Depression and Accelerated Aging: The Eveningness Chronotype and Low Adherence to the Mediterranean Diet Are Associated with Depressive Symptoms in Older Subjects DOI Open Access
José V. Sorlí,

Edurne de la Cámara,

Rebeca Fernández-Carrión

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 17(1), P. 104 - 104

Published: Dec. 30, 2024

Background and objectives: Depression often results in premature aging, which increases the risk of other chronic diseases, but very few studies have analyzed association between epigenetic biomarkers aging depressive symptoms. Similarly, limited research has examined joint effects adherence to Mediterranean diet (MedDiet) chronotype on symptoms, accounting for sex differences. Therefore, these are objectives our investigation a population at high cardiovascular risk. Methods: We 465 older subjects (aged 55–75) with metabolic syndrome assessed symptoms by Beck Inventory (BDI-II). MedDiet was measured 17-item score, Morningness–Eveningness Questionnaire (MEQ). Blood DNA methylation analyzed, epigenomic age acceleration were determined. focused Dunedin Pace Aging Computed from Epigenome (DunedinPACE). fitted multivariable models interaction terms. Results: Prevalence depression statistically higher women (p < 0.001). strongly inversely associated whole 0.01), while MEQ score 0.05). In analysis, both remained BDI-II 0.05), showing additive effects. No observed. women, significantly faster (measured DunedinPACE biomarker). This significant even after adjustment chronotype. Conclusions: syndrome, eveningness greater could potentially counteract Women showed stronger associations, importantly, we reported first time this that accelerated aging.

Language: Английский

Anxiety disorders and the gut microbiota: a bibliometric and visual analysis DOI Creative Commons

Linli Guo,

Qin Ding, Qing Li

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 20, 2025

Introduction Anxiety disorder is a common mental illness, yet its specific mechanisms remain unclear. Recent research has revealed connection between gut microbiota and anxiety disorders. This study aims to assess the current global landscape, highlight topics of interest, explore future directions in field disorders microbiota. Methods We extracted review articles related from Web Science, covering period 2004 2023. used VOSviewer 1.6.18.0, Scimago Graphica, CiteSpace 6.2. R2 visualize contributions countries, institutions, journals, authors, citations, keywords this field. Result A total 1198 were included bibliometric analysis. Over past two decades, both publications citations have shown steady increase. China, United States, Canada top three countries terms publication output. John Cryan University College Cork had highest number citation impact area research. The journal Nutrients publications, while Brain Behavior Immunity most citations. Key themes recent years anxiety, microbiota, depression, stress, gut-brain axis, probiotics, all which are likely be important directions. Conclusion analysis key areas emerging trends, including risk factors, stressors, inflammatory responses, probiotics. These insights can guide researchers towards more comprehensive understanding advancements field, help shape facilitate identification new therapeutic targets for disorder, ultimately improving clinical outcomes.

Language: Английский

Citations

1
The burden of chronic anxiety and depression symptomatology on 20-year cardiovascular disease incidence: The ATTICA study (2002–2022) DOI
Vasiliki C. Baourda, Christina Chrysohoou, Fotios Barkas

et al.

Personalized Medicine in Psychiatry, Journal Year: 2025, Volume and Issue: 49-50, P. 100150 - 100150

Published: Feb. 27, 2025

Language: Английский

Citations

0
Impact of DASH and mediterranean diets on mood and happiness in young adult males: a cross-sectional study DOI Creative Commons
Shervin Kazeminejad, Mitra Abtahi, Mohammadreza Askari

et al.

BMC Research Notes, Journal Year: 2025, Volume and Issue: 18(1)

Published: March 6, 2025

The association between the Mediterranean diet (MED) and dietary approach to stop hypertension (DASH) with some mental disorders is well-documented. However, a consistent relationship young adults as vulnerable population has yet be known. Therefore, we aimed investigate relation Iranian male adults' mood happiness state DASH/MED patterns. Participants' mean age was 23.65 ± 1.74 years, within range of 18-28 their BMI 24.23 3.82 kg/m². After adjusting for all covariates, those in highest DASH tertile had 54% lower odds poor compared lowest (OR = 0.46; 95%CI: 0.24, 0.88). An inverse also found low scores T3 vs. T1 0.51, 0.27, 0.96). No significant MED or happiness. results showed that participants who adhered more closely were less likely report being unhappy having mood. Further prospective studies are required confirm these findings.

Language: Английский

Citations

0
Promoting a healthy diet for chronic disease prevention and environmental sustainability DOI
Sandra Boatemaa Kushitor,

Deborah Esaa Larbi-Sarpong,

J William

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
The Gut Microbiome in Anxiety Disorders DOI Creative Commons
Mary I. Butler, Sarah Kittel‐Schneider, Jolana Wagner‐Skacel

et al.

Current Psychiatry Reports, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

We aim to update readers on the latest evidence regarding role of gut microbiome in generalized anxiety disorder (GAD), panic (PD), agoraphobia, and social (SAD). This review summarises literature composition function these conditions, provides insights about causality mechanisms evaluates current for microbiome-based interventions disorders. Most studies exploring disorders are small, cross-sectional studies. Nevertheless, some consistent findings emerge. Bacterial taxa such as Eubacterium, Coprococcus Faecalibacterium may be depleted GAD. Studies PD SAD scarce and, our knowledge, there have been no conducted agoraphobia. Probiotics help reduce symptoms, although majority non-clinical cohorts. Large, prospective required further elucidate microbiome-gut-brain axis Microbiome-based hold promise, but randomised controlled trials clinical populations with relevant diagnoses now warranted urgently required.

