Nanocomposite Nanofibers of Graphene—Fundamentals and Systematic Developments

Journal of Composites Science, Journal Year: 2023, Volume and Issue: 7(8), P. 323 - 323

Published: Aug. 7, 2023

Research on polymer nanocomposite nanofibers has seen remarkable growth over the past several years. One of main driving forces for this progress is increasing applicability technological applications. This review basically aims to present current state manufacturing polymer/graphene nanofiber nanocomposites, using appropriate techniques. Consequently, various conducting and thermoplastic polymers have been processed with graphene nano-reinforcement fabricate nanofibers. Moreover, numerous methods adopted fabrication nanocomposites including interfacial polymerization, phase separation, freeze drying, template synthesis, drawing techniques, etc. For formation nanofibers, electrospinning can be preferable due advantages such as need simple equipment, control morphology, superior properties obtained material. The techniques solution processing, melt spinning, spin coating also used manufacture Here, choice parameters affects final texture, properties. manufactured examined exceptional structural, microstructure, thermal, other physical rely content, dispersion, matrix–nanofiller interactions. potential investigated radiation shielding, supercapacitors, membranes, biomedical field. Hence, explains literature-driven significance incorporating in polymeric Conclusively, most studies focused technique design Future research field may lead advanced innovations technical applications To best our knowledge, reports are available topic; however, stated literature not a compiled updated form. Therefore, researchers encounter challenges achieving future advancements area graphene-based without first consulting recent literature, an assembled review, gain necessary insights, state-of-the-art explores manufacturing, properties,

Language: Английский

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Progress in the application of graphene and its derivatives to osteogenesis

Heliyon, Journal Year: 2023, Volume and Issue: 9(11), P. e21872 - e21872

Published: Nov. 1, 2023

As bone and joint injuries from various causes become increasingly prominent, how to effectively reconstruct repair defects presents a difficult problem for clinicians researchers. In recent years, graphene its derivatives have been the subject of growing body research found promote proliferation osteogenic differentiation stem cells. This provides new idea solving clinical defects. However, as numerous articles address aspects not fully systematized, there is an urgent need classify summarize them. this paper, first time, effects on cells in solution, 2D 3D structures vivo their possible mechanisms are reviewed, cytotoxic were summarized analyzed. The toxicity further reviewed. addition, we suggest future development directions tissue engineering applications provide reference application.

Language: Английский

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Preparation of graphene oxide–stabilized Pickering emulsion adjuvant for Pgp3 recombinant vaccine and enhanced immunoprotection against Chlamydia Trachomatis infection

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14

Published: April 18, 2023

Traditional emulsion adjuvants are limited in clinical application because of their surfactant dependence. Graphene oxide (GO) has unique amphiphilic properties and therefore potential to be used as a substitute stabilize Pickering emulsions.In this study, GO-stabilized (GPE) was prepared an adjuvant facilitate enhanced immune response the Chlamydia trachomatis (Ct) Pgp3 recombinant vaccine. Firstly, GPE by optimizing sonication conditions, pH, salinity, GO concentration, water/oil ratio. with small-size droplets characterized chosen candidate. Subsequently, controlled-release antigen delivery explored. Cellular uptake behaviors, M1 polarization, cytokine stimulation + considered terms production macrophages. Finally, GPE's effect evaluated vaccination BALB/c mouse models.GPE smallest droplet sizes under 163 W for 2 min at 1 mg/mL natural salinity pH when ratio 10:1 (w/w). The optimized average size 1.8 μm zeta -25.0 ± 1.3 mv. delivered antigens adsorption onto surface, demonstrating controlled release both vitro vivo. In addition, promoted uptake, which stimulated proinflammatory tumor necrosis factor alpha (TNF-α), enhancing polarization macrophages vitro. Macrophage recruitment also significantly injection site. treatment group, higher levels immunoglobin (IgG), G1 (IgG1), G2a (IgG2a) sera, A (IgA) were detected vaginal fluid, IFN-γ IL-2 secretion stimulated, than showing significant type T helper (Th1)-type cellular response. muridarum challenging showed that Pgp3's immunoprotection through its advanced clearance bacterial burden alleviation chronic pathological damage genital tract.This study enabled rational design GPE, shedding light on control release, macrophage recruitment, augmented humoral immunity ameliorated chlamydial-induced tissue tract.

Language: Английский

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Oriented Porous Polymer Scaffolds in Tissue Engineering: A Comprehensive Review of Preparation Strategies and Applications

Macromolecular Materials and Engineering, Journal Year: 2023, Volume and Issue: 309(1)

Published: Oct. 15, 2023

Abstract The pursuit of effective therapeutic strategies for tissue damage has prompted extensive scholarly investigations worldwide. Tissue engineering emerged as a prominent approach, particularly through the utilization artificial scaffolds that closely resemble natural extracellular matrix (ECM). These exhibit multi‐scale topological structures and surface physicochemical properties, which significantly influence cellular behavior, thereby attracting considerable attention from numerous researchers. This comprehensive review is concentrated on primary techniques employed in fabrication biodegradable polymer possessing oriented porous structures, most recent advancements research are presented. Significantly, profound scaffold characteristics underscored elucidating superiority pore over disordered ones mimicking distinctive attributes ECM. Enhanced cell adhesion, proliferation, differentiation represent notable advantages associated with scaffolds. Additionally, critical interplay between structure, performance, functionalization emphasized, highlighting imperative to optimize clinical application

Language: Английский

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Two‐Dimensional Nanomaterials‐Based Polymer Nanocomposites for Biomedical Applications

Published: May 20, 2024

Two-dimensional (2D) nanostructured materials have taken a special interest among researchers due to their layered structural feature with high aspect ratio showing versatile properties. nanomaterials like graphene, graphene oxide (GO), reduced (rGO), nanoclay, double hydroxide (LDH), metal organic framework (MOF), graphitic carbon nitride (g-C 3 N 4 ), hexagonal boron (h-BN), MXene, transition dichalcogenide (TMD), black phosphorus (BP), (TMO), and covalent (COF) are potential reinforcements in polymer nanocomposites (PNCs) by which different properties thermal properties, mechanical strength, gas barrier flame retarding nature, antibacterial behavior of PNCs enhanced, enabling application the biomedical field. When 2D reinforced polymers such as chitosan, poly(lactic acid) (PLA), poly(acrylic acid)(PAA), poly(vinyl alcohol) (PVA), poly(glycolic (PGA), poly(methyl methacrylate) (PMMA), albumin, then prepared become more useful for applications compared other reinforcing nanomaterials. The present chapter focuses on state-of-the-art nanomaterials-based drug delivery, tissue engineering, gene therapy, wound healing, biosensing. From critical analysis, it is found that sandwiched laminar structure unique factor change towards applications. Depending interfacial interaction surface polymer, graphene-based affinity Different analytically discussed inclusion schemes table better understanding readers.

Language: Английский

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