Impact of Lactocaseibacillus (Lactobacillus) paracasei sup. paracasei TISTR 2593 Probiotic Supplementation on the Gut Microbiome of Hypercholesterolemia Patients: A Randomized Controlled Trial DOI Open Access

Kamonsri Nuankham,

Jaruwan Sitdhipol, Pennapa Chonpathompikunlert

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 2916 - 2916

Published: Sept. 1, 2024

Probiotics have shown potential in managing hypercholesterolemia and related metabolic conditions. This study evaluated the effects of Lactocaseibacillus (Lactobacillus) paracasei sup. TISTR 2593 on gut microbiome health patients with hypercholesterolemia, was registered Thai Clinical Trial Registry (TCTR 20220917002). In a randomized, double-blind, placebo-controlled trial, 22 hypercholesterolemic participants received either probiotic or placebo daily for 90 days. Fecal samples collected before after intervention revealed significant changes, including decrease Subdoligranulum, linked to rheumatoid arthritis, an increase Flavonifractor, known its anti-inflammatory properties. Additionally, group exhibited reduction low-density lipoprotein cholesterol (LDL-C) levels. These findings suggest that L. can modulate improve health, warranting further investigation into mechanisms long-term benefits.

Language: Английский

Insights of probiotics as an alternative medicine for cancer therapy, mechanism, and applications DOI Creative Commons

Sourik Mukherjee,

Dharmender Kumar, Dipanjan Guha

et al.

Medicine in Microecology, Journal Year: 2024, Volume and Issue: 22, P. 100111 - 100111

Published: Aug. 25, 2024

Probiotics are microbes associated with a wide range of health benefits and modulate gut flora by releasing effector molecules. The efficacy probiotics at various stages cancer treatment has been well demonstrated. can increase the potency cancer-based immunotherapy, which be administered before, during, or post-phase therapy. consumption among patients minimize detrimental effects chemotherapy act as potential tool for Genetically engineered express specific antigens that combat deadly pathogens. These essential features utilized in other applications. This review aims to provide updated information on mechanism action their applications Moreover, few significant like; antioxidative therapy, biotechnology-based improvement, developing potent probiotic strains effective also discussed.

Language: Английский

Citations

5
Impact of Lactocaseibacillus (Lactobacillus) paracasei sup. paracasei TISTR 2593 Probiotic Supplementation on the Gut Microbiome of Hypercholesterolemia Patients: A Randomized Controlled Trial DOI Open Access

Kamonsri Nuankham,

Jaruwan Sitdhipol, Pennapa Chonpathompikunlert

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 2916 - 2916

Published: Sept. 1, 2024

Probiotics have shown potential in managing hypercholesterolemia and related metabolic conditions. This study evaluated the effects of Lactocaseibacillus (Lactobacillus) paracasei sup. TISTR 2593 on gut microbiome health patients with hypercholesterolemia, was registered Thai Clinical Trial Registry (TCTR 20220917002). In a randomized, double-blind, placebo-controlled trial, 22 hypercholesterolemic participants received either probiotic or placebo daily for 90 days. Fecal samples collected before after intervention revealed significant changes, including decrease Subdoligranulum, linked to rheumatoid arthritis, an increase Flavonifractor, known its anti-inflammatory properties. Additionally, group exhibited reduction low-density lipoprotein cholesterol (LDL-C) levels. These findings suggest that L. can modulate improve health, warranting further investigation into mechanisms long-term benefits.

Language: Английский

Citations

4