Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(10), P. 2032 - 2032
Published: Oct. 8, 2024
Trichomonas
vaginalis
infection
is
one
of
the
most
prevalent
curable
STIs.
Although
treatments
are
available,
T.
infections
pose
a
significant
challenge,
especially
in
resource-limited
regions,
as
prevalence
this
STI
often
unknown.
We
aimed
to
determine
women
screened
for
cervical
cancer
precursor
lesions
Botucatu
São
Paulo,
Brazil.
conducted
descriptive
and
retrospective
study
that
included
23,735
who
attended
screening
program
at
health
units
2019
2022.
Clinical
sociodemographic
data
were
collected
from
information
system
(SISCAN)
test
requisition
forms.
Descriptive
analysis
was
conducted,
comparisons
performed
using
X2
Test
Student’s
t-test
(SigmaPlot
version
13.0).
The
0.84%
0.57%
mean
age
patients
with
trichomoniasis
42
(±11.2)
years;
75%
self-reported
white,
43%
married
or
stable
relationship,
40%
had
not
completed
primary
education.
Regarding
vaginal
microbiota,
only
15.3%
cytology
exams
by
showed
predominance
lactobacilli
species,
while
inflammation
present
82%
smears.
Cytological
revealed
0.05%
trichomoniasis,
including
ASC,
LSIL,
HSIL.
low
low-risk
BMC Infectious Diseases,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: March 28, 2025
Trichomonas
vaginalis
(T.
vaginalis)
is
one
of
the
most
prevalent
sexually
transmitted
infections
globally,
with
significant
regional
variations
in
its
prevalence.
This
study
aimed
to
examine
epidemiological
characteristics
T.
infection
Jingzhou,
Hubei
Province,
China.
To
obtain
prevalence
among
age
groups
and
different
years,
a
total
115,775
patients
from
2019
2023
were
included
this
study.
Two
detection
methods
including
immunochromatographic
assay
wet
mount
microscopy
used
detect
pathogens
vaginal
swabs
samples
other
pathogens,
such
as
Candida
albicans
(C.
albicans)
Gardnerella
Vaginalis
(G.
vaginalis).
The
overall
Jingzhou
was
3.41%,
demonstrating
decreasing
trend
2023,
particularly
decrease
during
COVID-19
pandemic
2020-2022
(P
<
0.001).
highest
positive
rate
observed
45-54
years
group
(4.87%),
while
lowest
25-34
(2.37%).
pregnant
women
(0.83%)
lower
than
that
non-pregnant
(1.87%),
statistically
difference
had
co-infection
(2.76%)
compared
single
(0.65%),
common
pattern
G.
(2.09%).
results
showed
there
relative
high
consistency
(Kappa:
0.841)
between
method
for
vaginalis.
Additionally,
elevated
leukocyte
levels
associated
higher
showing
2023.
group.
suggested
should
be
widely
implemented
screening
primary
healthcare
facilities.
ACS Infectious Diseases,
Journal Year:
2025,
Volume and Issue:
unknown
Published: June 5, 2025
The
globally
persistent
and
most
common
sexually
transmitted
agent
Trichomonas
vaginalis
continues
to
be
an
underestimated
public
health
threat.
Infection
with
T.
has
been
associated
reproductive
complications
increased
risk
of
HIV
acquisition.
With
the
available
diagnostic
tools
for
trichomoniasis,
there
is
still
unmet
demand
a
cost-effective,
facile,
rapid,
robust
tool.
We
report
on
design
utilization
tailed
primers
molecular
detection
vaginalis,
exploiting
isothermal
DNA
amplification
solid-phase
sandwich
colorimetric
assay.
use
primers,
in
combination
enzyme-linked
surface-tethered
complementary
probes,
straightforward
strategy
quantitatively
evaluate
maximize
target-specific
by
recombinase
polymerase
(RPA),
which
does
not
rely
typical
nuclease-probe
system.
quantitative
nature
microplate-based
oligonucleotide
assay
(ELONA)
that
relies
DNA-DNA
hybridization,
we
systematically
optimized
RPA
conditions
maximal
specific
target
fragment
genome.
developed
RPA-ELONA
limit
4.03
×
10-4
fg/μL
(3.99
aM)
synthetic
dsDNA
more
sensitive
than
PCR-based
using
same
primers.
analysis
biobanked
clinical
genomic
samples
showed
95%
accuracy
relative
qPCR
commercial
S-DiaMGTV
kit.
serves
as
guide
further
development
sandwich-based
POCT
vaginalis.
More
than
one
million
curable
sexually
transmitted
infections
occur
every
day.
Trichomonas
vaginalis
is
of
the
main
responsible
for
these
epidemiological
data,
however,
diagnosis
this
protozoan
still
mainly
based
on
microscopic
and
culture
identification.
The
commerciali-zation
immunological
tests
development
molecular
techniques
have
improved
sensitivity
classical
methods.
Nevertheless,
fact
that
trichomoniasis
a
neglected
parasitic
infection,
hinders
novel
their
implementation
in
routine
di-agnosis.
This
review
article
shows
different
methods
developed
to
identify
T.
population
difficulties
diagnose
male
asymptomatic
patients.
importance
including
parasite
gynecological
screening,
especially
pregnant
women,
considering
as
an
indicator
high-risk
sexual
behavior
also
discussed.
