Applied Sciences,
Journal Year:
2021,
Volume and Issue:
11(21), P. 10156 - 10156
Published: Oct. 29, 2021
Deep
eutectic
solvents
are
liquid
mixtures
of
solid
components
at
room
temperature,
which
present
exceptional
properties:
high
solvent
capacity,
biodegradation,
low
volatile
organic
compound
character,
and
relatively
toxicity.
Furthermore,
there
an
important
number
DES
described,
formed
by
different
ratios,
thus,
the
studied
applications
also
numerous.
In
this
review,
we
focused
on
related
to
health.
One
most
promising
is
development
oral
formulations
poorly
soluble
active
pharmaceutical
ingredients,
although
it
currently
remains
early
stage.
We
have
analyzed
potential
limitations
with
regard.
been
used
as
synthesis
media.
work,
revised
use
obtain
bioactive
natural
products
via
or
extraction
process.
Finally,
usefulness
in
other
interesting
for
promoting
health
has
examined:
case
genomics
studies,
nano-carriers
encapsulation
anticancer
drugs
stabilization
samples
medical
purposes.
Polymers,
Journal Year:
2022,
Volume and Issue:
14(15), P. 3023 - 3023
Published: July 26, 2022
Nowadays,
there
are
still
numerous
challenges
for
well-known
biomedical
applications,
such
as
tissue
engineering
(TE),
wound
healing
and
controlled
drug
delivery,
which
must
be
faced
solved.
Hydrogels
have
been
proposed
excellent
candidates
these
they
promising
properties
the
mentioned
including
biocompatibility,
biodegradability,
great
absorption
capacity
tunable
mechanical
properties.
However,
depending
on
material
or
manufacturing
method,
resulting
hydrogel
may
not
up
to
specific
task
it
is
designed,
thus
different
approaches
enhance
performance
requirements
of
application
in
question.
The
main
purpose
this
review
article
was
summarize
most
recent
trends
technology,
going
through
used
polymeric
materials
popular
synthesis
methods
years,
strategies
enhancing
hydrogels'
properties,
cross-linking
manufacture
composite
hydrogels.
In
addition,
secondary
objective
briefly
discuss
other
novel
applications
hydrogels
that
past
few
years
drawn
a
lot
attention.
Journal of Agriculture and Food Research,
Journal Year:
2023,
Volume and Issue:
14, P. 100678 - 100678
Published: June 17, 2023
The
food
processing
sector
has
expanded
dramatically
over
the
past
ten
years,
particularly
with
regard
to
goods
that
are
high
in
biologically
active
compounds.
Thus,
efficacy
and
safety
of
extraction
techniques
have
also
received
attention.
There
is
currently
a
sharp
rise
research
articles
committed
creation
new
which
not
only
quick
affordable
but
more
effective
environmentally
friendly,
increasing
yields
extract
quality
without
use
potentially
dangerous
organic
solvents.
green
solvents
been
focus
study
meet
sustainable
development
goals.
Deep
eutectic
(DESs)
acknowledged
as
excellent
alternatives
due
their
simpler
manufacturing
procedure
100%
atom
economy,
cheap
cost,
probable
biodegradability,
negligible
toxicity.
DESs
become
popular
useful
liquid
proven
application
variety
chemical
reactions.
Wide
components
may
be
extracted
using
DES,
they
shown
for
applications
involving
food.
However,
possibility
industrial
scale-up
use,
however,
fully
examined.
Journal of Molecular Liquids,
Journal Year:
2024,
Volume and Issue:
398, P. 124250 - 124250
Published: Feb. 15, 2024
Deep
Eutectic
Solvents
(DES)
are
emerging
as
environmentally
friendly
and
effective
alternatives
in
membrane
technology,
offering
a
sustainable
edge
over
traditional
solvents.
This
review
compiles
the
latest
advancements
incorporation
of
DES
into
polymeric
systems
for
diverse
separation
processes,
including
ultrafiltration
(UF),
microfiltration
(MF),
nanofiltration
(NF),
reverse
osmosis
(RO),
forward
(FO),
pervaporation,
distillation
(MD).
Special
attention
is
devoted
to
preparation
methods
involving
Non-Solvent
Induced
Phase
Separation
(NIPS),
Interfacial
Polymerization
(IP),
electrospinning.
Notable
developments
include
integration
various
types,
such
Thin-Film
Composite
(TFC)
NF
FO,
Supported
Liquid
Membranes
(SLMs)
asymmetric
mixed
matrix
membranes
UF.
The
introduces
classification
either
hydrophilic
or
hydrophobic,
revealing
their
respective
roles
applications.
A
critical
examination
hydrogen
bond
donors
(HBD)
acceptors
(HBA)
offers
insights
mechanisms
behind
DES-based
membranes.
central
challenge
addressed
complex
behavior
leaching
within
membranes,
which
has
varying
implications
on
performance,
efficiency,
purity
filtration
processes.
