Preparation, structural characterization, biological activity, and nutritional applications of oligosaccharides

Food Chemistry X, Journal Year: 2024, Volume and Issue: 22, P. 101289 - 101289

Published: March 15, 2024

Oligosaccharides are low-molecular-weight carbohydrates between monosaccharides and polysaccharides. They can be extracted directly from natural products by physicochemical methods or obtained chemical synthesis enzymatic reaction. have important physiological properties. Their research production involve many disciplines such as medicine, industry, biology. Functional oligosaccharides, an excellent functional food base, used dietary fibrer prebiotics to enrich the diet; improve microecology of gut; exert antitumour, anti-inflammatory, antioxidant, lipid-lowering Therefore, industrial applications oligosaccharides increased rapidly in past few years. It has great prospects field medicinal chemistry. This review summarized preparation, structural features biological activities with particular emphasis on application industry human nutritional health. aims inform further development

Language: Английский

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House cricket (Acheta domesticus): A review based on its nutritional composition, quality, and potential uses in the food industry

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 142, P. 104226 - 104226

Published: Nov. 7, 2023

Language: Английский

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Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care—clinically relevant 3PM innovation

The EPMA Journal, Journal Year: 2024, Volume and Issue: 15(2), P. 163 - 205

Published: April 18, 2024

Despite their subordination in humans, to a great extent, mitochondria maintain independent status but tightly cooperate with the "host" on protecting joint life quality and minimizing health risks. Under oxidative stress conditions, healthy promptly increase mitophagy level remove damaged "fellows" rejuvenating mitochondrial population sending fragments of mtDNA as SOS signals all systems human body. As long metabolic pathways are under systemic control well-concerted together, adaptive mechanisms become triggered increasing protection, activating antioxidant defense repair machinery. Contextually, attributes patho-/physiology instrumental for predictive medical approach cost-effective treatments tailored individualized patient profiles primary (to protect vulnerable individuals again health-to-disease transition) secondary affected disease progression) care. Nutraceuticals naturally occurring bioactive compounds demonstrating health-promoting, illness-preventing, other health-related benefits. Keeping mind health-promoting properties nutraceuticals along therapeutic potential safety profile, there is permanently growing demand application mitochondria-relevant nutraceuticals. Application beneficial only if meeting needs at individual level. Therefore, risk assessment creation pivotal importance followed by adapted nutraceutical sets needs. Based scientific evidence available nutraceuticals, this article presents examples frequent which require protective measures targeted holistic following advanced concepts predictive, preventive, personalized medicine (PPPM/3PM)

Language: Английский

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Intracellular Protective Functions and Therapeutical Potential of Trehalose

Molecules, Journal Year: 2024, Volume and Issue: 29(9), P. 2088 - 2088

Published: May 1, 2024

Trehalose is a naturally occurring, non-reducing saccharide widely distributed in nature. Over the years, research on trehalose has revealed that this initially thought simple storage molecule multifunctional and multitasking compound protecting cells against various stress factors. This review presents data role of maintaining cellular homeostasis under conditions virulence bacteria fungi. Numerous studies have demonstrated acts cell as an osmoprotectant, chemical chaperone, free radical scavenger, carbon source, factor, metabolic regulator. The increasingly researched medical therapeutic applications are also discussed.

Language: Английский

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Direct hybridization and bioinformatics analysis of circulating microRNAs in patients with Alzheimer’s disease under intravenous trehalose treatment

Brain Research, Journal Year: 2025, Volume and Issue: unknown, P. 149607 - 149607

Published: April 1, 2025

Language: Английский

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The mechanism of polysaccharide synthesis of Sanghuangporus sanghuang based on multi-omic analyses and feedback inhibition

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 321, P. 121288 - 121288

Published: Aug. 11, 2023

Language: Английский

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Dehydrated mycelia (Cordyceps militaris, Grifola frondosa, Hericium erinaceus and Laricifomes officinalis) as Novel Foods: A comprehensive NMR study

