Feasibility of a supervised and home‐based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy DOI Open Access
Annemieke Kok, Ellen Passchier, Anne M. May

et al.

European Journal of Cancer Care, Journal Year: 2022, Volume and Issue: 31(6)

Published: Aug. 11, 2022

Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with high toxicity that adversely affects physical functioning, body composition, fatigue, quality of life treatment outcomes. Exercise interventions during might counteract these negative effects. We therefore assessed the feasibility an exercise programme HNC patients CRT.Forty were offered a tailored 10-week endurance resistance training supervised home-based sessions. Feasibility endpoints (1) adherence (main outcome): ≥60% attendance; (2) recruitment: ≥30%; (3) retention rate: ≥85% (4) compliance ≥60%. Physical performance, muscle strength, fatigue pre- post-intervention.Overall was 54%. The recruitment rate 36%, 65%. Compliance to intervention protocol 66%. Statistically significant decreases found in mean grip fat-free mass clinically relevant deteriorations on several domains life, subscales found.We conclude this CRT its current form feasible only minority patients. suggest adaptations improve rates definitive multicentre trial.This study registered at Netherlands Trial Register (NTR7305), 6 June 2018, retrospectively registered.

Language: Английский

Role of Prehabilitation and Rehabilitation on Functional Recovery and Quality of Life in Thyroid Cancer Patients: A Comprehensive Review DOI Open Access
Lorenzo Lippi, Alessio Turco, Stefano Moalli

et al.

Cancers, Journal Year: 2023, Volume and Issue: 15(18), P. 4502 - 4502

Published: Sept. 10, 2023

Background: This narrative review aims to provide a comprehensive overview of the current prehabilitation and rehabilitation strategies for thyroid cancer survivors optimize functional outcomes enhance their quality life. Methods: The follows SANRA criteria includes an extensive literature search conducted in PubMed/Medline, Web Science, Scopus. Results: emphasizes role approach targeting different domains that generate disability patients. In this context, physical activity, range motion exercises, myofascial release, joint mobilization, postural exercises are crucial improving reducing treatment-related discomfort disability. Moreover, tailored rehabilitative management addressing dysphonia dysphagia might have positive impact on life these Despite considerations, several barriers still affect implementation multimodal common clinical practice. Thus, sustainable effective like digital innovation patient-centered approaches strongly needed order implement treatment framework subjects. Conclusions: provides valuable insights into treat survivors, physical, psychological, vocational needs

Language: Английский

Citations

7

Nutritional Deficiencies in Radiotherapy-Treated Head and Neck Cancer Patients DOI Open Access
Tomasz Powrózek,

Joanna Dziwota,

Teresa Małecka‐Massalska

et al.

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(4), P. 574 - 574

Published: Feb. 3, 2021

Nutritional deficiencies (malnutrition, cachexia, sarcopenia, and unfavorable changes in the body composition) developing as a side effect of radiotherapy (RT) currently represents significant but still inaccurately studied clinical problem cancer patients. The incidence malnutrition observed head neck (HNC) patients oncological radiology departments can reach 80%. presence malnutrition, cachexia is associated with an prognosis disease, higher mortality, deterioration quality life. Therefore, it necessary to identify high risk both metabolic syndromes. However, number studies investigating potential predictive markers for mentioned purposes significantly limited. This literature review summarizes nutritional HNC prior therapy after commencement RT, presents recent perspectives prediction result applied RT.

Language: Английский

Citations

17

The Value of the Nutritional Indicators in Predicting Free Flap Failure From a Multicentre Database DOI Creative Commons

Yuan‐Hao Yen,

Sheng‐Dean Luo, Wei‐Chih Chen

et al.

Otolaryngology, Journal Year: 2024, Volume and Issue: 171(1), P. 63 - 72

Published: March 19, 2024

Nutritional and inflammatory statuses have been associated with complications in microvascular-free flaps during head neck surgeries. This study aimed to evaluate the potential of nutritional indicators predicting postoperative free flap complications.

Language: Английский

Citations

2

Nutritional interventions in children with acute lymphoblastic leukemia undergoing antineoplastic treatment: a systematic review DOI Creative Commons

Alan E. Guzmán-León,

Jessica Avila-Prado,

Leslie Bracamontes-Picos

et al.

BMC Nutrition, Journal Year: 2024, Volume and Issue: 10(1)

Published: June 19, 2024

Abstract Background A compromised nutritional status jeopardizes a positive prognosis in acute lymphoblastic leukemia (ALL) patients. In low- and middle-income countries, ~ 50% of children with ALL are malnourished at diagnosis time, undergoing antineoplastic treatment increases the risk depleting their nutrient stores. Nutrition interventions implemented patients cancer related malnutrition. We aimed to evaluate effect nutrition diagnosed under treatment. Methods Using predefined protocol, we searched for published or unpublished randomized controlled trials in: Cochrane CENTRAL, MEDLINE, EMBASE, LILACS, SciELO, conducted complementary searches. Studies where least participants had an ≤ 18 years, active treatment, intervention were included. Study selection data extraction independently by three reviewers, assessment bias two reviewers. Results synthesized both tabular format narratively. Twenty-five studies (out 4097 records) satisfied inclusion requirements. There was high eighteen studies. Interventions analyzed classified compound/food ( n = 14), micronutrient 8), support 3). Within each group components (dose time) tested heterogeneous. relation our primary outcomes, none reported fat-free mass as outcome. Inflammatory metabolic markers anthropometric measurements many but varied greatly across For secondary fat total body water not outcome any However, some different adverse events Conclusions This review highlights need conduct high-quality ALL, based on limited number heterogeneous outcomes. Registration protocol Guzmán-León AE, Lopez-Teros V, Avila-Prado J, Bracamontes-Picos L, Haby MM, Stein K. Protocol Systematic Review: Nutritional tineoplastic International prospective register systematic reviews. 2021; PROSPERO CRD:42,021,266,761 https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=266761 ).

Language: Английский

Citations

2

Feasibility of a supervised and home‐based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy DOI Open Access
Annemieke Kok, Ellen Passchier, Anne M. May

et al.

European Journal of Cancer Care, Journal Year: 2022, Volume and Issue: 31(6)

Published: Aug. 11, 2022

Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with high toxicity that adversely affects physical functioning, body composition, fatigue, quality of life treatment outcomes. Exercise interventions during might counteract these negative effects. We therefore assessed the feasibility an exercise programme HNC patients CRT.Forty were offered a tailored 10-week endurance resistance training supervised home-based sessions. Feasibility endpoints (1) adherence (main outcome): ≥60% attendance; (2) recruitment: ≥30%; (3) retention rate: ≥85% (4) compliance ≥60%. Physical performance, muscle strength, fatigue pre- post-intervention.Overall was 54%. The recruitment rate 36%, 65%. Compliance to intervention protocol 66%. Statistically significant decreases found in mean grip fat-free mass clinically relevant deteriorations on several domains life, subscales found.We conclude this CRT its current form feasible only minority patients. suggest adaptations improve rates definitive multicentre trial.This study registered at Netherlands Trial Register (NTR7305), 6 June 2018, retrospectively registered.

Language: Английский

Citations

9