Viruses and the Brain—A Relationship Prone to Trouble

Viruses, Journal Year: 2025, Volume and Issue: 17(2), P. 203 - 203

Published: Jan. 31, 2025

Neurological disorders, some of which are associated with viral infections, growing due to the aging and expanding population. Despite strong defenses central nervous system, viruses have evolved ways breach them, often result in dire consequences. In this review, we recount various by different can enter CNS, describe consequences such invasions. Consequences may manifest as acute disease, encephalitis, meningitis, or long-term effects, neuromuscular dysfunction, occurs poliomyelitis. We discuss evidence for involvement causation well-known chronic neurodegenerative diseases, Alzheimer's Parkinson's amyotrophic lateral sclerosis, multiple well vascular dementia elderly. also approaches currently available control a few neural infections. These include antivirals that effective against human immunodeficiency virus herpes simplex virus, vaccines valuable controlling rabies poliomyelitis flavivirus There is an urgent need better understand, at molecular level, how contribute and, especially, neurological diseases develop more precise therapies.

Language: Английский

De novo rescue of new henipaviruses under BSL-4 conditions – From sequence to pathogen

Advances in virus research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский