Early‐Life Gut Microbiome—The Importance of Maternal and Infant Factors in Its Establishment DOI
Fatemeh Ramezani Kapourchali, Gail Cresci

Nutrition in Clinical Practice, Journal Year: 2020, Volume and Issue: 35(3), P. 386 - 405

Published: April 24, 2020

Abstract The early‐life microbiome is gaining appreciation as a major influencer in human development and long‐term health. Multiple factors are known to influence the initial colonization, development, function of neonatal gut microbiome. In addition, alterations microbial composition associated with several chronic health conditions such obesity, asthma, allergies. this review, we focus on both maternal infant colonization. Also reviewed important role feeding, including evidence‐based strategies for supplementation goal protect and/or restore

Language: Английский

A Comprehensive Review of the Triangular Relationship among Diet–Gut Microbiota–Inflammation DOI Open Access
Nidesha Randeni, Matteo Bordiga, Baojun Xu

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(17), P. 9366 - 9366

Published: Aug. 29, 2024

The human gastrointestinal tract hosts a complex and dynamic community of microorganisms known as the gut microbiota, which play pivotal role in numerous physiological processes, including digestion, metabolism, immune function. Recent research has highlighted significant impact diet on microbiota composition functionality, consequential effects host health. Concurrently, there is growing evidence linking to inflammation, key factor many chronic diseases such inflammatory bowel disease (IBD), obesity, diabetes, cardiovascular (CVDs). This review explores how dietary components influence composition, these microbial changes affect pathways, therapeutic implications modulating this axis for prevention management. Beneficial patterns, Mediterranean (MD) plant-based diets, promote diverse balanced supporting anti-inflammatory pathways. Conversely, Western (WD), high saturated fats refined sugars, associated with dysbiosis increased inflammation. With all links between three variables considered, attempts offer thorough examination triangle formed by food.

Language: Английский

Citations

18

Betulinic acid from Inonotus obliquus ameliorates T2DM by modulating short-chain fatty acids producing bacteria and amino acids metabolism in db/db mice DOI

Bing Lin,

Guangjian Bai,

Yifan Zhang

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119417 - 119417

Published: Jan. 1, 2025

Language: Английский

Citations

2

The Detrimental Impact of Ultra-Processed Foods on the Human Gut Microbiome and Gut Barrier DOI Open Access
D. Rondinella, Pauline Raoul,

Eleonora Valeriani

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 859 - 859

Published: Feb. 28, 2025

Ultra-processed foods (UPFs) have become a widely consumed food category in modern diets. However, their impact on gut health is raising increasing concerns. This review investigates how UPFs the microbiome and barrier, emphasizing dysbiosis increased permeability. UPFs, characterized by high content of synthetic additives emulsifiers, low fiber content, are associated with decrease microbial diversity, lower levels beneficial bacteria like Akkermansia muciniphila Faecalibacterium prausnitzii, an increase pro-inflammatory microorganisms. These alterations community contribute to persistent inflammation, which various chronic disorders including metabolic syndrome, irritable bowel type 2 diabetes, colorectal cancer. In addition, may alter gut-brain axis, potentially affecting cognitive function mental health. Dietary modifications incorporating fiber, fermented foods, probiotics can help mitigate effects UPFs. Furthermore, public needs stricter regulations for banning along well-defined labels. Further studies necessary elucidate mechanisms connecting systemic illnesses, thereby informing evidence-based dietary guidelines.

Language: Английский

Citations

2

Gut-Muscle Axis Exists and May Affect Skeletal Muscle Adaptation to Training DOI Open Access
Katarzyna Przewłócka, Marcin Folwarski, Karolina Kaźmierczak-Siedlecka

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 12(5), P. 1451 - 1451

Published: May 18, 2020

Excessive training may limit physiological muscle adaptation through chronic oxidative stress and inflammation. Improper diet overtraining also disrupt intestinal homeostasis in consequence enhance Altogether, these factors lead to an imbalance the gut ecosystem, causing dysregulation of immune system. Therefore, it seems be important optimize microbiota composition, which is able modulate system reduce stress. Moreover, optimal composition have impact on protein synthesis mitochondrial biogenesis function, as well glycogen storage. Aproperly balanced microbiome inflammatory markers reactive oxygen species production, further attenuate macromolecules damage. Consequently, supplementation with probiotics some beneficial effect aerobic anaerobic performance. The phenomenon gut-muscle axis should continuously explored function maintenance, not only athletes.

Language: Английский

Citations

107

Early‐Life Gut Microbiome—The Importance of Maternal and Infant Factors in Its Establishment DOI
Fatemeh Ramezani Kapourchali, Gail Cresci

Nutrition in Clinical Practice, Journal Year: 2020, Volume and Issue: 35(3), P. 386 - 405

Published: April 24, 2020

Abstract The early‐life microbiome is gaining appreciation as a major influencer in human development and long‐term health. Multiple factors are known to influence the initial colonization, development, function of neonatal gut microbiome. In addition, alterations microbial composition associated with several chronic health conditions such obesity, asthma, allergies. this review, we focus on both maternal infant colonization. Also reviewed important role feeding, including evidence‐based strategies for supplementation goal protect and/or restore

Language: Английский

Citations

92