While
some
studies
have
shed
light
stability
intentional
components
enhance
functionality,
research
notably
sparse
when
it
comes
specific
issue
water
highlights
an
existing
void
suggests
direction
future
studies.
comprehensive
serves
roadmap
further
development
wider
industrial
adoption
technologies
while
identifying
both
strengths
areas
improvement.
ChemistryOpen,
Journal Year:
2021,
Volume and Issue:
10(8), P. 815 - 829
Published: Aug. 1, 2021
Abstract
One
of
the
highlights
green
chemistry
is
development
techniques
and
procedures
with
low
environmental
impact.
In
last
years,
deep
eutectic
solvents
(DES)
have
become
an
important
alternative
to
conventional
organic
solvents.
For
a
period
ionic
liquids
provoked
remarkable
interest,
but
they
been
displaced
by
DES
because
show
easier
preparation
methods,
lower
prices,
many
them
are
biodegradable
compatible
biological
systems.
addition,
adjustable
physicochemical
properties,
high
thermal
stability,
volatility
water.
this
paper
reviewed
state
art
use
paying
special
attention
role
reaction
media
in
synthesis.
Separations,
Journal Year:
2021,
Volume and Issue:
8(10), P. 176 - 176
Published: Oct. 7, 2021
Deep
eutectic
solvents
(DES)
are
a
mixture
of
two
or
more
components
and
classified
as
ionic
with
special
properties
such
low
volatility,
high
solubility,
melting
points,
low-cost
materials
less
toxic
to
humans.
Using
DES
has
been
suggested
an
eco-friendly,
green
method
for
extraction
bioactive
compounds
from
medicinal
plants
safe
alternative
nutritional,
pharmaceutical
various
sector
applications.
Conventional
solvent
methods
present
drawbacks
long
period,
safety
issues,
harmful
the
environment,
costly
large
volume
required.
The
leads
higher
yield
better
bioactivity
results
compared
conventional
solvents.
This
review
provides
summary
research
progress
regarding
advantages
using
extract
phenolic
acid,
flavonoids,
isoflavones,
catechins,
polysaccharides,
curcuminoids,
proanthocyanidin,
phycocyanin,
gingerols,
ginsenosides,
anthocyanin,
xanthone,
volatile
monoterpenes,
tannins,
lignin,
pectin,
rutin,
tert-butyl
hydroquinone,
chlorogenic
acids,
resveratrol
others,
opposed
extracts
is
determined
antioxidant,
antibacterial
antitumor
activities.
Hence,
DESs
considered
potential
media
selective
efficient
extracting
ingredients
plants.
Materials,
Journal Year:
2021,
Volume and Issue:
14(10), P. 2494 - 2494
Published: May 12, 2021
Deep
Eutectic
Systems
(DESs)
are
obtained
by
combining
Hydrogen
Bond
Acceptors
(HBAs)
and
Donors
(HBDs)
in
specific
molar
ratios.
Since
their
first
appearance
the
literature
2003,
they
have
shown
a
wide
range
of
applications,
ranging
from
selective
extraction
biomass
or
metals
to
medicine,
as
well
pollution
control
systems
catalytic
active
solvents
co-solvents.
The
very
peculiar
physical
properties
DESs,
such
elevated
density
viscosity,
reduced
conductivity,
improved
solvent
ability
optical
behavior,
can
be
exploited
for
engineering
modular
which
cannot
with
other
non-eutectic
mixtures.
In
present
review,
selected
DESs
research
fields,
use
materials
synthesis,
volatile
organic
compounds,
ingredients
pharmaceutical
formulations
cosolvents
reported
discussed
terms
application
future
perspectives.
Abstract
Deep
eutectic
solvents
(DESs)
are
binary
or
ternary
mixtures
of
compounds
that
possess
significant
melting
point
depressions
relative
to
the
pure
isolated
components.
The
discovery
DESs
has
been
a
major
breakthrough
with
multiple
fields
benefitting
from
their
low
cost
and
tunable
physiochemical
properties.
However,
tailoring
for
specific
applications
through
practically
unlimited
synthetic
combinations
can
be
as
much
hindrance
benefit
given
expense
time‐required
perform
large‐scale
experimental
measurements.
This
emphasizes
need
fast
computational
tools
capable
making
accurate
predictions
DES
properties
exclusively
molecular
structure.
Yet,
these
systems
not
trivial
model
simulate
at
atomic
level
exceedingly
nonideal
behaviors,
asymmetry
components,
complexity
electrostatic
interactions.
Despite
challenge,
reports
featuring
quantum
mechanical
(QM)
methods
have
provided
understanding
into
relationship
between
depression
unique
complex
hydrogen
bond
network
present
in
DESs.
Classical
dynamics
(MD)
examined
bulk‐phase
solvent
organization
conjunction
thermodynamic
transport
Machine
learning
(ML)
algorithms
shown
great
potential
structure–property
prediction
tools.
Overall,
this
review
highlights
accomplishments
meaningfully
advanced
our
strives
give
reader
sense
overall
strengths
drawbacks
methodologies
employed
while
hinting
promises
advances
come.
article
is
categorized
under:
Software
>
Simulation
Methods
