International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(3), P. 2957 - 2957
Published: Feb. 3, 2023
SARS-CoV-2
is
the
virus
that
causes
infectious
disease
known
as
Corona
Virus
Disease
2019
(COVID-19).
The
severe
impact
of
on
humans
undeniable,
which
why
effective
vaccines
were
highly
anticipated.
As
12
January
2022,
nine
have
obtained
Emergency
Use
Listing
by
World
Health
Organization
(WHO),
and
four
these
are
approved
or
authorized
Centers
for
Control
Prevention
(CDC)
in
United
States.
initial
clinical
trials
studying
COVID-19
vaccine
efficacy
excluded
pregnant
lactating
individuals,
meaning
data
effects
breast
milk
lacking.
Until
today,
none
been
use
individuals
under
six
months.
During
first
months
life,
babies
do
not
produce
their
own
antibodies;
therefore,
antibodies
contained
mothers’
breastmilk
a
critical
protective
mechanism.
Several
studies
shown
presence
women
who
vaccinated
had
naturally
infected.
However,
whether
still
unclear.
Additionally,
research
BNT162b2
mRNA
developed
Pfizer-BioNTech
mRNA-1273
Moderna
suggests
release
significant
amounts,
if
any,
into
milk.
Hence,
there
no
evidence
vaccination
mother
poses
any
risk
to
breastfed
infant,
while
present
may
offer
protection
against
virus.
primary
objective
this
systematic
review
summarize
current
understanding
immunoglobulins
human
elicited
evaluate
ability
neutralize
we
aim
quantify
side
experienced
mothers
vaccinated,
well
potential
adverse
infants.
This
study
because
it
can
help
inform
decision-making
examining
antibody
secretion
breastmilk.
particularly
important
because,
although
tends
be
less
younger
infants
contract
at
higher
requiring
hospitalization
compared
older
children.
Nutrients,
Journal Year:
2021,
Volume and Issue:
13(9), P. 3071 - 3071
Published: Aug. 31, 2021
Researchers
have
recently
called
for
human
lactation
research
to
be
conceptualized
as
a
biological
framework
where
maternal
and
infant
factors
impacting
milk,
in
terms
of
composition,
volume
energy
content
are
studied
along
with
relationships
growth,
development
health.
This
approach
allows
the
evidence-based
interventions
that
more
likely
support
breastfeeding
pursuit
global
goals.
Here
we
summarize
seminal
findings
our
programme
using
systems
traversing
breast
anatomy,
milk
secretion,
physiology
removal
respect
expression,
composition
intake,
gastric
emptying,
culminating
exploration
body
has
allowed
translation
education,
clinical
practice.
It
also
sets
foundation
improved
study
design
future
investigations
lactation.
Food Science of Animal Resources,
Journal Year:
2022,
Volume and Issue:
42(3), P. 351 - 371
Published: March 11, 2022
Milk
fats
are
present
as
globules
emulsified
in
the
aqueous
phase
of
milk
and
stabilized
by
a
delicate
membrane
architecture
called
fat
globule
(MFGM).
The
unique
structure
composition
MFGM
play
an
important
role
digestion
metabolic
programming
neonates.
objective
this
review
is
to
compare
structure,
composition,
physicochemical
characteristics
human
milk,
bovine
infant
formula.
It
provides
overview
process
enzymes
healthy
infants,
describes
possible
roles
association
with
factors
affecting
digestion.
Lastly,
health
benefits
on
nutrition
future
perspectives
discussed
focus
brain
development,
response,
gut
health.
The Science of The Total Environment,
Journal Year:
2022,
Volume and Issue:
831, P. 154888 - 154888
Published: March 30, 2022
Perfluorinated
alkyl
substances
(PFAS)
were
determined
in
human
milk
samples
(n
=
664)
from
participants
the
Maternal-Infant
Research
on
Environmental
Chemicals
(MIREC)
study.
ΣPFAS
concentrations
(sum
of
seven
PFAS)
ranged
3.1
ng
L-1
to
603
L-1,
with
a
median
concentration
106
Canadian
mothers'
analyzed.
These
data
comprise
first
pan-Canadian
dataset
PFAS
milk.
Perfluorooctanoic
acid
(PFOA)
and
linear
perfluorooctanesulfonate
(L-PFOS)
dominant
contributors
samples.
An
inverse
relationship
between
age
was
observed
(Spearman
correlation
-
0.184).
Primiparous
women
had
elevated
relative
who
children
previously
(p
<
0.001).
In
contrast,
region
maternal
birth
did
not
influence
0.156).
Although
China
Norway
have
consistently
detectable
levels
perfluoroundecanoic
(PFUdA)
milk,
long
carbon
chains
≥
11)
present
above
method
detection
limits
analyzed
as
part
MIREC
conclusion,
despite
presence
low
environmental
contaminants
Health
Canada
supports
breastfeeding
due
benefits
both
infants
mothers.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2022,
Volume and Issue:
64(17), P. 5748 - 5767
Published: Dec. 19, 2022
Human
milk
is
universally
regarded
as
the
gold
standard
to
fulfill
nutrition
needs
of
infants.
Lactoferrin
(LF)
a
major
multiple
bioactive
glycoprotein
in
human
but
little
presented
infant
formula.
LF
can
resist
digestion
gastrointestinal
tract
and
absorbed
into
bloodstream
an
intact
form
perform
physiological
functions.
Evidence
suggest
that
prevents
pathogen
infection,
promotes
immune
system
development,
intestinal
brain
development
bone
health,
well
ameliorates
iron
deficiency
anemia.
However,
more
clinical
studies
need
be
further
elucidated
determine
appropriate
dosage
for
application
sensitive
denaturation
induced
by
processing
formula
such
heat
treatments
spay
drying.
