Revue française d'allergologie, Journal Year: 2024, Volume and Issue: 65(1), P. 104197 - 104197
Published: Dec. 2, 2024
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131698 - 131698
Published: April 18, 2024
Language: Английский
Citations
9
Nutrients, Journal Year: 2024, Volume and Issue: 16(22), P. 3891 - 3891
Published: Nov. 14, 2024
Breastfeeding is globally recognized as the optimal method of infant nutrition, offering health benefits for both child and mother, making it a public priority. However, potential advantages breastfeeding extend well beyond initial months. Breast milk adapts to evolving needs growing infant, its immunological, microbiological, biochemical properties have been associated with enhanced protection against infections chronic diseases, improved growth development, lower rates hospitalization mortality. This review explores evidence supporting continuation six More meticulous studies employing consistent methodologies addressing confounders are essential. will enable more accurate determination extent mechanisms positive impact prolonged allow implementation effective strategies.
Language: Английский
Citations
5
iScience, Journal Year: 2024, Volume and Issue: 27(10), P. 110902 - 110902
Published: Sept. 12, 2024
Studies have shown that breastfeeding can reduce the risk and severity of inflammatory bowel disease (IBD) in children adults. Probiotics breast milk also been isolated their effects on IBD studied. However, based current evidence, exact efficacy mechanisms probiotics treatment cannot be determined. In this study,
Language: Английский
Citations
4
Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 104893 - 104893
Published: Jan. 1, 2025
Language: Английский
Citations
0
Frontiers in Environmental Health, Journal Year: 2024, Volume and Issue: 3
Published: Sept. 20, 2024
This systematic literature review investigates the relationship between air pollution exposure and inflammatory bowel disease (IBD), encompassing Crohn's (CD) ulcerative colitis (UC). Despite growing concern over pollution's impact on various health outcomes, studies specifically addressing effects digestive system, particularly IBD, are relatively rare. aims to synthesize current knowledge this topic, focusing mechanisms underlying these associations role of different pollutants. Following PRISMA guidelines, a search PubMed Web Science databases was conducted, yielding 13 epidemiological six mechanistic (toxicological) meeting inclusion criteria. The examined IBD pollutants, including PM 2.5 (particles with an aerodynamic diameter smaller than, or equal to, µm), 10 2.5–10 (coarse particles in range BC (black carbon), NO 2 (nitrogen dioxide), monoxide), x oxides), N O (nitrous oxide), CO (carbon SO (sulfur VOC (volatile organic compounds), 3 (ozone), (oxidant capacity), traffic load. Study methodologies varied among studies, four cohort two ecological three case-control using two-sample Mendelian randomization, longitudinal time-series studies. Eight investigated separately, while five analyzed as whole without distinguishing CD UC. Eleven found statistically significant although inconsistent results were several A total number retrieved. Among particulate matter metric, one based metrics. With combination animal, human, vitro terms biological indicate that influences composition gut microbiome, altering metabolic functions within gut, creates immunological reactions inflammation contributing development IBD. Consequently, suggest link both onset exacerbation However, differences study design, assessment, pollutant types make it challenging draw any firm conclusions. Moreover, lack multi-pollutant models most makes difficult estimate individual effect specific highlights need for further research utilizing robust designs standardized assessment methods better understand By elucidating associations, policymakers healthcare professionals can develop effective strategies mitigate adverse health.
Language: Английский
Citations
0
Microorganisms, Journal Year: 2024, Volume and Issue: 12(10), P. 1977 - 1977
Published: Sept. 30, 2024
The prevalence of pediatric inflammatory bowel disease (pIBD) has been increasing over the last two decades. Yet, treatment strategies are still limited, in part due to multifactorial nature and complex interplay between genetic, environmental, dietary, immune, gut microbial factors its etiology. With their direct indirect anti-inflammatory properties, human milk oligosaccharides (HMOs) a promising management strategy for IBD. However, date there no insights into how HMOs may affect pIBD microbiota. Here, we compared effects 2'fucosyllactose (2'FL), difucosyllactose (DFL), 3'sialyllactose (3'SL), blends thereof with fructooligosaccharide (FOS) on microbiota functionality (short- branched-chain fatty acids, pH, gas production) composition (quantitative shallow shotgun sequencing) using fecal material from eight different Crohn's patients inoculated SIFR
Language: Английский
Citations
0
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2024, Volume and Issue: 16(5)
Published: Sept. 1, 2024
ABSTRACT Inflammatory bowel disease (IBD) is a complex and recurring inflammatory disorder that affects the gastrointestinal tract influenced by genetic predisposition, immune dysregulation, gut microbiota, environmental factors. Advanced therapies, such as biologics small molecules, target diverse pathways to manage IBD. Nanoparticle (NP)‐based drugs have emerged effective tools, offering controlled drug release targeted delivery. This review highlights NP modifications for anti‐inflammatory purposes, utilizing changes those in size, charge, redox reactions, ligand–receptor interactions delivery systems. By using pathological microenvironmental cues guide design, precise targeting can be achieved. In IBD, crucial aspect of intervention specific types cells, epithelial address compromised intestinal barrier function reduce overactive responses. also addresses current challenges future prospects, with goal advancing development NP‐mediated strategies IBD treatment.
Language: Английский
Citations
0
Revue française d'allergologie, Journal Year: 2024, Volume and Issue: 65(1), P. 104197 - 104197
Published: Dec. 2, 2024
Citations
0