Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(22), P. 6874 - 6874
Published: Nov. 15, 2024
Psoriasis is a chronic inflammatory skin disease with complex pathogenesis and variable severity. Performed studies have indicated the impact of vitamin D3 deficiency on psoriasis its However, there no clear evidence influence mucosal microbiome onset progression psoriasis. This review aims to present current role colonization oral mucosa by
Language: Английский
Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1603 - 1603
Published: May 7, 2025
Rheumatic diseases such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic (PsA) are chronic autoimmune disorders characterized by persistent inflammation oxidative stress, leading to joint damage reduced quality of life. In recent years, increasing attention has been given diet a modifiable environmental factor that can complement pharmacological therapy. This review summarizes current evidence on how key dietary components—such omega-3 fatty acids, fiber, polyphenols, antioxidant vitamins—affect inflammatory pathways balance. Special emphasis is placed the Mediterranean diet, low-starch diets, hypocaloric regimens, which have shown potential in improving disease activity. The gut microbiota emerges critical mediator between immune function, with interventions capable restoring eubiosis strengthening intestinal barrier. Additionally, this paper discusses challenges clinical implementation therapy, need for personalized nutritional strategies, importance integrating into holistic patient care. Collectively, findings suggest may reduce activity, mitigate systemic inflammation, enhance patients’ overall well-being.
Language: Английский
Citations
0
BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)
Published: July 18, 2024
Abstract Background Many effective therapies for psoriasis are being applied in clinical practice recent years, however, some patients still can’t achieve satisfied effect even with biologics. Therefore, it is crucial to identify factors associated the treatment efficacy among patients. This study aims explore influencing of based on decision tree model and logistic regression. Methods We implemented an observational recruited 512 Shanghai Skin Diseases Hospital from 2021 2022. used face-to-face questionnaire interview physical examination collect data. Influencing were analyzed by using regression, CART algorithm. The receiver operator curve (ROC) was plotted evaluation statistical significance set at P < 0.05. Results predominately males (72.1%), a median age 47.5 years. In this study, 245 achieved ≥ 75% improvement area severity index (PASI) score week 8 identified as success (47.9%). Logistic regression analysis showed that senior high school above, without family history, tobacco smoking alcohol drinking had higher percentage psoriasis. final contained four layers total seventeen nodes. Nine classification rules extracted five screened, which indicated most critical variable prediction. Model ROC under (AUC) 0.79 (95%CI: 0.75 ~ 0.83) both (0.80 sensitivity 0.69 specificity) (0.77 0.73 specificity). Conclusion Psoriasis education, smoking, history better efficacy. Decision similar predicting model, but feasibility due nature simple, intuitive, easy understand.
Language: Английский
Citations
3
Actas Dermo-Sifiliográficas, Journal Year: 2023, Volume and Issue: 115(4), P. 374 - 386
Published: Oct. 25, 2023
Numerous diets for losing weight, building strength, and managing a range of cardiovascular, neurologic, skin diseases have become popular in recent years. The ketogenic diet intermittent fasting particular shown promising results clinical sports medicine. Mediterranean diet, turn, is widely recognized its numerous health benefits. Also are the paleo vegan gluten-free diets. Positive effects on inflammatory conditions, such as psoriasis, atopic dermatitis, hidradenitis suppurativa, acne, been observed patients who practice or follow This last choice may also protect against certain cancers. We review role several management disorders. Se han popularizado diversas dietas para perder peso, incrementar la capacidad física y el manejo de múltiples patologías crónicas: cardiovasculares, neurológicas o cutáneas. Destacan dieta cetogénica ayuno intermitente, con resultados prometedores en medicina tradicional deportiva. Además, mediterránea se ha consolidado como una forma alimentación impacto positivo muy significativo salud. Otras populares son "paleo", vegana libre gluten. La cetogénica, intermitente aportan favorables dermatosis inflamatorias dermatitis atópica, supurativa y/o acné. podría actuar también factor protector desarrollo algunas neoplasias En este artículo presentamos revisión del rol dermatosis.
Citations
5
Actas Dermo-Sifiliográficas, Journal Year: 2024, Volume and Issue: 115(4), P. T374 - T386
Published: Feb. 7, 2024
Numerous diets for losing weight, building strength, and managing a range of cardiovascular, neurologic, skin diseases have become popular in recent years. The ketogenic diet intermittent fasting particular shown promising results clinical sports medicine. Mediterranean diet, turn, is widely recognized its numerous health benefits. Also are the paleo vegan gluten-free diets. Positive effects on inflammatory conditions, such as psoriasis, atopic dermatitis, hidradenitis suppurativa, acne, been observed patients who practice or follow This last choice may also protect against certain cancers. We review role several management disorders.
