

Abolfazl Golshan Tafti

et al.

Trends in Food Science & Technology, Journal Year: 2020, Volume and Issue: 104, P. 72 - 83

Published: July 21, 2020

Language: Английский

Citations

168

Novel strategy for developing healthy meat products replacing saturated fat with oleogels DOI
María López‐Pedrouso, José M. Lorenzo, Beatriz Gullón

et al.

Current Opinion in Food Science, Journal Year: 2020, Volume and Issue: 40, P. 40 - 45

Published: June 30, 2020

Language: Английский

Citations

167

Seaweeds as promising resource of bioactive compounds: Overview of novel extraction strategies and design of tailored meat products DOI
Beatriz Gullón, Mohammed Gagaoua, Francisco J. Barba

et al.

Trends in Food Science & Technology, Journal Year: 2020, Volume and Issue: 100, P. 1 - 18

Published: March 31, 2020

Language: Английский

Citations

166

Recent Advances in Health Benefits of Bioactive Compounds from Food Wastes and By-Products: Biochemical Aspects DOI Open Access
Valeria Sorrenti,

Ilaria Burò,

Valeria Consoli

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(3), P. 2019 - 2019

Published: Jan. 19, 2023

Bioactive compounds, including terpenoids, polyphenols, alkaloids and other nitrogen-containing constituents, exert various beneficial effects arising from their antioxidant anti-inflammatory properties. These compounds can be found in vegetables, fruits, grains, spices derived foods beverages such as tea, olive oil, fruit juices, wine, chocolate beer. Agricultural production the food supply chain are major sources of wastes, which become resources, they rich bioactive compounds. The aim this review is to highlight recent articles demonstrating numerous potential uses products by-products agro-food chain, have applications.

Language: Английский

Citations

150

Nutraceuticals in Neurological Disorders DOI Open Access
Rashita Makkar, Tapan Behl,

Simona Bungău

et al.

International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(12), P. 4424 - 4424

Published: June 22, 2020

Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes associated with drastically increased risk chronic illness and diseases, posing a substantial financial burden to society globally. Researchers aim provide fine treatment for ailing disorders minimal exposed side effects. In recent decades, several studies on functional foods have been initiated obtain that fewer effects therapeutic activity. Hence, an attempt has made unravel extraction techniques acquire essential bioactive compounds or phytochemicals from therapeutically active food products. This led conception term being meddled other similar terms like “pharmafoods,” “medifoods”, “vitafoods”, “medicinal foods”. With dire need adhere towards healthy options, demand nutraceuticals is widely increasing combat neurological interventions. An association between habits individual neurodegeneration manifested, thereby proposing role as prophylactic The current review covers some nutraceutical therapy in prevention disease.

Language: Английский

Citations

145

Seaweed for climate mitigation, wastewater treatment, bioenergy, bioplastic, biochar, food, pharmaceuticals, and cosmetics: a review DOI Creative Commons
Mohamed Farghali, Israa M. A. Mohamed, Ahmed I. Osman

et al.

Environmental Chemistry Letters, Journal Year: 2022, Volume and Issue: 21(1), P. 97 - 152

Published: Oct. 8, 2022

Abstract The development and recycling of biomass production can partly solve issues energy, climate change, population growth, food feed shortages, environmental pollution. For instance, the use seaweeds as feedstocks reduce our reliance on fossil fuel resources, ensure synthesis cost-effective eco-friendly products biofuels, develop sustainable biorefinery processes. Nonetheless, in several biorefineries is still infancy stage compared to terrestrial plants-based lignocellulosic biomass. Therefore, here we review seaweed with focus production, economical benefits, feedstock for anaerobic digestion, biochar, bioplastics, crop health, food, livestock feed, pharmaceuticals cosmetics. Globally, could sequester between 61 268 megatonnes carbon per year, an average 173 megatonnes. Nearly 90% sequestered by exporting deep water, while remaining 10% buried coastal sediments. 500 gigatonnes replace nearly 40% current soy protein production. Seaweeds contain valuable bioactive molecules that be applied antimicrobial, antioxidant, antiviral, antifungal, anticancer, contraceptive, anti-inflammatory, anti-coagulants, other cosmetics skincare products.

Language: Английский

Citations

140

Recent developments in valorisation of bioactive ingredients in discard/seafood processing by-products DOI
Fatih Özoğul, Martina Čagalj, Vida Šimat

et al.

Trends in Food Science & Technology, Journal Year: 2021, Volume and Issue: 116, P. 559 - 582

Published: Aug. 14, 2021

Language: Английский

Citations

130