Language: Английский

Citations

0
Adherence to a Mediterranean diet and leisure-time physical activity are associated with reduced initiation of antidepressant, anxiolytic, antipsychotic and antiseizure drug use in older adults: a cohort study DOI Creative Commons
Marta Hernández,

Eleonora Fornara,

Camille Lassale

et al.

Age and Ageing, Journal Year: 2025, Volume and Issue: 54(4)

Published: March 28, 2025

We explored how adherence to the Mediterranean diet (MedDiet) and leisure-time physical activity (LTPA) impact psychoactive medication use in older adults. assessed cumulative MedDiet LTPA's on mental health initiation individuals at high risk of chronic disease. Associations between average (per one-point increase score) LTPA 20 metabolic equivalents task-minute/day [METs-min/day]) with drug were by multivariable Cox regressions. non-linear exposure-outcome associations using smoothed cubic splines multiplicative interaction LTPA. A total 5940-6896 participants (mean age 67, 58% women) over 4.2-4.7 years, each point decreased antidepressants 23-28% (HR 0.72, 95% CI 0.67-0.77), anxiolytics 0.75, 0.70-0.81), antipsychotics 0.77, 0.65-0.91), antiseizures 0.69-0.85). for strong low levels. Relationships linear lowest values (0-150 METs-min/day); every METs-min/day increases associated 20% lower initiating 0.80, 0.75-0.86) 15% less 0.85, 0.79-0.90). Association was (+20 METs-min/day: HR 0.96, 0.94-0.99), no found antipsychotics. High (≥10) (≥150 METs-min/day) reduced 42%-59%. Combination additive antidepressants, synergistic anxiolytics. drugs

Language: Английский

Citations

0
Adherence to the Mediterranean Diet and Cardiovascular Risk Factors among the Lebanese Population: A Nationwide Cross-Sectional Post Hoc Study DOI Open Access
Rony M. Zeenny, Chadia Haddad, Aline Hajj

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(15), P. 2426 - 2426

Published: July 26, 2024

Objective: This study aims to identify the association between adherence healthy eating, using Lebanese Mediterranean Diet Scale (LMDS), and cardiovascular risk factors in population. Materials Methods: A cross-sectional a multistage cluster sample was conducted Lebanon. Sociodemographic characteristics were collected through structured interviews self-administered questionnaires. The LMDS assessed dietary habits. associations diabetes, dyslipidemia, disease investigated stratification analysis. Results: included 2048 people (mean age: 41.54 ± 17.09 years). Higher diet associated with older age (Beta = 0.175, p < 0.001), being female 0.085, married 0.054, 0.047), participating regular physical activity 0.142, having 0.115, 0.001) diabetes 0.055, 0.043). Adherence was, however, negatively smoker −0.083, 0.002), previous −0.059, 0.026), higher distress levels −0.079, 0.002). Stratification analysis by (CVD) consistently demonstrated these associations. Conclusions: These findings suggest that demographic health influence population’s diet. Older age, gender, status, activity, CVD, all found be In contrast, smoking inversely it.

Language: Английский

Citations

2
Editorial for the Special Issue: Geriatric Nursing Nutrition DOI Open Access
Edda Cava, Mauro Lombardo

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4420 - 4420

Published: Dec. 23, 2024

Malnutrition, a significant risk factor for mortality and morbidity in the elderly, poses huge threat geriatric population, showing high prevalence, especially people affected by chronic non-communicable age-related diseases [...]

Language: Английский

Citations

0
Depression and Accelerated Aging: The Eveningness Chronotype and Low Adherence to the Mediterranean Diet Are Associated with Depressive Symptoms in Older Subjects DOI Open Access
José V. Sorlí,

Edurne de la Cámara,

Rebeca Fernández-Carrión

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 17(1), P. 104 - 104

Published: Dec. 30, 2024

Background and objectives: Depression often results in premature aging, which increases the risk of other chronic diseases, but very few studies have analyzed association between epigenetic biomarkers aging depressive symptoms. Similarly, limited research has examined joint effects adherence to Mediterranean diet (MedDiet) chronotype on symptoms, accounting for sex differences. Therefore, these are objectives our investigation a population at high cardiovascular risk. Methods: We 465 older subjects (aged 55–75) with metabolic syndrome assessed symptoms by Beck Inventory (BDI-II). MedDiet was measured 17-item score, Morningness–Eveningness Questionnaire (MEQ). Blood DNA methylation analyzed, epigenomic age acceleration were determined. focused Dunedin Pace Aging Computed from Epigenome (DunedinPACE). fitted multivariable models interaction terms. Results: Prevalence depression statistically higher women (p < 0.001). strongly inversely associated whole 0.01), while MEQ score 0.05). In analysis, both remained BDI-II 0.05), showing additive effects. No observed. women, significantly faster (measured DunedinPACE biomarker). This significant even after adjustment chronotype. Conclusions: syndrome, eveningness greater could potentially counteract Women showed stronger associations, importantly, we reported first time this that accelerated aging.

Language: Английский

Citations

0