Immune Basis of Therapeutic Effects of Solanum tuberosum L. Polysaccharide on Chronic Peptic Ulcer Healing DOI Creative Commons
E. A. Generalov, Denis P. Laryushkin, Kristina A. Kritskaya

и другие.

Pharmaceuticals, Год журнала: 2025, Номер 18(4), С. 502 - 502

Опубликована: Март 31, 2025

Background/Objectives: Polysaccharides are complex molecules with a wide range of biological activities that can be used in various biomedical applications. In this work, the antiulcer effect and influence on level pro- anti-inflammatory cytokines Solanum tuberosum L. polysaccharide (STP) were studied. Methods: The STP was studied Okabe chronic peptic ulcer model by evaluating index Wistar rats, comparing it to omeprazole ranitidine. Dose-effect analysis also carried out. using ELISA kits. Results: After treatment groups, healing is observed 60–80% cases, group 50%, ranitidine 25%. intravenous injections lead formation more differentiated mucous membrane; no coarse scar tissue formed, which typical for control comparison drugs. Glycan causes significant acceleration experimental ulcers rats. appears modulate cytokines. On fourth tenth days, decrease levels pro-inflammatory IL-1b IFN-γ noted compared group, while cytokine IL-4 significantly increased. Conclusions: Intravenous administration leads restoration functionality effective regeneration. activity based regulation balance.

Язык: Английский

Interactions of non-starch polysaccharides with the gut microbiota and the effect of non-starch polysaccharides with different structures on the metabolism of the gut microbiota: A review DOI
Yujiao Sun, Jun Yao, Rui Gao

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 296, С. 139664 - 139664

Опубликована: Янв. 9, 2025

Язык: Английский

Процитировано

2

Microbial collaborations and conflicts: unraveling interactions in the gut ecosystem DOI Creative Commons
Shuang Wang,

Lingyi Mu,

Yu Chong

и другие.

Gut Microbes, Год журнала: 2023, Номер 16(1)

Опубликована: Дек. 27, 2023

The human gut microbiota constitutes a vast and complex community of microorganisms. myriad microorganisms present in the intestinal tract exhibits highly intricate interactions, which play crucial role maintaining stability balance microbial ecosystem. These turn, influence overall health host. mammalian microbes have evolved wide range mechanisms to suppress or even eliminate their competitors for nutrients space. Simultaneously, extensive cooperative interactions exist among different optimize resource utilization enhance own fitness. This review will focus on competitive members discuss key modes actions, including bacterial secretion systems, bacteriocins, membrane vesicles (MVs) etc. Additionally, we summarize current knowledge often-overlooked positive within microbiota, showcase representative machineries. information serve as reference better understanding occurring environment. Understanding interaction dynamics competition cooperation is unraveling ecology communities. Targeted interventions aimed at modulating these may offer potential therapeutic strategies disease conditions.

Язык: Английский

Процитировано

29

Gut microbiota modulation, prebiotic and bioactive characteristics of date pomace polysaccharides extracted by microwave-assisted deep eutectic solvent DOI
Gafar Babatunde Bamigbade, Athira Jayasree Subhash, Basel K. al-Ramadi

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 262, С. 130167 - 130167

Опубликована: Фев. 14, 2024

Язык: Английский

Процитировано

13

Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice DOI
Xinyi Cheng, Jinyan Chen, Xiaoquan Guo

и другие.

Environmental Pollution, Год журнала: 2024, Номер 343, С. 123232 - 123232

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

10

Interactions between Dietary Antioxidants, Dietary Fiber and the Gut Microbiome: Their Putative Role in Inflammation and Cancer DOI Open Access
Camelia Munteanu, Betty Schwartz