Language: Английский
Citations
1
Clinical and Experimental Dermatology, Journal Year: 2024, Volume and Issue: unknown
Published: March 28, 2024
Abstract Background It is unknown if an unhealthy diet can affect the risk of developing psoriasis. Objectives To test hypothesis that individuals with have increased prevalent and incident Methods We included 105 332 adults from Copenhagen General Population Study, who were invited to participate between 2003 2015. The response rate was 43%. An vs. healthy defined according adherence general national dietary guidelines. participants grouped into three groups: low, intermediate high guidelines; this based on information a food frequency questionnaire. Identification psoriasis made using International Classification Diseases codes. Results Of individuals, 580 had diagnosis at time enrolment 640 received during median follow-up 9 years. Risk nonadherence guidelines in stepwise manner age- sex-adjusted odds ratio 1.70 (95% confidence interval 1.26–2.30) low similar multivariable-adjusted model. Prospective analyses adjusted for age sex showed weak association (P trend 0.04). This disappeared, when adjusting multiple confounders 0.50). Conclusions Although unhealthier diet, alone does not appear independently increase
Language: Английский
Citations
1
Food Bioscience, Journal Year: 2024, Volume and Issue: 59, P. 104144 - 104144
Published: April 18, 2024
Language: Английский
Citations
1
British Journal of Dermatology, Journal Year: 2024, Volume and Issue: 191(6), P. 897 - 905
Published: June 24, 2024
Abstract Background Psoriatic disease (PsD) is closely associated with cardiovascular (CV) disease. The Life’s Essential 8 (LE8) score a new metric to assess CV health (CVH), where higher indicates better CVH. However, the longitudinal association between LE8 and risk of PsD remains uncertain. Objectives To investigate, in cohort study, score, genetic susceptibility PsD. Methods This study included 261 642 participants UK Biobank without at baseline. comprises eight indicators: diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, glucose pressure. Cox proportional hazard models were used examine participants’ scores, Hazard ratios (HRs) 95% confidence intervals (CIs) calculated. Results During an average follow-up 12.3 years, 1501 developed Compared low HRs developing for those moderate high scores 0.51 (95% CI 0.43–0.59) 0.34 0.27–0.42) after adjustments, respectively. Dose–response analysis revealed linear negative continuous (P < 0.001), no evidence nonlinear detected. Genetic did not modify this (Pinteraction = 0.63). Subgroup analyses that women had more pronounced beneficial 0.02). Conclusions Our suggests regardless risk, lower PsD, particularly women. Consequently, maintaining good CVH status recommended prevent risks.
Language: Английский
Citations
1
IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Feb. 14, 2024
The term “exposome” encompasses all the environmental elements, both infectious and non-infectious, that an individual encounters throughout life. It refers to collective exposure various factors in environment can have impact on human health finally result a disease or affect course. exposome is implicated skin diseases including psoriasis. Ranging from lifestyle habits such as diet, smoking, obesity, sunlight exposure, pre-existing diseases, agents’ patients’ unique features microbes, oxidative stress parameters, chemical environment, cutaneous immune reactions, seems encounter variety of different exposures. All these exposures turn contribute distinct ways pathogenesis pathways creation psoriatic lesions shape course progression. Also, interaction between genetic well-established contributor. This chapter discusses link each aspect psoriasis mechanisms well treatment plans taking into consideration factors. Understanding exposome–psoriasis relationship would lead implications targeted interventions mitigate possible risk give future directions.
Language: Английский
Citations
1
Nutrients, Journal Year: 2023, Volume and Issue: 15(21), P. 4563 - 4563
Published: Oct. 27, 2023
Fatigue and musculoskeletal pain are also frequent in patients with psoriasis (PsO) without arthritis (PsA). The current study aimed to assess the impact of an intervention program based on aerobic training reduce fatigue PsO PsA. A total 118 male volunteered interventional were randomly allocated experimental (n = 59) or control group 59). consisted a 16-week treadmill, three sessions per week, consisting warm-up, 35-50 min treadmill exercise (increasing 5 min/4 weeks) at work intensity 50-65% peak heart-rate 5%/4 weeks), cooling-down. functional assessment chronic illness therapy scale (FACIT-Fatigue), health questionnaire disability index (HAQ-DI), visual analog (VAS) compared pre post intervention. Nutritional intake, maximal power, lipid profile, serum markers muscle damage, body composition assessed. When baseline, FACIT-Fatigue, HAQ-DI, VAS scores significantly improved increasing damage. Fat mass percentage, oxygen consumption improved. In conclusion, moderate was safe, well tolerated, effective psoriatic Long-term follow-up studies required examine whether these promising results may improve clinical outcomes.
Language: Английский
Citations
3
Cutis, Journal Year: 2024, Volume and Issue: 113(2)
Published: Feb. 1, 2024
Language: Английский
Citations
0