Thus,
should
focus
on
maximizing
retention
activity
process.
This
review
summarizes
structural
features
LF.
Then
digestion,
absorption
metabolism
infants
are
discussed,
followed
function
Further,
we
summarize
effects
bioactivities
LF,
future
perspectives
research.
Journal of Functional Foods,
Journal Year:
2022,
Volume and Issue:
89, P. 104932 - 104932
Published: Jan. 4, 2022
Native
and
chemically
modified
whey
proteins
their
peptide
derivatives
are
encountering
the
interest
of
nutraceutical
pharmaceutical
industries,
due
to
numerous
properties,
ranging
from
antimicrobial
immunological
antitumorigenic,
that
result
in
possibility
employ
milk
its
protein
components
a
wide
range
treatment
prevention
strategies.
Importantly,
were
found
exert
antiviral
actions
against
different
enveloped
non-enveloped
viruses.
Recently,
scientific
community
is
focusing
on
these
proteins,
especially
lactoferrin,
since
vitro
studies
have
demonstrated
they
an
important
activity
also
SARS-CoV-2.
Up-to
date,
several
investigating
efficacy
lactoferrin
other
vivo.
Aim
this
review
shed
light
most
relevant
findings
concerning
properties
potential
applications
human
health,
focussing
application
SARS-CoV-2
infection.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(5), P. 1418 - 1418
Published: May 6, 2023
In
recent
years,
small
extracellular
vesicles
(sEVs)
have
been
regarded
as
the
next
generation
of
novel
delivery
systems
after
lipid
nanoparticles
because
their
advantages
and
huge
prospects
in
drug
delivery.
Studies
shown
that
sEVs
are
abundant
milk
therefore
can
be
a
large
economical
source
sEVs.
Natural
milk-derived
(msEVs)
important
functions
such
immune
regulation,
anti-bacterial
infection,
anti-oxidative,
etc.,
play
beneficial
role
human
health
at
multiple
levels,
including
intestinal
health,
bone/muscle
metabolism,
microbiota
regulation.
addition,
they
pass
gastrointestinal
barrier
low
immunogenicity,
good
biocompatibility,
stability,
msEVs
considered
crucial
oral
vehicle.
Moreover,
further
engineered
for
targeted
to
prolong
circulation
time
or
enhance
local
concentrations.
However,
separation
purification,
complex
contents,
quality
control
hinder
application
This
paper
provides
comprehensive
review
biogenesis
characteristics,
isolation
composition,
loading
methods,
function
msEVs,
based
on
which
applications
biomedical
fields
explored.
Annals of Medicine and Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 4, 2024
Breastfeeding,
an
essential
aspect
of
infant
care,
has
garnered
recognition
beyond
its
immediate
health
benefits,
revealing
a
profound
and
lasting
impact
on
women’s
health.
Emerging
research
unveiled
compelling
relationship
between
breastfeeding
enduring
role
in
reducing
the
risk
ovarian
cancer.
This
narrative
review
aims
to
comprehensively
examine
lifelong
cancer
prevention,
transcending
infancy
delving
into
mechanisms
implications
for
Epidemiological
evidence
consistently
demonstrates
inverse
association
Prolonged
durations
correlate
with
significant
reduction
likelihood
developing
malignancies,
underscoring
protective
influence
sustained
lactation.
The
underlying
breastfeeding’s
prevention
involve
hormonal
modulation
cellular
changes.
Breastfeeding
contributes
reduced
ovulatory
cycles
estrogen
exposure,
mitigating
influences
linked
development.
Moreover,
alterations
induced
by
within
microenvironment
create
environment
less
conducive
malignant
transformations.
In
conclusion,
this
paper
consolidates
demonstrating
risk.
It
emphasizes
need
continued
research,
supportive
interventions,
societal
engagement
promote
practices.
Embracing
not
only
provides
benefits
but
also
represents
formidable
strategy
offering
promising
pathway
towards
enhanced
well-being.
GSC Advanced Research and Reviews,
Journal Year:
2024,
Volume and Issue:
19(1), P. 004 - 015
Published: April 7, 2024
This
review
examines
the
landscape
of
baby
food
product
management,
highlighting
diverse
nutritional
needs,
innovative
practices,
and
regulatory
challenges
encountered
by
companies
operating
in
Nigeria
United
States
(US).
As
essential
stakeholders
infant
health,
manufacturers
must
navigate
a
complex
terrain
shaped
cultural
preferences,
economic
factors,
governmental
regulations
to
meet
requirements
infants
young
children.
In
both
US,
needs
are
paramount,
with
an
increasing
emphasis
on
providing
balanced
diets
that
support
optimal
growth
development.
However,
specific
dietary
may
vary
between
regions
due
regional
agricultural
availability,
socio-economic
factors.
Understanding
catering
these
nuanced
is
critical
for
establish
trust
credibility
among
consumers.
Moreover,
innovations
management
play
crucial
role
addressing
evolving
consumer
demands
preferences.
From
organic
natural
ingredients
convenient
packaging
solutions,
continuously
striving
enhance
quality
convenience
products.
These
not
only
reflect
shifting
trends
but
also
serve
as
competitive
differentiator
crowded
market.
Nevertheless,
navigating
presents
significant
US.
Regulatory
frameworks
governing
safety,
labeling
requirements,
advertising
standards
subject
frequent
updates
modifications,
requiring
maintain
agility
compliance.
Additionally,
perceptions
surrounding
feeding
practices
influence
approaches,
further
complicating
market
entry
expansion
strategies.
underscores
importance
understanding
unique
embracing
products
By
adopting
comprehensive
approach
considers
market-specific
factors
global
best
can
effectively
markets
contribute
health
well-being