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(15), С. 8250 - 8250

Опубликована: Июль 28, 2024

The intricate relationship between the gastrointestinal (GI) microbiome and progression of chronic non-communicable diseases underscores significance developing strategies to modulate GI microbiota for promoting human health. administration probiotics prebiotics represents a good strategy that enhances population beneficial bacteria in intestinal lumen post-consumption, which has positive impact on In addition, dietary fibers serve as significant energy source inhabiting cecum colon. Research articles reviews sourced from various global databases were systematically analyzed using specific phrases keywords investigate these relationships. There is clear association fiber intake improved colon function, gut motility, reduced colorectal cancer (CRC) risk. Moreover, state health reflected reciprocal bidirectional relationships among food, antioxidants, inflammation, body composition. They are known their antioxidant properties ability inhibit angiogenesis, metastasis, cell proliferation. Additionally, they promote survival, immune inflammatory responses, inactivate pro-carcinogens. These actions collectively contribute role prevention. different investigations, supplements containing vitamins have been shown lower risk types. contrast, some evidence suggests taking can increase cancer. Ultimately, collaborative efforts immunologists, clinicians, nutritionists, dietitians imperative designing well-structured nutritional trials corroborate clinical efficacy therapy managing inflammation preventing carcinogenesis. This review seeks explore interrelationships fiber, microbiome, with particular focus potential implications

Язык: Английский

Процитировано

10

Chitosan and its derivatives: A novel approach to gut microbiota modulation and immune system enhancement DOI
Great Iruoghene Edo, Alice Njolke Mafe,

Ali B. M. Ali

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 289, С. 138633 - 138633

Опубликована: Дек. 13, 2024

Язык: Английский

Процитировано

9

Medicinal and edible polysaccharides from ancient plants: extraction, isolation, purification, structure, biological activity and market trends of sea buckthorn polysaccharides DOI
Xinmei Xu, Xianfeng Liu,

Shufu Yu

и другие.

Food & Function, Год журнала: 2024, Номер 15(9), С. 4703 - 4723

Опубликована: Янв. 1, 2024

Sea buckthorn ( Hippophae L.), a well-known medicinal and edible plant, is known as the “king of VC”.

Язык: Английский

Процитировано

8

A determination of the composition and structure of the polysaccharides fractions isolated from apple cell wall based on FT-IR and FT-Raman spectra supported by PCA analysis DOI
Monika Szymańska‐Chargot,

Patrycja Pękala,

Anna Siemińska‐Kuczer

и другие.

Food Hydrocolloids, Год журнала: 2023, Номер 150, С. 109688 - 109688

Опубликована: Дек. 25, 2023

Язык: Английский

Процитировано

21

Dietary Polysaccharides Exert Anti-Fatigue Functions via the Gut-Muscle Axis: Advances and Prospectives DOI Creative Commons
Yaping Zhou,

Zhongxing Chu,

Yi Luo

и другие.

Foods, Год журнала: 2023, Номер 12(16), С. 3083 - 3083

Опубликована: Авг. 17, 2023

Due to today’s fast-paced lifestyle, most people are in a state of sub-health and face “unexplained fatigue”, which can seriously affect their health, work efficiency, quality life. Fatigue is also common symptom several serious diseases such as Parkinson’s, Alzheimer’s, cancer, etc. However, the contributing mechanisms not clear, there currently no official recommendations for treatment fatigue. Some dietary polysaccharides often used health care supplements; these have been reported specific anti-fatigue effects, with minor side effects rich pharmacological activities. Dietary be activated during food processing or gastrointestinal transit, exerting unique effects. This review aims comprehensively summarize evaluate latest advances biological processes exercise-induced fatigue, understand possible molecular alleviating systematically elaborate roles gut microbiota gut-muscle axis this process. From perspective axis, investigating relationship between fatigue will enhance our understanding may lead significant breakthrough regarding mechanism paper provide new perspectives further research into use science nutrition, could help develop potential agents open up novel therapies conditions.

Язык: Английский

Процитировано

18

Along the microbiota–gut–brain axis: Use of plant polysaccharides to improve mental disorders DOI
Jiayu Gao, Ying Liang, Pu Liu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 265, С. 130903 - 130903

Опубликована: Март 19, 2024

Язык: Английский

Процитировано

6