Resveratrol’s bibliometric and visual analysis from 2014 to 2023 DOI Creative Commons

Haoyue Wei,

Guowei Fang,

Weina Song

et al.

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 8, 2024

Introduction Resveratrol (RSV) is a natural polyphenolic compound derived from variety of plants that possesses wide range biological activities, including antioxidant, anti-inflammatory, antitumor, antibacterial, antiviral, anti-aging, anti-radiation damage, anti-apoptosis, immune modulation, regulation glucolipid metabolism, inhibition lipid deposition, and anti-neuro. It therefore considered promising drug with the potential to treat diseases. Method In this study, using Web Science Core Collection (WoSCC) CiteSpace bibliometric tool, VOSviewer quantitatively visualized number countries, authors, institutions, publications, keywords, references 16,934 resveratrol-related papers 2014–2023 for quantitative qualitative analysis. Results The results showed an average 1693.4 were published per year, general upward trend. China had most publications 5877. Medical University was institution largest highest citations in field. research team mainly led by Prof. Richard Tristan, journal Molecular. Dietary polyphenols, oxidative stress, antioxidant anti-inflammatory effects are frequently cited articles. Oxidative apoptosis, expression, other keywords play important role connecting branches Discussion Our analysis indicates integration nanoparticles RSV poised become significant markedly inhibits harmful bacteria, fosters proliferation beneficial enhances diversity intestinal flora, thereby preventing flora dysbiosis. Additionally, exhibits both antibacterial antiviral properties. also promotes osteogenesis serves neuroprotective function models Alzheimer's disease. applications medicine healthcare vast. A future challenge lies modifying its structure develop derivatives superior activity bioavailability. coming years, innovative pharmaceutical formulations RSV, oral, injectable, topical preparations, may be developed enhance bioavailability therapeutic efficacy.

Language: Английский

Synaptic plasticity and neuroprotection: The molecular impact of flavonoids on neurodegenerative disease progression DOI

Spandana Rajendra Kopalli,

Tapan Behl,

Ashishkumar Kyada

et al.

Neuroscience, Journal Year: 2025, Volume and Issue: 569, P. 161 - 183

Published: Feb. 7, 2025

Language: Английский

Citations

1
Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats DOI Creative Commons
Judith R. A. van Rooij, Monica van den Berg, Tamara Vasilkovska

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 3, 2025

Introduction Dietary interventions such as caloric restriction (CR) exert positive effects on brain health. Unfortunately, poor compliance hinders the success of this approach. A proposed alternative is resveratrol (Rsv), a CR-mimetic known to promote Direct comparison between Rsv and CR health lacking, with limited knowledge their sex-specific effects. Therefore, we aimed compare unravel impact these dietary spontaneous activity. Methods Here, used resting-state fMRI investigate functional connectivity (FC) changes in five prominent networks (RSNs) healthy 4 month old male female F344 rats supplemented either 40% or daily supplementation (10 mg/kg, oral) for duration 1 month. Results Our results demonstrated decreased body weight (BW) rats, well an increase compared whereas difference sexes was not observed control groups. Furthermore, found that both induce female-specific decrease FC subcortical network hippocampal network, lateral cortical network. Moreover, lowered within default mode like sensory network—an effect rats. Discussion findings reveal similar RSNs associated memory emotion, all while dissimilar other within- between-RSN measures. Altogether, study provides insight into comparability short-term between-RSNs providing reference future research

Language: Английский

Citations

0
Natural products in neurodegenerative diseases: recent advances and future outlook DOI Creative Commons

Lutfun Nahar,

Rawiwan Charoensup,

Kulyash Kalieva

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: March 19, 2025

Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s are on the rise pose significant challenges due to lack of effective treatments. This review critically examines neuroprotective effects various natural products derived from plants, marine organisms, fungi. Natural have long been used in traditional medicine gaining attention modern drug discovery for their unique properties. The explains how these can protect neurons by influencing key biological pathways involved neurodegeneration. It discusses mechanisms including antioxidant effects, anti-inflammatory actions, modulation cellular signalling, support mitochondrial function. A systematic literature search was conducted minimize bias ensure rigorous study selection. Preclinical studies using animal models cell cultures show that secondary metabolites like polyphenols, alkaloids, terpenoids significantly reduce neuronal damage. Some clinical trials shown promising results. However, bioavailability, standardization, dosage must be addressed translate findings into practice. also evaluates potential synergy combining with conventional treatments, offering a complementary therapeutic approach. represent avenue developing innovative treatments neurodegenerative diseases. highlights research gaps proposes future directions. Future should focus overcoming existing refining improve efficacy safety settings. application knowledge has enhance quality life individuals affected

Language: Английский

Citations

0
Resveratrol’s bibliometric and visual analysis from 2014 to 2023 DOI Creative Commons

Haoyue Wei,

Guowei Fang,

Weina Song

et al.

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 8, 2024

Introduction Resveratrol (RSV) is a natural polyphenolic compound derived from variety of plants that possesses wide range biological activities, including antioxidant, anti-inflammatory, antitumor, antibacterial, antiviral, anti-aging, anti-radiation damage, anti-apoptosis, immune modulation, regulation glucolipid metabolism, inhibition lipid deposition, and anti-neuro. It therefore considered promising drug with the potential to treat diseases. Method In this study, using Web Science Core Collection (WoSCC) CiteSpace bibliometric tool, VOSviewer quantitatively visualized number countries, authors, institutions, publications, keywords, references 16,934 resveratrol-related papers 2014–2023 for quantitative qualitative analysis. Results The results showed an average 1693.4 were published per year, general upward trend. China had most publications 5877. Medical University was institution largest highest citations in field. research team mainly led by Prof. Richard Tristan, journal Molecular. Dietary polyphenols, oxidative stress, antioxidant anti-inflammatory effects are frequently cited articles. Oxidative apoptosis, expression, other keywords play important role connecting branches Discussion Our analysis indicates integration nanoparticles RSV poised become significant markedly inhibits harmful bacteria, fosters proliferation beneficial enhances diversity intestinal flora, thereby preventing flora dysbiosis. Additionally, exhibits both antibacterial antiviral properties. also promotes osteogenesis serves neuroprotective function models Alzheimer's disease. applications medicine healthcare vast. A future challenge lies modifying its structure develop derivatives superior activity bioavailability. coming years, innovative pharmaceutical formulations RSV, oral, injectable, topical preparations, may be developed enhance bioavailability therapeutic efficacy.

Language: Английский

Citations

1