LWT, Journal Year: 2024, Volume and Issue: 199, P. 116123 - 116123

Published: April 30, 2024

Several medicinal mushrooms have been approved as European Novel Foods or the potential to become Foods. However, their chemical characterization is limited, being mainly focused on specific compounds. Here, dehydrated mycelia (isolated from sporophores collected in Italy) of Grifola frondosa, Hericium erinaceus, recently defined Foods, and Cordyceps militaris Laricifomes officinalis, with Food use, were analyzed by NMR methodology define metabolite nutritional profile. Amino acids derivatives, sugars polyols, organic acids, fatty lipid polar moieties, nitrogen-containing compounds identified quantified hydroalcoholic extracts. C. showed a high amount glutamate, citrate mannitol, also involved mushroom taste, only species presenting tri-unsaturated acids. L. officinalis was characterized highest TAA EAA, lowest polyols content. G. frondosa H. erinaceus amounts trehalose (13-14 % dried weight). Each potentially represents an innovative food matrix alone, for culinary, nutraceutical needs, mixed together obtain new products. Moreover, these can be interest sources isolated bioactive supplements particular functions.

Language: Английский

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A comprehensive review on natural sweeteners: impact on sensory properties, food structure, and new frontiers for their application

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: Aug. 17, 2024

In recent years, the worldwide increase in lifestyle diseases and metabolic disorders has been ascribed to excessive consumption of sucrose added sugars. For this reason, many approaches have developed order replace food beverage formulations with alternative sweetening compounds. The raising awareness concerning synthetic sweeteners due their negative impact on health, triggered need search for substances. Natural may be classified in: (i) non-nutritive (e.g., neohesperidine dihydrochalcone, thaumatin, glycyrrhizin mogroside stevia) (ii) bulk sweeteners, including both polyols maltitol, mannitol, erythritol) rare sugars tagatose allulose). review we discuss most popular natural application main sectors bakery, dairy, confectionary beverage), providing a full understanding textural sensory properties comparison sucrose. Furthermore, analyze use blends, which addition enabling an effective replacement sugar, complement merits limits individual Finally, microencapsulation technology is presented as strategy solving some issues such aftertaste, bitterness, unpleasant flavors, but also enhance stability ease use.

Language: Английский

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Exploring the dual role of anti-nutritional factors in soybeans: a comprehensive analysis of health risks and benefits

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 18

Published: Nov. 19, 2024

Soybeans (Glycine max [L.] Merr.) are a globally significant crop, valued for their high protein content and nutritional versatility. However, they contain anti-nutritional factors (ANFs) that can interfere with nutrient absorption pose health risks. This comprehensive review examines the presence impact of key ANFs in soybeans, such as trypsin inhibitors, lectins, oxalates, phytates, tannins, soybean polysaccharides, based on recent literature. The physiological roles, potential hazards ANFs, detailed balance between harmful beneficial effects human health, well efficacy deactivation or removal techniques food processing, were discussed. findings highlight dual nature soybeans. Some have been found to offer benefits include acting antioxidants, potentially reducing risk cancer, exhibiting anti-inflammatory effects. it is important note same also negative impacts. For instance, tannins may lead gastrointestinal discomfort contribute mineral deficiencies when consumed excess without proper processing. will provide clear understanding role soybean-based diets inform future research processing strategies.

Language: Английский

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Fecal fermentation of lentinan and its effect on gut microbiota and metabolites

International Journal of Food Science & Technology, Journal Year: 2025, Volume and Issue: 60(1)

Published: Jan. 1, 2025

Abstract Lentinan (LNT) is a polysaccharide from Shiitake mushrooms that has significant effects regarding antioxidant, hypoglycemic, anti-inflammatory activities, etc., and this effect influenced by the human intestinal flora. However, interactions between LNT microorganisms, their metabolic processes, remain unclear. In study, fermentation characteristics of its on flora metabolites were studied in vitro fermentation. Our results indicated was effectively utilised microbiota, utilisation rate 62.7 ± 3.0% after for 48 hr. The concentrations short-chain fatty acids (mainly acetic acid propionic acid) increased to 4.157 0.197 5.847 0.283 mM, respectively. also relative abundance beneficial bacteria, such as Bifidobacterium Parabacteroides, while reducing harmful bacteria like Veillonella Klebsiella. Metabolomics microbial correlation analysis revealed catabolism accompanied amino catabolism, especially alanine, aspartic acid, glutamate, biosynthesis adenosine 5’-monophosphate, etc. These findings suggest can support gut health demonstrates potential prebiotic.

Language: Английский

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