Pharmaceuticals,
Journal Year:
2025,
Volume and Issue:
18(4), P. 502 - 502
Published: March 31, 2025
Background/Objectives:
Polysaccharides
are
complex
molecules
with
a
wide
range
of
biological
activities
that
can
be
used
in
various
biomedical
applications.
In
this
work,
the
antiulcer
effect
and
influence
on
level
pro-
anti-inflammatory
cytokines
Solanum
tuberosum
L.
polysaccharide
(STP)
were
studied.
Methods:
The
STP
was
studied
Okabe
chronic
peptic
ulcer
model
by
evaluating
index
Wistar
rats,
comparing
it
to
omeprazole
ranitidine.
Dose-effect
analysis
also
carried
out.
using
ELISA
kits.
Results:
After
treatment
groups,
healing
is
observed
60–80%
cases,
group
50%,
ranitidine
25%.
intravenous
injections
lead
formation
more
differentiated
mucous
membrane;
no
coarse
scar
tissue
formed,
which
typical
for
control
comparison
drugs.
Glycan
causes
significant
acceleration
experimental
ulcers
rats.
appears
modulate
cytokines.
On
fourth
tenth
days,
decrease
levels
pro-inflammatory
IL-1b
IFN-γ
noted
compared
group,
while
cytokine
IL-4
significantly
increased.
Conclusions:
Intravenous
administration
leads
restoration
functionality
effective
regeneration.
activity
based
regulation
balance.
Gut Microbes,
Journal Year:
2023,
Volume and Issue:
16(1)
Published: Dec. 27, 2023
The
human
gut
microbiota
constitutes
a
vast
and
complex
community
of
microorganisms.
myriad
microorganisms
present
in
the
intestinal
tract
exhibits
highly
intricate
interactions,
which
play
crucial
role
maintaining
stability
balance
microbial
ecosystem.
These
turn,
influence
overall
health
host.
mammalian
microbes
have
evolved
wide
range
mechanisms
to
suppress
or
even
eliminate
their
competitors
for
nutrients
space.
Simultaneously,
extensive
cooperative
interactions
exist
among
different
optimize
resource
utilization
enhance
own
fitness.
This
review
will
focus
on
competitive
members
discuss
key
modes
actions,
including
bacterial
secretion
systems,
bacteriocins,
membrane
vesicles
(MVs)
etc.
Additionally,
we
summarize
current
knowledge
often-overlooked
positive
within
microbiota,
showcase
representative
machineries.
information
serve
as
reference
better
understanding
occurring
environment.
Understanding
interaction
dynamics
competition
cooperation
is
unraveling
ecology
communities.
Targeted
interventions
aimed
at
modulating
these
may
offer
potential
therapeutic
strategies
disease
conditions.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(15), P. 8250 - 8250
Published: July 28, 2024
The
intricate
relationship
between
the
gastrointestinal
(GI)
microbiome
and
progression
of
chronic
non-communicable
diseases
underscores
significance
developing
strategies
to
modulate
GI
microbiota
for
promoting
human
health.
administration
probiotics
prebiotics
represents
a
good
strategy
that
enhances
population
beneficial
bacteria
in
intestinal
lumen
post-consumption,
which
has
positive
impact
on
In
addition,
dietary
fibers
serve
as
significant
energy
source
inhabiting
cecum
colon.
Research
articles
reviews
sourced
from
various
global
databases
were
systematically
analyzed
using
specific
phrases
keywords
investigate
these
relationships.
There
is
clear
association
fiber
intake
improved
colon
function,
gut
motility,
reduced
colorectal
cancer
(CRC)
risk.
Moreover,
state
health
reflected
reciprocal
bidirectional
relationships
among
food,
antioxidants,
inflammation,
body
composition.
They
are
known
their
antioxidant
properties
ability
inhibit
angiogenesis,
metastasis,
cell
proliferation.
Additionally,
they
promote
survival,
immune
inflammatory
responses,
inactivate
pro-carcinogens.
These
actions
collectively
contribute
role
prevention.
different
investigations,
supplements
containing
vitamins
have
been
shown
lower
risk
types.
contrast,
some
evidence
suggests
taking
can
increase
cancer.
Ultimately,
collaborative
efforts
immunologists,
clinicians,
nutritionists,
dietitians
imperative
designing
well-structured
nutritional
trials
corroborate
clinical
efficacy
therapy
managing
inflammation
preventing
carcinogenesis.
This
review
seeks
explore
interrelationships
fiber,
microbiome,
with
particular
focus
potential
implications
Foods,
Journal Year:
2023,
Volume and Issue:
12(16), P. 3083 - 3083
Published: Aug. 17, 2023
Due
to
today’s
fast-paced
lifestyle,
most
people
are
in
a
state
of
sub-health
and
face
“unexplained
fatigue”,
which
can
seriously
affect
their
health,
work
efficiency,
quality
life.
Fatigue
is
also
common
symptom
several
serious
diseases
such
as
Parkinson’s,
Alzheimer’s,
cancer,
etc.
However,
the
contributing
mechanisms
not
clear,
there
currently
no
official
recommendations
for
treatment
fatigue.
Some
dietary
polysaccharides
often
used
health
care
supplements;
these
have
been
reported
specific
anti-fatigue
effects,
with
minor
side
effects
rich
pharmacological
activities.
Dietary
be
activated
during
food
processing
or
gastrointestinal
transit,
exerting
unique
effects.
This
review
aims
comprehensively
summarize
evaluate
latest
advances
biological
processes
exercise-induced
fatigue,
understand
possible
molecular
alleviating
systematically
elaborate
roles
gut
microbiota
gut-muscle
axis
this
process.
From
perspective
axis,
investigating
relationship
between
fatigue
will
enhance
our
understanding
may
lead
significant
breakthrough
regarding
mechanism
paper
provide
new
perspectives
further
research
into
use
science
nutrition,
could
help
develop
potential
agents
open
up
novel
therapies
conditions.
