Exploring dermatological applications of Ammoides pusilla essential oil: evaluation of anti-aging, dermatoprotective and antimicrobial properties against dermatopathogenic microorganisms DOI Creative Commons
Mohamed Taibi, Amine Elbouzidi, Mounir Haddou

et al.

Discover Life, Journal Year: 2024, Volume and Issue: 54(1)

Published: Oct. 29, 2024

The aim of this study was the phytochemical characterization essential oil extracted from aerial parts (stems, leaves, and flowers) Ammoides pusilla (Brot.) Breistr (APEO) by use GC–MS. Importantly, GC–MS results revealed that APEO composed 10 terpene compounds, which carvacrol (52.84%), d-limonene (17.78%), β-Cymene (13.18%) γ-Terpinene (8.46%) predominate. These compounds are recognized for their important biological properties. demonstrated remarkable antimicrobial activity, outperforming positive controls in all cases. Inhibition diameters ranged 30.20 mm against Candida glabrata to 49.80 albicans, with minimum inhibitory concentrations (MICs) ranging 0.25% Staphylococcus aureus Micrococcus luteus 4.00% glabrata. This efficacy is attributed oil's rich bioactive molecules. also showed significant dose-dependent inhibition anti-tyrosinase IC50 29.59 ± 1.89 µg/mL monophenolase activity 17.56 0.76 diphenolase activity. At same time, elastase, an 20.90 3.16 µg/mL. sun protection factor (SPF) determined be 4.323. SPF value corresponds estimated 76.88% effectiveness blocking UVB radiation. suggest possesses promising dermatoprotective anti-aging In conclusion, exhibits notable antimicrobial, anti-elastase activities, paving way new natural therapeutic options skin problems, dermal applications.

Language: Английский

Exploring dermatological applications of Ammoides pusilla essential oil: evaluation of anti-aging, dermatoprotective and antimicrobial properties against dermatopathogenic microorganisms DOI Creative Commons
Mohamed Taibi, Amine Elbouzidi, Mounir Haddou

et al.

Discover Life, Journal Year: 2024, Volume and Issue: 54(1)

Published: Oct. 29, 2024

The aim of this study was the phytochemical characterization essential oil extracted from aerial parts (stems, leaves, and flowers) Ammoides pusilla (Brot.) Breistr (APEO) by use GC–MS. Importantly, GC–MS results revealed that APEO composed 10 terpene compounds, which carvacrol (52.84%), d-limonene (17.78%), β-Cymene (13.18%) γ-Terpinene (8.46%) predominate. These compounds are recognized for their important biological properties. demonstrated remarkable antimicrobial activity, outperforming positive controls in all cases. Inhibition diameters ranged 30.20 mm against Candida glabrata to 49.80 albicans, with minimum inhibitory concentrations (MICs) ranging 0.25% Staphylococcus aureus Micrococcus luteus 4.00% glabrata. This efficacy is attributed oil's rich bioactive molecules. also showed significant dose-dependent inhibition anti-tyrosinase IC50 29.59 ± 1.89 µg/mL monophenolase activity 17.56 0.76 diphenolase activity. At same time, elastase, an 20.90 3.16 µg/mL. sun protection factor (SPF) determined be 4.323. SPF value corresponds estimated 76.88% effectiveness blocking UVB radiation. suggest possesses promising dermatoprotective anti-aging In conclusion, exhibits notable antimicrobial, anti-elastase activities, paving way new natural therapeutic options skin problems, dermal applications.

Language: Английский

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