Journal of Nanomaterials,
Journal Year:
2023,
Volume and Issue:
2023, P. 1 - 15
Published: Sept. 19, 2023
The
remarkable
physicochemical
properties
of
nanomaterials
have
attracted
researchers
due
to
the
numerous
applications
in
field
chemistry,
biology,
and
physics.
Despite
various
applications,
superparamagnetic
iron
oxide
nanoparticles
(SPIONs)
are
harmful
living
organisms
environment
as
they
released
without
any
safety
testing.
In
this
study,
SPIONs
were
synthesized
further
characterized.
aim
study
was
examine
toxicity
against
animal
models:
Zebrafish—Danio
rerio,
Earthworm—Eudrilus
eugeniae,
Drosophila—Drosophila
melanogaster
through
histology
using
Hematoxylin–Eosin
Prussian
Blue
staining.
accumulation
quantified
by
Inductively
Coupled
Plasma
Mass
Spectrometry
(ICP-MS).
Through
images,
it
observed
that
had
caused
damages
a
lower
concentration
0.001–0.002
μg/ml
metal
detected
ICP-MS
analysis.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(7), P. 1829 - 1829
Published: June 26, 2023
Nanofiber
scaffolds
have
emerged
as
a
revolutionary
drug
delivery
platform
for
promoting
wound
healing,
due
to
their
unique
properties,
including
high
surface
area,
interconnected
porosity,
excellent
breathability,
and
moisture
absorption,
well
spatial
structure
which
mimics
the
extracellular
matrix.
However,
use
of
nanofibers
achieve
controlled
loading
release
still
presents
many
challenges,
with
ongoing
research
exploring
how
load
drugs
onto
nanofiber
without
loss
activity
control
in
specific
spatiotemporal
manner.
This
comprehensive
study
systematically
reviews
applications
recent
advances
related
drug-laden
skin-wound
management.
First,
we
introduce
commonly
used
methods
preparation,
electrostatic
spinning,
sol-gel,
molecular
self-assembly,
thermally
induced
phase
separation,
3D-printing
techniques.
Next,
summarize
polymers
preparation
utilizing
scaffolds.
We
then
review
application
drug-loaded
considering
different
stages
healing
acts.
Finally,
briefly
describe
stimulus-responsive
schemes
scaffolds,
other
exciting
systems.
Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(9), P. 241 - 241
Published: Aug. 23, 2024
The
rising
demand
for
effective
bone
regeneration
has
underscored
the
limitations
of
traditional
methods
like
autografts
and
allografts,
including
donor
site
morbidity
insufficient
biological
signaling.
This
review
examines
nanoparticles
(NPs)
in
tissue
engineering
(TE)
to
address
these
challenges,
evaluating
polymers,
metals,
ceramics,
composites
their
potential
enhance
osteogenesis
angiogenesis
by
mimicking
extracellular
matrix
(ECM)
nanostructure.
involved
synthesizing
characterizing
nanoparticle-based
scaffoldsand
integrating
hydroxyapatite
(HAp)
with
polymers
mechanical
properties
osteogenic
potential.
results
showed
that
NPs
significantly
promote
cell
growth,
differentiation,
formation,
carbon-based
graphene
carbon
nanotubes
showing
promise.
offer
versatile,
biocompatible,
customizable
scaffolds
drug
delivery
support
repair.
Despite
promising
results,
challenges
cytotoxicity,
biodistribution,
immune
responses
remain.
Addressing
issues
through
surface
modifications
biocompatible
molecules
can
improve
biocompatibility
efficacy
nanomaterials.
Future
research
should
focus
on
long-term
vivo
studies
assess
safety
NP-based
explore
synergistic
effects
other
bioactive
or
growth
factors.
underscores
transformative
advancing
BTE
calls
further
optimize
technologies
clinical
applications.
Journal of Agriculture and Food Research,
Journal Year:
2024,
Volume and Issue:
18, P. 101307 - 101307
Published: July 22, 2024
Meat
is
the
main
and
important
source
of
protein,
minerals,
vitamins
plays
a
crucial
role
in
human
nutrition.
Based
on
projections,
consumption
it
expected
to
increase
twofold
by
2050
as
result
population
growth.
Conversely,
this
surge
meat
production
gives
rise
issues
such
indiscriminate
slaughter
animals,
escalation
methane
gas
subsequent
exacerbation
global
warming
phenomenon,
heightened
risk
shared
diseases
between
humans
emergence
antibiotic-resistant
strains
pathogens,
well
excessive
water
usage.
There
will
be
significant
amount,
therefore,
imperative
explore
novel
approaches,
employing
lab-grown
meat.
Current
research
field
primarily
centered
around
cultured
These
meats
offer
numerous
benefits,
their
eco-friendliness
ability
mitigate
animal-borne
illnesses.
In
process
cultivating
meat,
stem
or
satellite
cells
are
extracted
from
animal's
muscle
tissue
without
causing
harm
animal.
then
placed
culture
medium
containing
fetal
bovine
serum.
Subsequently,
they
employ
either
edible
non-edible
scaffolds
means
facilitating
cell
proliferation,
which
introduced
into
bioreactor
induce
growth
tissue.
Under
optimal
conditions,
including
appropriate
temperature,
oxygen
levels,
nutrient
availability,
factors,
typically
takes
approximately
3–5
weeks
for
thin
piece
develop.
Presently,
feasibility
adopting
severely
limited
its
exorbitant
cost,
substandard
colour
taste,
lack
acceptance
various
religious
groups.
Enhancing
can
achieved
incorporating
compounds
like
red
beetroot
saffron,
while
taste
enhanced
fatty
acids,
fats,
protein.
It
acknowledge
that
technology
still
initial
phases
order
achieve
widespread
production,
attain
satisfactory
level
consumer
approval.
Furthermore,
adoption
may
potentially
lead
decrease
income
livestock
breeders.
However,
given
inherent
risks
associated
with
industry,
proceed
direction.
Also,
3D
printing
an
advancing
digital
has
vast
market
potential
food
nutrition
technology.
offers
platform
creating
distinctive
products
have
improved
sensory
nutritional
qualities,
specifically
tailored
particular
consumer.
provide
distinct
solutions
challenges
controlling
fat,
other
composition,
lifelike
texture.
The
man-made
materials
used
engineering
polystyrene,
polylactic
acid
(PLA),
polyglycolic
(PGA),
mixture
acids
called
PLGA.
Journal of Tissue Engineering,
Journal Year:
2024,
Volume and Issue:
15
Published: Jan. 1, 2024
The
liver
coordinates
over
500
biochemical
processes
crucial
for
maintaining
homeostasis,
detoxification,
and
metabolism.
Its
specialized
cells,
arranged
in
hexagonal
lobules,
enable
it
to
function
as
a
highly
efficient
metabolic
engine.
However,
diseases
such
cirrhosis,
fatty
disease,
hepatitis
present
significant
global
health
challenges.
Traditional
drug
development
is
expensive
often
ineffective
at
predicting
human
responses,
driving
interest
advanced
vitro
models
utilizing
3D
bioprinting
microfluidics.
These
strive
mimic
the
liver’s
complex
microenvironment,
improving
screening
disease
research.
Despite
its
resilience,
vulnerable
chronic
illnesses,
injuries,
cancers,
leading
millions
of
deaths
annually.
Organ
shortages
hinder
transplantation,
highlighting
need
alternative
treatments.
Tissue
engineering,
employing
polymer-based
scaffolds
bioprinting,
shows
promise.
This
review
examines
these
innovative
strategies,
including
organoids
tissue-on-chip
technologies,
address
challenges
diseases.
